Use of recombinant antigens of Borrelia burgdorferi in serologic tests for diagnosis of Lyme borreliosis

Journal of Clinical Microbiology

Volumn 34, Issue 2, 1996, Pages 237-240

  Magnarelli, Louis A ^a   Fikrig, Erol ^b   Padula, Steven J ^c,d   Anderson, John F ^a   Flavell, Richard A ^a  

^a The Connecticut Agricultural Experiment Station   (United States)

^b Section of Rheumatology   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; FLAGELLIN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; RECOMBINANT PROTEIN;

ANTIBODY TITER; ARTICLE; BORRELIA BURGDORFERI; CLINICAL ARTICLE; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHEMA CHRONICUM MIGRANS; HUMAN; LYME DISEASE; NONHUMAN; PERIODONTITIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SERODIAGNOSIS; SYPHILIS;

BACTERIA (MICROORGANISMS); BORRELIA; BORRELIA BURGDORFERI; SPIROCHAETALES;

EID: 0030027291     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/jcm.34.2.237-240.1996     Document Type: Article

References (28)

1. Aguero-Rosenfeld, M. E., J. Nowakowski, D. F. McKenna, C. A. Carbonaro, and G. P. Wormser. 1993. Serodiagnosis in early Lyme disease J. Clin. Microbiol. 31:3090-3095.
2. Anderson, J. F., L. A. Magnarelli, W. Burgdorfer, and A. G. Barbour. 1983 Spirochetes in kodes dammini and mammals from Connecticut Am. J. Trop. Med. Hyg. 32:818-824.
3. Dattwyler, R. J., D. J. Volkman, B. J. Luft, J. J. Halperin, J. Thomas, and M. G. Golightly. 1988. Seronegative Lyme disease. Dissociation of specific T- and B- lymphocyte responses to Borrelia burgdorferi. N. Engl J Med. 319: 1441-1446.
4. Dressler, F., J. A. Whalen, B. N. Reinhardt, and A. C. Steere. 1993. Western blotting in the serodiagnosis of Lyme disease. J Infect. Dis. 167:392-400.
5. Engstrom, S. M., E. Shoop, and R. C. Johnson. 1995. Immunoblot interpretation criteria for serodiagnosis of early Lyme disease. J. Clin. Microbiol 33: 419-427
6. Fikrig, E., S. W. Barthold, F. S. Kantor, and R. A. Flavell. 1990. Protection of mice against the Lyme disease agent by immunizing with recombinant OspA. Science 250:553-556.
7. Fikrig, E., S. W. Barthold, N. Marcantonio, K. DePonte, F. S. Kantor, and R. A. Flavell. 1992. Roles of OspA, OspB, and fiagellin in protective immunity to Lyme borreliosis in laboratory mice. Infect Immun. 60:657-661.
8. Fuchs, R., S. Jauris, F. Lottspeich, V. Preac-Mursic, B. Wilske, and E. Soutschek. 1991. Molecular analysis and expression of a Borrelia burgdorferi gene encoding a 22kDa protein (pC) in Escherichia coli. Mol. Microbiol. 6: 503-509.
9. Fung, B. P., G. L. McHugh, J. M. Leong, and A. C. Steere. 1994. Humoral immune response to outer surface protein C of Borrelia burgdorferi in Lyme disease: role of immunoglobulin M response in the serodiagnosis of early infection. Infect. Immun. 62:3213-3221
10. Gerber, M. A., E. D. Shapiro, G. L. Bell, A. Sampieri, and S. J. Padula. 1995. Recombinant outer surface protein C ELISA for the diagnosis of early Lyme disease. J Infect. Dis. 171:724-727.
11. Karlsson, M., I. Mollegard, G. Stiernstedt, A. M. Henriksson, and B. Wretlind. 1988. Characterization of antibody response in patients with Borrelia meningitis. Serodiag. Immunother. Infect. Dis. 2:375-386.
12. Lam, T. T., T.-P. K. Nguyen, R. R. Montgomery, F. S. Kantor, E. Fikrig, and R. A. Flavell. 1994. Outer surface proteins E and F of Borrelia burgdorferi, the agent of Lyme disease. Infect. Immun. 62:290-298.
13. Luft, B. J., S. Mudri, W. Jiang, R. J. Dattwyler, P. D. Gorevic, T. Fischer, P. Munoz, J. J. Dunn, and W. H. Schubach. 1992. The 93-kilodalton protein of Borrelia burgdorferi: an immunodominant protoplasmic cylinder antigen. Infect. Immun. 60:4309-1321.
14. Ma, B., B. Christen, D. Leung, and C. Vigo-Pelfrey. 1992 Serodiagnosis of Lyme borreliosis by Western immunoblot. reactivity of various significant antibodies against Borrelia burgdorferi. J. Clin. Microbiol. 30:370-376.
15. Magnarelli, L. A., and J. F. Anderson. 1988. Enzyme-linked immunosorbent assays for the detection of class-specific immunoglobulins to Borrelia burgdorferi. Am. J. Epidemiol. 127:818-825.
16. Magnarelli, L. A., and J. F. Anderson. 1991. Adsorption and biotin-streptavidin amplification in serologic tests for diagnosis of Lyme borreliosis. J. Clin Microbiol. 29:1761-1764.
17. Magnarelli, L. A., J. F. Anderson, and A. G. Barbour. 1989. Enzyme-linked immunosorbent assays for Lyme disease: reactivity of subunits of Borrelia burgdorferi. J. Infect. Dis. 159:43-49.
18. Magnarelli, L. A., J. F. Anderson, and R. C. Johnson. 1987. Cross-reactivity in serologic tests for Lyme disease and other spirochetal infections. J. Infect. Dis. 156:183-188.
19. Magnarelli, L. A., E. Fikrig, R. Berland, J. F. Anderson, and R. A. Flavell. 1992 Comparison of whole cell antibodies and an antigenic flagellar epitope of Borrelia burgdorferi in serologic tests for diagnosis of Lyme borreliosis. J. Clin. Microbiol. 30:3158-3162.
20. Magnarelli, L. A., J. N. Miller, J. F. Anderson, and G. R. Riviere. 1990 Cross-reactivity of nonspecific treponemal antibody in serologic tests for Lyme disease. J. Clin. Microbiol. 28:1276-1279.
21. Nguyen, T.-P. K., T. T. Lam, S. W. Barthold, S. R. Telford III, R. A. Flavell, and E. Fikrig. 1994. Partial destruction of Borrelia burgdorferi within ticks that engorged on OspE- or OspF-immunized mice Infect. Immun. 62:2079-2084.
22. Padula, S. J., F. Dias, A. Sampieri, R. B. Craven, and R. W. Ryan. 1994 Use of recombinant OspC from Borrelia burgdorferi for serodiagnosis of early Lyme disease. J. Clin. Microbiol. 32:1733-1738.
23. Padula, S. J., A. Sampieri, F. Dias, A. Szezepanski, and R. W. Ryan. 1993. Molecular characterization and expression of p23 (OspC) from a North American strain of Borrelia burgdorferi. Infect. Immun. 61:5097-5105.
24. Shrestha, M., R. L. Grodzicki, and A. C. Steere. 1985 Diagnosing early Lyme disease Am. J. Med. 78:235-240.
25. Simpson, W. J., M. E. Schrumpf, and T. G. Schwan. 1990 Reactivity of human Lyme borreliosis sera with a 39-kilodalton antigen specific to Borrelia burgdorferi. J. Clin. Microbiol 28:1329-1337
26. Steere, A. C. 1989 Lyme disease. N. Engl J. Med. 321:586-596.
27. Wilske, B., V. Preac-Mursic, G. Schierz, and K. V. Busch. 1986. Immunochemical and immunological analysis of European Borrelia burgdorferi strains. Zentralbl. Bakteriol. Mikrobiol. Hyg. Ser. A 263:92-102
28. Wilske, B., G. Schierz, V. Preac-Mursic, K. Von Busch, R. Kuhbeck, H.-W. Pfister, and K. Einhaupl. 1986. Intrathecal production of specific antibodies against Borrelia burgdorferi in patients with lymphocytic meningoradiculitis (Bannwarth's syndrome). J. Infect, Dis. 153:304-314.