Induction of IgE antibodies with predefined specificity in rhesus monkeys with recombinant birch pollen allergens, Bet v 1 and Bet v 2

Journal of Allergy and Clinical Immunology

Volumn 97, Issue 1 I, 1996, Pages 95-103

  Ferreira, Fatima D ^a   Mayer, Peter ^b   Sperr, Wolfgang R ^c   Valent, Peter ^c   Seiberler, Susanne ^c   Ebner, Christof ^c   Liehl, Ekke ^b   Scheiner, Otto ^c   Kraft, Dietrich ^c   Valenta, Rudolf ^c  

^a UNIVERSITY OF SALZBURG   (Austria)

^b NOVARTIS PHARMA AG   (Switzerland)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

Bet v 1; IgE; profilin Bet v 2; recombinant tree pollen allergens; rhesus monkeys; Type I allergy

Indexed keywords

DODECYL SULFATE SODIUM; IMMUNOGLOBULIN E; POLLEN ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CROSS REACTION; ESCHERICHIA COLI; GENE EXPRESSION; HISTAMINE RELEASE; IMMUNIZATION; NONHUMAN; POLLEN ALLERGY; PRIORITY JOURNAL; PROVOCATION TEST; RHESUS MONKEY; SKIN TEST;

EID: 0030027307     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(96)70287-7     Document Type: Article

References (38)

1. Ishizaki T, Koizumi K, Ikemori R, Ishiyama Y, Kushibiki E. Studies of prevalence of Japanese cedar pollinosis among the residents in a densely cultivated area. Ann Allergy 1987;58:265-70.
2. Wüthrich B. In Switzerland, pollinosis has really increased in the last decade. Allergy Clin Immunol News 1991;3:41-5.
3. Breitenbach M, Valenta R, Breiteneder H, Pettenburger K, Scheiner O, Rumpold H, Kraft D. Introduction to cDNA-cloning of plant allergens. In Epitopes of atopic allergens, A.H. Sehon and D. Kraft, eds. Brussels: UCB Institute of Allergy, 1990;57-60.
4. Fang KYS, Vitale M, Fehlner P, King TP. cDNA cloning and primary structure of a white faced hornet venom allergen V. Proc Natl Acad Sci USA 1989;85:895-9.
5. Chua KY, Stewart GA, Thomas WR, Simpson RJ, Dilworth RJ, Plozza TM, Turner KJ. Sequence analysis of cDNA coding for a major house dust mite allergen Der p 1: homology with cysteine proteases. J Exp Med 1988;167:175-82.
6. Breiteneder H, Pettenburger K, Bito A, Valenta R, Kraft D, Rumpold H, Scheiner O, Breitenbach M. The gene coding for the major birch pollen allergen Bet v 1, is highly homologous to a pea disease resistance response gene. EMBO J 1989;8:1935-8.
7. Valenta R, Duchêne M, Vrtala S, Birkner T, Ebner C, Hirschwehr R, Breitenbach M, Rumpold H, Scheiner O, Kraft D. Recombinant allergens for immunoblot diagnosis of tree-pollen allergy. J ALLERGY CLIN IMMUNOL 1991;88:889-94.
8. Valenta R, Duchêne M, Ebner C, Valent P, Sillaber C, Deviller P, Ferreira F, Tejkl M, Edelmann H, Kraft D, Scheiner O. Profilins constitute a novel family of functional plant pan-allergens. J Exp Med 1992;175:377-85.
9. Valenta R, Vrtala S, Ebner C, Kraft D, Scheiner O. Diagnosis of grass pollen allergy with recombinant timothy grass (Phleum pratense) pollen allergens. Int Arch Allergy Immunol 1992;97:287-94.
10. Ferreira FD, Hoffmann-Sommergruber K, Breiteneder H, Pettenburger K, Ebner C, Sommergruber W, Steiner R, Bohle B, Sperr WR, Valent P, Kungl AJ, Breitenbach M, Kraft D, Scheiner O. Purification and characterization of recombinant Bet v 1, the major birch pollen allergen. J Biol Chem 1993;268:19574-80.
11. Vrtala S, Sperr WR, Reimitzer I, vanRee R, Laffer S, Müller W-D, Valent P, Lechner K, Rumpold H, Kraft D, Scheiner O, Valenta R. cDNA cloning of a major allergen from timothy grass (Phleum pratense) pollen; characterization of the recombinant Ph1 p 5 allergen. J Immunol 1993;151:4773-81.
12. Valenta R, Ferreira F, Grote M, Swoboda I, Vrtala S, Duchêne M, Deviller P, Meagher RB, McKinney E, Heberle-Bors E, Kraft D, Schemer O. Identification of profilin as an actin-binding protein in higher plants. J Biol Chem 1993;268:22777-81.
13. Valenta R, Duchêne M, Vrtala S, Ball T, Ferreira F, Laffer S, Hirschwehr R, Ebner C, Sperr WR, Valent P, Kraft D, Scheiner O. Recombinant allergens as candidates for immunotherapy of type I allergic diseases. In: Chanock RM, Ginsberg HS, Brown F, Lerner R, eds. Vaccines. New York: Cold Spring Harbor Laboratory Press, 1993;37-42.
14. Sakaguchi M, Inouye S, Imaoka K, Miyazawa H, Hashimoto M, Nigi H, Nakamura S, Gotoh S, Minezawa M, Fujimoto K, Honjo S, Taniguchi Y, Ando S. Measurement of serum IgE antibodies against Japanese cedar pollen (Cryptomerica japonica) in Japanese monkeys (Macaco fuscata) with pollinosis. J Med Primatol 1992; 21:323-7.
15. Halpern GM, Stewart J, Gershwin L, Gonzales G. Respiratory allergy in a chimpanzee. Evaluation by skin testing and in vitro FAST assays. Ann Allergy 1989;62: 255-61.
16. Ishizaka K, Ishizaka T, Tada T. Immunoglobulin E in the monkey. J Immunol 1969;103:445-56.
17. Girard JP, Hampai A. Production of reaginic antibody in monkeys following immunization with dialyzable constituents of timothy pollen extracts. Int Arch Allergy Appl Immunol 1970;37:561-70.
18. Chiba N, Tamura T, Koizumi K, Tanigawa M, Shiba M. Experimental cedar pollinosis in rhesus monkeys. Int Arch Allergy Appl Immunol 1990;93:83-90.
19. Valenta R, Duchêne M, Pettenburger K, Sillaber C, Valent P, Bettelheim P, Breitenbach M, Rumpold H, Kraft D, Scheiner O. Identification of profilin as a novel pollen allergen; IgE autoreactivity in sensitized individuals. Science 1991;253:557-60.
20. Jarolim E, Rumpold H, Endler AT, Ebner H, Scheiner O, Kraft D. IgE and IgG antibodies of patients with allergy to birch as tools to define the allergen profile of Betula verrucosa. Allergy 1989;44:385-95.
21. Ebner C, Birkner T, Valenta R, Rumpold H, Breitenbach M, Scheiner O, Kraft D. Common epitopes of birch pollen and apples - studies by Western and Northern blot. J ALLERGY CLIN IMMUNOL 1991;88:588-94.
22. Hirschwehr R, Valenta R, Ebner C, Ferreira F, Sperr WR, Valent P, Rohac M, Rumpold H, Scheiner O, Kraft D. Identification of common allergenic structures in hazel pollen and hazelnuts: a possible explanation for sensitivity to hazelnuts in patients allergic to tree pollen. J ALLERGY CLIN IMMUNOL 1992;90:927-36.
23. Vallier P, Dechamp C, Valenta R, Vial O, Deviller P. Purification and characterization of an allergen from celery immunochemically related to an allergen present in several other plant species. Clin Exp Allergy 1992;22:774-82.
24. van Ree R, Voitenko V, Leeuwen WA, Aalberse RC. Profilin is a cross-reactive allergen in pollen and vegetable foods. Int Arch Allergy Immunol 1992;98:97-104.
25. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:680-85.
26. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979;76:4350-4.
27. Valent P, Besemer J, Muhm M, Majdic O, Lechner K, Bettelheim P. Interleukin 3 activates human blood basophils via high-affinity binding sites. Proc Natl Acad Sci USA 1989;86:5542-6.
28. Ebner C, Szepfalusi Z, Ferreira F, Jilek A, Valenta R, Parronchi P, Maggi E, Romagnani S, Scheiner O, Kraft D. Identification of multiple T cell epitopes on Bet v 1, the major birch pollen allergen, using specific T cell clones and overlapping peptides. J Immunol 1993;150:1047-54.
29. Perper RS, Sanda M, Lichtenstein LM. Int Arch Allergy Immunol 1972;43:837-46.
30. Valenta R, Ball T, Vrtala S, Duchêne M, Kraft D, Scheiner O. cDNA cloning and expression of timothy grass (Phleum pratense) pollen profilin in Escherichia coli: comparison with birch pollen profilin. Biochem Biophys Res Comm 1994;199:106-18.
31. Sutton BJ, Gould HJ. The human IgE network. Nature 1993;366:421-4.
32. Scheiner O, Bohle B, Breitenbach M, Breiteneder H, Duchêne M, Ebner C, Ferreira F, Hirschwehr R, Hoffmann-Sommergruber K, Pettenburger K, Rumpold H, Steiner R, Tejkl M, Valenta R, Kraft D. Advances in Allergology and Clinical Immunology. Carnforth: Parthenon Publishing Group, 1992;115-26.
33. Valenta R, Duchêne M, Vrtala S, Ball T, Ferreira F, Laffer S, Hirschwehr R, Ebner C, Sperr W, Valent P, Kraft D, Scheiner O. Vaccines, New York: Cold Spring Harbor Laboratory Press, 1993;37-42.
34. Valenta R, Breiteneder H, Pettenburger K, Breitenbach M, Rumpold H, Kraft D, Scheiner O. Homology of the major birch-pollen allergen, Bet v 1, with the major pollen allergens of alder, hazel, and hornbeam at the nucleic acid level as determined by cross-hybridization. J ALLERGY CLIN IMMUNOL 1991;87:677-82.
35. Rohac M, Birkner T, Reimitzer I, Bohle B, Steiner R, Breitenbach M, Kraft D, Scheiner O, Gabl F, Rumpold H. The immunological relationship of epitopes on major tree pollen allergens. Mol Immunol 1991;8:897-906.
36. Breiteneder H, Ferreira F, Reikerstorfer A, Duchêne M, Valenta R, Hoffmann-Sommergruber K, Ebner C, Breitenbach M, Kraft D, Scheiner O. Complementary DNA cloning and expression in Escherichia coli of Ata g I, the major allergen in pollen of alder (Alnus glutinosa). J ALLERGY CLIN IMMUNOL 1992;90:909-17.
37. Breiteneder H, Ferreira F, Hoffmann-Sommergruber K, Ebner C, Breitenbach M, Rumpold H, Kraft D, Scheiner O. Four recombinant isoforms of Cor a I, the major allergen of hazel pollen, show different IgE-binding properties. Eur J Biochem 1993;212:355-62.
38. Valenta R, Sperr WR, Ferreira F, Valent P, Sillaber C, Tejkl M, Duchêne M, Ebner C, Lechner K, Kraft D, and Scheiner O. Induction of specific histamine release with purified natural and recombinant birch pollen allergens. J ALLERGY CLIN IMMUNOL 1993;91:88-97.