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Volumn 156, Issue 1, 1996, Pages 395-404

Cytokine and alloantibody networks in long term cardiac allografts in rat recipients treated with rapamycin

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIBODY; CYTOKINE; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; RAPAMYCIN;

EID: 0030027421     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (50)

References (57)
  • 1
    • 85025352713 scopus 로고
    • Rapamycins: Antifungal, antitumor, antiproliferative, and immunosuppressive macrolides
    • Morris, R. E 1992 Rapamycins: antifungal, antitumor, antiproliferative, and immunosuppressive macrolides. Transplant. Rev. 6:39.
    • (1992) Transplant. Rev. , vol.6 , pp. 39
    • Morris, R.E.1
  • 2
    • 0026748870 scopus 로고
    • Cyclosporin A, FK-506, and rapamycin: Pharmacologic probes of lymphocyte signal transduction
    • Sigal, N. H., and F J Dumont 1992 Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction. Annu. Rev. Immunol. 10:519
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 519
    • Sigal, N.H.1    Dumont, F.J.2
  • 3
    • 0024345850 scopus 로고
    • Identification of a new pharmacologic action for an old compound
    • Morris, R. E., and B M. Meiser 1989 Identification of a new pharmacologic action for an old compound. Med Sci. Res 17:877.
    • (1989) Med Sci. Res , vol.17 , pp. 877
    • Morris, R.E.1    Meiser, B.M.2
  • 5
    • 0026024078 scopus 로고
    • Rapamycin, a potent immunosuppressive drug for vascularized heart, kidney and small bowel transplantation in the rat
    • Stepkowski, S M., H. Chen, P. Daloze, and B. D. Kahan. 1991 Rapamycin, a potent immunosuppressive drug for vascularized heart, kidney and small bowel transplantation in the rat. Transplantation 51:22.
    • (1991) Transplantation , vol.51 , pp. 22
    • Stepkowski, S.M.1    Chen, H.2    Daloze, P.3    Kahan, B.D.4
  • 6
    • 0344632370 scopus 로고
    • Initial studies of the efficacy and safety of rapamycin (RPM) administered to cynomolgus monkey recipients of heart allografts
    • Morris, R., J. Wang, and C. Gregory. 1991. Initial studies of the efficacy and safety of rapamycin (RPM) administered to cynomolgus monkey recipients of heart allografts. J. Heart Lung Transplant 10:182.
    • (1991) J. Heart Lung Transplant , vol.10 , pp. 182
    • Morris, R.1    Wang, J.2    Gregory, C.3
  • 7
    • 0026063950 scopus 로고
    • Use of rapamycin for the suppression of alloimmune reactions m vivo: Schedule dependence, tolerance induction, synergy with cyclosporine and FK 506, and effect on host-versus-graft and graft-versus-host reactions
    • Morris, R. E , B. M. Meiser, J Wu, R. Shorthouse, and J. Wang. 1991. Use of rapamycin for the suppression of alloimmune reactions m vivo: schedule dependence, tolerance induction, synergy with cyclosporine and FK 506, and effect on host-versus-graft and graft-versus-host reactions. Transplant. Proc 23:521
    • (1991) Transplant. Proc , vol.23 , pp. 521
    • Morris, R.E.1    Meiser, B.M.2    Wu, J.3    Shorthouse, R.4    Wang, J.5
  • 8
    • 0025950431 scopus 로고
    • Reversal of ongoing rejection of allografts by rapamycin
    • Chen, H. J., J. P. Wu, H. Y. Luo, and P. M Daloze. 1991. Reversal of ongoing rejection of allografts by rapamycin. Transplant. Proc. 23:2241.
    • (1991) Transplant. Proc. , vol.23 , pp. 2241
    • Chen, H.J.1    Wu, J.P.2    Luo, H.Y.3    Daloze, P.M.4
  • 9
    • 0027301130 scopus 로고
    • Rapamycin inhibits arterial intimai thickening caused by both alloimmune and mechanical injury
    • Gregory, C R , P. Huie, M. E Billingham, and R. E. Morris. 1993. Rapamycin inhibits arterial intimai thickening caused by both alloimmune and mechanical injury. Transplantation 55:1409.
    • (1993) Transplantation , vol.55 , pp. 1409
    • Gregory, C.R.1    Huie, P.2    Billingham, M.E.3    Morris, R.E.4
  • 11
    • 0025259841 scopus 로고
    • CsA and anti-interleukin 2-receptor monoclonal antibody therapy in rats suppress accelerated rejection of cardiac allografts through different effector mechanisms
    • Hancock, W. W., R Di Stefano, P Braun, R Schweizer, N. L Tilney, and J. W. Kupiec-Weglinski 1990. CsA and anti-interleukin 2-receptor monoclonal antibody therapy in rats suppress accelerated rejection of cardiac allografts through different effector mechanisms. Transplantation 48:416
    • (1990) Transplantation , vol.48 , pp. 416
    • Hancock, W.W.1    Di Stefano, R.2    Braun, P.3    Schweizer, R.4    Tilney, N.L.5    Kupiec-Weglinski, J.W.6
  • 12
    • 0027332312 scopus 로고
    • CD4 mAb therapy modulates alloantibody production and intracardiac graft deposition in association with selective inhibition of Th1 lymphokines
    • Kupiec-Weglinski, J. W., B. Wasowska, I. Papp, G Schmidbauer, M. H. Sayegh, W M. Baldwin III, K. J. Wieder, and W W Hancock. 1993 CD4 mAb therapy modulates alloantibody production and intracardiac graft deposition in association with selective inhibition of Th1 lymphokines. J. Immunol. 151:5053.
    • (1993) J. Immunol. , vol.151 , pp. 5053
    • Kupiec-Weglinski, J.W.1    Wasowska, B.2    Papp, I.3    Schmidbauer, G.4    Sayegh, M.H.5    Baldwin III, W.M.6    Wieder, K.J.7    Hancock, W.W.8
  • 15
    • 0028209321 scopus 로고
    • Rapamycin abrogates accelerated rejection in sensitized rats by inhibiting alloantibody responses and selectively suppressing intragraft mononuclear and endothelial cell activation, cytokine production and cell adhesion
    • Schmidbauer, G., W. W Hancock, B. Wasowska, A. M. Badger, and J. W. Kupiec-Weglinski. 1994. Rapamycin abrogates accelerated rejection in sensitized rats by inhibiting alloantibody responses and selectively suppressing intragraft mononuclear and endothelial cell activation, cytokine production and cell adhesion. Transplantation 57:933.
    • (1994) Transplantation , vol.57 , pp. 933
    • Schmidbauer, G.1    Hancock, W.W.2    Wasowska, B.3    Badger, A.M.4    Kupiec-Weglinski, J.W.5
  • 16
    • 0013589776 scopus 로고
    • Interferon-γ and its receptor
    • Halloran, P., and N Goes. 1993 Interferon-γ and its receptor Transplant. Sci. 3:92
    • (1993) Transplant. Sci. , vol.3 , pp. 92
    • Halloran, P.1    Goes, N.2
  • 17
    • 0027530129 scopus 로고
    • Interleukin 12 and tumor necrosis factor are costimulators of interferon-γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist
    • Tripp, C. S., S. F. Wolf, and E. R. Unanue. 1993. Interleukin 12 and tumor necrosis factor are costimulators of interferon-γ production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist Proc. Natl. Acad Sci. USA 90:3725.
    • (1993) Proc. Natl. Acad Sci. USA , vol.90 , pp. 3725
    • Tripp, C.S.1    Wolf, S.F.2    Unanue, E.R.3
  • 18
    • 43949163341 scopus 로고
    • Interleukin-12 and its role in the generation of Th1 cells
    • Trinchieri, G. 1993 Interleukin-12 and its role in the generation of Th1 cells. Immunol Today 14:335
    • (1993) Immunol Today , vol.14 , pp. 335
    • Trinchieri, G.1
  • 19
    • 0025819340 scopus 로고
    • Induction of interferon-γ production by natural killer cells stimulatory factor: Characterization of responder cells and synergy with other inducers
    • Chan, S. H , B Perussia, J W Gupta, M. Kobayashi, M Pospisil, H. A. Young, S F. Wolf, D Young, S. C. Clark, and G. Trinchieri. 1991. Induction of interferon-γ production by natural killer cells stimulatory factor: characterization of responder cells and synergy with other inducers J Exp. Med 173:869.
    • (1991) J Exp. Med , vol.173 , pp. 869
    • Chan, S.H.1    Perussia, B.2    Gupta, J.W.3    Kobayashi, M.4    Pospisil, M.5    Young, H.A.6    Wolf, S.F.7    Young, D.8    Clark, S.C.9    Trinchieri, G.10
  • 20
    • 0026592604 scopus 로고
    • Mechanisms of IFN-γ induction by natural killer cell stimulatory factor (NKSF/IL-12)
    • Chan, S , M. Kobayashi, D. Santoli, B. Perussia, and G Trinchieri. 1992 Mechanisms of IFN-γ induction by natural killer cell stimulatory factor (NKSF/IL-12). J Immunol 148:92.
    • (1992) J Immunol , vol.148 , pp. 92
    • Chan, S.1    Kobayashi, M.2    Santoli, D.3    Perussia, B.4    Trinchieri, G.5
  • 21
    • 0027240219 scopus 로고
    • Interleukin 10 (IL-10) inhibits human lymphocyte interferon-γ production by suppressing natural killer stimulatory factor/IL-12 synthesis in accessory cells
    • D'Andrea, A., M. Aste-Amezaga, N. M. Valiante, X. Ma, M. Kubin, and G. Trinchieri 1993. Interleukin 10 (IL-10) inhibits human lymphocyte interferon-γ production by suppressing natural killer stimulatory factor/IL-12 synthesis in accessory cells J. Exp. Med 178:1041.
    • (1993) J. Exp. Med , vol.178 , pp. 1041
    • D'Andrea, A.1    Aste-Amezaga, M.2    Valiante, N.M.3    Ma, X.4    Kubin, M.5    Trinchieri, G.6
  • 26
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin, J M , A E. Przybyla, R I. MacDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294.
    • (1979) Biochemistry , vol.18 , pp. 5294
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.I.3    Rutter, W.J.4
  • 27
    • 0026027479 scopus 로고
    • Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway
    • Dallman, M. J., O. Shiho, T. H Page, K. J. Wood, and P J. Morris. 1991. Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway. J Exp Med. 173:79.
    • (1991) J Exp Med. , vol.173 , pp. 79
    • Dallman, M.J.1    Shiho, O.2    Page, T.H.3    Wood, K.J.4    Morris, P.J.5
  • 28
    • 0024384587 scopus 로고
    • Sequence of rat interleukin 2 and analogous binding of a mouse cDNA probe to rat MHC class II associated invariant chain mRNA
    • McKnight, A. J., D. W Mason, and A. N. Barclay. 1989. Sequence of rat interleukin 2 and analogous binding of a mouse cDNA probe to rat MHC class II associated invariant chain mRNA. Immunogenetics 30:145.
    • (1989) Immunogenetics , vol.30 , pp. 145
    • McKnight, A.J.1    Mason, D.W.2    Barclay, A.N.3
  • 29
    • 0025890963 scopus 로고
    • Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4+ T cells
    • McKnight, A J., A. N. Barclay, and D W. Mason 1991 Molecular cloning of rat interleukin 4 cDNA and analysis of the cytokine repertoire of subsets of CD4+ T cells J. Immunol 21:1187.
    • (1991) J. Immunol , vol.21 , pp. 1187
    • McKnight, A.J.1    Barclay, A.N.2    Mason, D.W.3
  • 30
    • 0027074148 scopus 로고
    • Synthesis and characterization of rat interleukin-10 (IL-10) c DNA clones from the RNA of cultured OX8-OX22-thoracic duct T cells
    • Goodmann, R E , J. Oblak, and R. G. Bell. 1992. Synthesis and characterization of rat interleukin-10 (IL-10) c DNA clones from the RNA of cultured OX8-OX22-thoracic duct T cells. Biochem. Biophys. Res. Commun 189:1
    • (1992) Biochem. Biophys. Res. Commun , vol.189 , pp. 1
    • Goodmann, R.E.1    Oblak, J.2    Bell, R.G.3
  • 32
    • 0028358905 scopus 로고
    • Quantitative comparison of rapamycin and cyclosporine effects on cytokine gene expression studied by reverse transcriptase-competitive polymerase chain reaction
    • Zheng, X. X., T. B. Strom, and A W. Steele. 1994. Quantitative comparison of rapamycin and cyclosporine effects on cytokine gene expression studied by reverse transcriptase-competitive polymerase chain reaction Transplantation 58:87.
    • (1994) Transplantation , vol.58 , pp. 87
    • Zheng, X.X.1    Strom, T.B.2    Steele, A.W.3
  • 33
    • 0027452517 scopus 로고
    • The association of enhancement of renal allograft survival by donor-specific blood transfusion with host MHC-linked inhibition of IgG anti-donor class I alloantibody responses
    • Wasowska, B , W M. Baldwin, D N. Howell, and R Sanfilippo. 1993. The association of enhancement of renal allograft survival by donor-specific blood transfusion with host MHC-linked inhibition of IgG anti-donor class I alloantibody responses. Transplantation 56:672.
    • (1993) Transplantation , vol.56 , pp. 672
    • Wasowska, B.1    Baldwin, W.M.2    Howell, D.N.3    Sanfilippo, R.4
  • 34
    • 0023588183 scopus 로고
    • A molecular titration assay to measure transcript prevalence levels
    • Lee, J J , and N. A Costlow 1987. A molecular titration assay to measure transcript prevalence levels Methods Enzymol. 152:633.
    • (1987) Methods Enzymol. , vol.152 , pp. 633
    • Lee, J.J.1    Costlow, N.A.2
  • 35
    • 0026666050 scopus 로고
    • Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin
    • Calvo, V , C M Crews, T A. Vik, and B E. Bierer 1992 Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. Proc. Natl. Acad Sci. USA 89:7571.
    • (1992) Proc. Natl. Acad Sci. USA , vol.89 , pp. 7571
    • Calvo, V.1    Crews, C.M.2    Vik, T.A.3    Bierer, B.E.4
  • 36
    • 0025099697 scopus 로고
    • Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin
    • Dumont, F J., M. J. Staruch, S. L Koprak, M. R Melino, and N. H. Sigal 1990. Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin, J. Immunol. 144:251.
    • (1990) J. Immunol. , vol.144 , pp. 251
    • Dumont, F.J.1    Staruch, M.J.2    Koprak, S.L.3    Melino, M.R.4    Sigal, N.H.5
  • 38
    • 0028964465 scopus 로고
    • Cytokine signalling through nonreceptor protein tyrosine kinases
    • Taniguchi, T. 1995 Cytokine signalling through nonreceptor protein tyrosine kinases Science 268 251.
    • (1995) Science , vol.268 , pp. 251
    • Taniguchi, T.1
  • 39
    • 0027409793 scopus 로고
    • Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells
    • Manetti, R., P Parronchi, M G. Giudizi, M P Piccinni, E Maggi, G. Trinchieri, and S. Romagnani. 1993 Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells. J. Exp Med. 177:1199.
    • (1993) J. Exp Med. , vol.177 , pp. 1199
    • Manetti, R.1    Parronchi, P.2    Giudizi, M.G.3    Piccinni, M.P.4    Maggi, E.5    Trinchieri, G.6    Romagnani, S.7
  • 40
    • 0028329177 scopus 로고
    • Effects of IL-12 on helper T cell dependent immune responses in vivo
    • McKnight, A. J , G. J. Zimmer, I. Fogelman, S. F. Wolf, and A. K Abbas. 1994. Effects of IL-12 on helper T cell dependent immune responses in vivo. J. Immunol 152:2172
    • (1994) J. Immunol , vol.152 , pp. 2172
    • McKnight, A.J.1    Zimmer, G.J.2    Fogelman, I.3    Wolf, S.F.4    Abbas, A.K.5
  • 43
    • 0029086366 scopus 로고
    • Sequential cytokine dynamics in chronic rejection of rat renal allografts roles for cytokines RANTES and MCP-1
    • Nadeau, K. C., H. Azuma, and N L. Tilney. 1995. Sequential cytokine dynamics in chronic rejection of rat renal allografts roles for cytokines RANTES and MCP-1 Proc. Natl Acad Sci. USA 92:8729.
    • (1995) Proc. Natl Acad Sci. USA , vol.92 , pp. 8729
    • Nadeau, K.C.1    Azuma, H.2    Tilney, N.L.3
  • 45
    • 0027264849 scopus 로고
    • Interleukin 12 is required for the T-lymphocyte-dependent induction of interferon-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts
    • Gazzinelli, R T , S Hieny, T. A Wynn, S Wolf, and A Sher. 1993. Interleukin 12 is required for the T-lymphocyte-dependent induction of interferon-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts Proc Natl. Acad. Sci. USA 90:6115.
    • (1993) Proc Natl. Acad. Sci. USA , vol.90 , pp. 6115
    • Gazzinelli, R.T.1    Hieny, S.2    Wynn, T.A.3    Wolf, S.4    Sher, A.5
  • 46
    • 0028265155 scopus 로고
    • Interleukin 12 induces stable priming for interferon γ (IFN-γ) production during differentiation of human T helper (Th) cells and transient IFN-γ production in established Th2 clones
    • Manetti, R., F. Gerosa, M. G Giudizi, R Biagotti, P. Parronchi, M P. Piccini, S Sampognaro, E. Maggi, S. Romagnani, and G. Trinchieri 1994. Interleukin 12 induces stable priming for interferon γ (IFN-γ) production during differentiation of human T helper (Th) cells and transient IFN-γ production in established Th2 clones. J. Exp Med 179:1273
    • (1994) J. Exp Med , vol.179 , pp. 1273
    • Manetti, R.1    Gerosa, F.2    Giudizi, M.G.3    Biagotti, R.4    Parronchi, P.5    Piccini, M.P.6    Sampognaro, S.7    Maggi, E.8    Romagnani, S.9    Trinchieri, G.10
  • 48
    • 0000930499 scopus 로고
    • The relationship of IL-4, IL-10 and other cytokines to transplantation tolerance
    • Lowry, R P. 1993. The relationship of IL-4, IL-10 and other cytokines to transplantation tolerance. Transplant. Sci. 3:104.
    • (1993) Transplant. Sci. , vol.3 , pp. 104
    • Lowry, R.P.1
  • 50
    • 0028026941 scopus 로고
    • Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats
    • Ferraresso, M , L. Tian, R. Ghobrial, S. M. Stepkowski, and B. D. Kahan. 1994. Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats. J. Immunol 153:3307.
    • (1994) J. Immunol , vol.153 , pp. 3307
    • Ferraresso, M.1    Tian, L.2    Ghobrial, R.3    Stepkowski, S.M.4    Kahan, B.D.5
  • 52
    • 0028280636 scopus 로고
    • Pancreatic islet production of murine interleukin-10 does not inhibit immune-mediated tissue destruction
    • Lee, M. L , L Wogensen, J. Shizuru, M. B. A. Oldstone, and N Sarvetnick. 1994. Pancreatic islet production of murine interleukin-10 does not inhibit immune-mediated tissue destruction. J. Clin. Invest. 93:1332.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1332
    • Lee, M.L.1    Wogensen, L.2    Shizuru, J.3    Oldstone, M.B.A.4    Sarvetnick, N.5
  • 53
    • 0029020011 scopus 로고
    • Administration of non-cytolytic IL-10/Fc in murine models of lipopolysaccharide-induced septic shock and allogeneic islet transplantation
    • Zheng, X., A. W. Steele, P. W. Nickerson, W. Steurer, J. Steiger, and T. B Strom. 1995 Administration of non-cytolytic IL-10/Fc in murine models of lipopolysaccharide-induced septic shock and allogeneic islet transplantation J. Immunol 154:5590.
    • (1995) J. Immunol , vol.154 , pp. 5590
    • Zheng, X.1    Steele, A.W.2    Nickerson, P.W.3    Steurer, W.4    Steiger, J.5    Strom, T.B.6
  • 54
    • 0020636586 scopus 로고
    • The mechanism of synergistic complement-mediated lysis of rat red cells by monoclonal IgG antibodies
    • Hughes-Jones, N. C., B. D. Gorick, and J. C. Howard. 1983. The mechanism of synergistic complement-mediated lysis of rat red cells by monoclonal IgG antibodies. Eur. J. Immunol. 13:635.
    • (1983) Eur. J. Immunol. , vol.13 , pp. 635
    • Hughes-Jones, N.C.1    Gorick, B.D.2    Howard, J.C.3
  • 55
    • 0019154418 scopus 로고
    • Differences in the ability of rat IgG subclasses to consume complement in homologous and heterologous serum
    • Fust, G., G. A. Medgyesi, H. Bazin, and J. Gergely. 1980. Differences in the ability of rat IgG subclasses to consume complement in homologous and heterologous serum. Immunol. Lett. 1:249.
    • (1980) Immunol. Lett. , vol.1 , pp. 249
    • Fust, G.1    Medgyesi, G.A.2    Bazin, H.3    Gergely, J.4
  • 57
    • 0024268801 scopus 로고
    • K-cell mediated cytotoxicity induced with rat monoclonal antibodies. I Antibodies of various isotypes differ in their ability to induce cytotoxicity mediated by rat and human effectors
    • Chassoux, D. M., L. G. Linares-Cruiz, H Bazin, and M. Stanislawski. 1988. K-cell mediated cytotoxicity induced with rat monoclonal antibodies. I Antibodies of various isotypes differ in their ability to induce cytotoxicity mediated by rat and human effectors. Immunology 65:623.
    • (1988) Immunology , vol.65 , pp. 623
    • Chassoux, D.M.1    Linares-Cruiz, L.G.2    Bazin, H.3    Stanislawski, M.4


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