In vitro production of stable Epstein-Barr virus-positive epithelial cell clones which resemble the virus:cell interaction observed in nasopharyngeal carcinoma

Virology

Volumn 215, Issue 1, 1996, Pages 40-50

  Knox, Pauline G ^a   Li, Qing Xue ^a   Rickinson, Alan B ^a   Young, Lawrence S ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; EPSTEIN BARR VIRUS; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS REPLICATION;

EID: 0030026901     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0005     Document Type: Article

References (55)

1. Adams, J. C., and Watt, F. M. (1989). Fibronectin inhibits the terminal differentiation of human keratinocytes. Nature 340, 307-309.
2. Allday, M. J., and Crawford, D. H. (1988). Role of epithelium in EBV persistence and pathogenesis of B-cell tumours. Lancet 1, 855-857.
3. Baer, R., Bankier, A. T., Biggin, M. D., Deininger, P. L., Farrell, P. J., Gibson, T. G., Hatfull, G., Hudson, G. S., Satchwell, S. C., Seguin, C., Tuffnel, P. S., and Barrell, B. G. (1984). DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature 310, 207-211.
4. Brooks, L., Yao, Q. Y., Rickinson, A. B., and Young, L. S. (1992). Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: Coexpression of EBNA1, LMP1,and LMP2 transcripts. J. Virol. 66, 2689-2697.
5. Brooks, L. A., Lear, A. L., Young, L. S., and Rickinson, A. B. (1993). Transcripts from the Epstein-Barr virus BamHI A fragment are detectable in all three forms of virus latency. J. Virol. 67, 3182-3190.
6. Chen, F., Hu, L-F., Ernberg, I., Klein, G., and Winberg, G. (1995). Coupled transcription of Epstein-Barr virus latent membrane protein (LMP)-1 and LMP-2B genes in nasopharyngeal carcinomas. J. Gen. Virol. 76, 131-138.
7. Crawford, D. H., and Ando, I. (1986). Epstein-Barr virus induction is associated with B-cell maturation. Immunology 59, 405-409.
8. Dawson, C. D., Rickinson, A. B., and Young, L. S. (1990). Epstein-Barr virus latent membrane protein inhibits epithelial cell differentiation. Nature 344, 777-780.
9. Deacon, E. M., Pallesen, G., Niedobitek, G., Crocker, J., Brooks, L., Rickinson, A. B., and Young, L. S. (1993). Epstein-Barr virus and Hodgkin's disease: Transcriptional analysis of virus latency in the malignant cells. J. Exp. Med. 177, 339-349.
10. Dover, R., and Watt, F. M. (1987). Measurement of the rate of epidermal terminal differentiation: Expression of involucrin by S-phase keratinocytes in culture and in psoriatic plaques. J. Invest. Dermatol. 89, 349-352.
11. Fåhraeus, R., Li-Fu, H., Ernberg, I., Finke, J., Rowe, M., Klein, G., Falk, K., Nilsson, E., Yadaf, M., Busson, P., Tursz, T., and Kallin, B. (1988). Expression of the Epstein-Barr virus genome in nasopharyngeal carcinoma. Int. J. Cancer 42, 329-338.
12. Flemington, E., and Speck, S. H. (1990). Identification of phorbol ester elements in the promotor of Epstein-Barr virus putative lytic switch gene BZLF1. J. Virol. 64, 1217-1226.
13. Gardella, T., Medveczky, P., Sairenji, T., and Mulder, C. (1984). Detection of circular and linear herpesvirus DNA molecules in mammalian cells by gel electrophoresis. J. Virol. 50, 248-254.
14. Gilligan, K., Rajadurai, P., Resnick, L., and Raab-Traub, N. (1990a). Epstein-Barr virus small nuclear RNAs are not expressed in permissively infected cells in AIDS-associated leukoplakia. Proc. Natl. Acad. Sci. USA 87, 8790-8794.
15. Gilligan, K., Sato, H., Rajadurai, P., Busson, P., Young, L., Rickinson, A., Tursz, T., and Raab-Traub, N. (1990b). Novel transcription from the Epstein-Barr virus terminal EcoRI fragment, DIJhet, in anasopharyngeal carcinoma. J. Virol. 64, 4948-4956.
16. Glaser, R., and Rapp, F. (1972). Rescue of Epstein-Barr virus from somatic cell hybrids of Burkitt lymphoblastoid cells. J. Virol. 10, 288-296.
17. Gratama, J. W., Oosterveer, M. A. P., Zwaan, F. E., Lepoutre, J., klein, G., and Ernberg, I. (1988). Eradication of Epstein-Barr virus by allogeneic bone marrow transplantation: Implications for sites of viral latency. Proc. Natl. Acad. Sci. USA 85, 8693-8696.
18. Greenspan, J. S., Greenspan, D., Lennette, E. T., Abrams, D. I., Canant, M. A., Petersen, V., and Freese, U. K. (1985). Replication of Epstein-Barr virus within the epithelial cells of oral hairy leukoplakia, an AID-associated lesion. N. Engl. J. Med. 313, 1564-1571.
19. Gregory,C. D., Rowe, M., and Rickinson, A. B. (1990). Different Epstein-Barr virus (EBV)-B cell interactions in phenotypically distinct clones of a Burkitt lymphoma cell line. J. Gen. Virol. 71, 1481-1495.
20. Hitt, M. M., Allday, M. J., Hara, T., Karran, L., Jones, M. D., Busson, P., Tursz T., Ernberg, I., and Griffin, B. E. (1989). EBV gene expression in an NPC-related tumour. EMBO J. 8, 2639-2651.
21. Howe, J. G., and Steitz, J. A. (1986). Localisation of Epstein-Barr virus-encoded small RNAs by in situ hybridisation. Proc. Natl. Acad. Sci. USA 83, 9006-9010.
22. Kenney, S., and Zalani, S. (1995). Regulation of BZLF1 function by viral and host cell factors. Epstein-Barr Virus Rep. 2, 23-28.
23. Kerr, B. M., Lear, A. L., Rowe, M., Groom-Carter, D., Young, L. S., Rookes, S. M., Gallimore, P. H., and Rickinson, A. B. (1992). Three transcriptionally distinct forms of Epstein-Barr virus latency in somatic cell hybrids: Cell phenotype dependence of virus promotor usage. Virology 187, 189-201.
24. Kieff, E., and Leibowitz, D. (1990). Epstein-Barr virus and its replication. In "Fields Virology" (B. N. Fields and D. M. Knipe, Eds.), 2nd ed., pp. 1889-1920. Raven Press, New York.
25. Laux, G., Economou, A., and Farrell, P. (1989). The terminal protein gene 2 of Epstein-Barr virus is transcribed from a bidirectional latent promoter region. J. Gen. Virol. 70, 3079-3084.
26. Li, Q. X, Young, L. S., Niedobitek, G., Dawson, C. W., Birkenbach, M., Wang, F., and Rickinson, A. B. (1992). Epstein-Barr virus infection and replication in a human epithelial cell system. Nature 356, 347-350.
27. Magrath, I., Jain, V., and Bhatia, K. (1993). Molecular epidemiology of Burkitt's lymphoma. Epstein-Barr Virus Assoc. Dis. 225, 377-396.
28. Manet, E., Gruffat, H., Trescol-Biemont, M. C., Moreno, I., Chambard, P., Giot, J. F., and Sergeant, A. (1989). Epstein-Barr virus bicistronic mRNAs generated by facultative splicing code for two transcriptional trans-activators. EMBO J. 8, 1819-1826.
29. Miller, G. (1990). Epstein-Barr virus: Biology, pathogenesis, and medical aspects. In "Fields Virology" (B. N. Fields and D. M. Knipe, Eds.), 2nd ed., pp. 1921-1958. Raven Press, New York.
30. Niedobitek, G., and Young, L. S. (1994). Epstein-Barr virus persistence and virus-associated tumours. Lancet 343, 333-335.
31. Niedobitek, G., Young, L. S., Lau, R., Brooks, L., Greenspan, D., Greenspan, J. S., and Rickinson, A. B. (1991). Epstein-Barr virus infection in oral hairy leukoplakia: Virus replication in the absence of a detectable latent phase. J. Gen. Virol. 72, 3035-3046.
32. Niedobitek, G., Young, L. S., Sam, C. K., Brooks, L., Prasad, U., and Rickinson, A. B. (1992). Expression of Epstein-Barr virus genes and of lymphocyte activation molecules in undifferentiated nasopharyngeal carcinomas. Am. J. Pathol. 140, 879-887.
33. Nonkwelo, C., Henson, E. B. D., and Sample, J. (1995). Characterization of the Epstein-Barr virus Fp promoter. Virology 206, 183-195.
34. Poirier, S., Ohshima, H., de-The, G., Hubert, A., Bourgade, M. C., and Bartsch, H. (1987). Volatile nitrosamine levels in common foods from Tunisia, South China and Greenland, high-risk areas for nasopharyngeal carcinoma. Int. J. Cancer 33, 293-296.
35. Raab-Traub, N. (1992). Epstein-Barr virus and nasopharyngeal carcinoma. Semin. Cancer Biol. 3, 297-307.
36. Raab-Traub, N., and Flynn, K (1986). The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation. Cell 47, 883-889.
37. Reedman, B. M., and Klein, G. (1973). Cellular localisation of an Epstein-Barr virus (EBV)-associated complement fixing antigen in producer and non-producer lymphoblastoid cell lines. Int. J. Cancer 11, 499-520.
38. Rickinson, A. B., Yao, Q. Y., and Wallace, L. E. (1985). The Epstein-Barr virus as a model of virus-host interactions. Br. Med. Bull. 41, 75-79.
39. Rowe, M., Evans, H. S., Young, L. S., Hennessy, K., Kieff, E., and Rickinson, A. B. (1987a). Monoclonal antibodies to the latent membrane protein of Epstein-Barr virus reveal heterogeneity of the protein and inducible expression in virus-transformed cells. J. Gen. Virol. 68, 1575-1586.
40. Rowe, M., Rowe, D. T., Gregory, C. D., Young, L. S., Farrell, P. J., Rupani, H., and Rickinson, A. B. (1987b). Differences in B cell growth pheno-type reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma. EMBO J. 6, 2743-2751.
41. Sample, J., Brooks, L., Sample, C., Young, L., Rowe, M., Gregory, C., Rickinson, A., and Kieff, E. (1991). Restricted Epstein-Barr virus protein expression in Burkitt lymphoma is due to a different Epstein-Barr nuclear antigen-1 transcriptional initiation site. Proc. Natl. Acad. Sci. USA 88, 6343-6347.
42. Schaeffer, B. C., Woisetschlaeger, M., Strominger, J. L., and Speck, S. H. (1991). Exclusive expression of Epstein-Barr virus nuclear antigen 1 in Burkitt lymphoma arises from a third promoter, distinct from the promoters used in latently infected lymphocytes. Proc. Natl. Acad. Sci. USA 88, 6550-6554.
43. Shibata, D., and Weiss, L. M. (1992). Epstein-Barr virus-associated gastric adenocarcinoma. Am. J. Pathol. 140, 769-774.
44. Sixbey, J. W., Nedrud, J. G., Raab-Traub, N., Hanes, R. A., and Pagano, J. S. (1984). Epstein-Barr virus replication in oropharyngeal epithelial cells. N. Engl. J. Med. 310, 1225-1230.
45. Sixbey, J. W., Vesterinen, E., Nedrud, J. G., Raab-Traub, N., Walton, L. A., and Pagano, J. S. (1983). Replication of Epstein-Barr virus in human epithelial cells infected in vitro. Nature 306, 480-483.
46. Speck, S. H., and Strominger, J. L. (1989). Transcription of Epstein-Barr virus in latently infected, growth-transformed lymphocytes. Adv. Viral Oncol. 8, 133-150.
47. Takimoto, T., Ogura, H., Sato, H., Umeda, R., and Hatano, M. (1985). Isolation of transforming and early antigen-inducing Epstein-Barr virus from nasopharyngeal carcinoma hybrid cells (NPC-KT). J. Natl. Cancer Inst. 74, 57-59.
48. Thomas, J. A., Allday, M., and Crawford, D. H. (1991). Epstein-Barr virus-associated lymphoproliferative disorders in immunocompromised individuals. Adv. Cancer Res. 57, 329-380.
49. Vidal, M., Wrighton, C., Eccles, S., Burke, J., and Grosveld, F. (1990). Differences in human cell lines to support stable replication of Epstein-Barr virus-based vectors. Biochim. Biophys. Acta 1048, 171-177.
50. Wendel-Hansen, V., Rosén, A., and Nein, G. (1987). EBV-transformed lymphoblastoid cell lines down-regulate EBNA in parallel with secretory differentiation. Int. J. Cancer 39, 404-408.
51. Wendel-Hansen, V., Tao, W., Ericson, M., Klein, G., and Rosen, A. (1992). Cell phenotype (CD23)-dependent variation in EBV genome copy numbers within lymphoblastoid cell lines (LCL). Int. J. Cancer 50, 589-592.
52. Young, L., Alfieri, C., Hennessey, K., Evans, H., OHara, C., Anderson, K. C., Ritz, J., Shapiro, R. S., Rickinson, A., Kieff, E., and Cohen, J. I. (1989). Expression of Epstein-Barr virus transformation-associated genes in tissues of patients with EBV lymphoproliferative disease. N. Engl. J. Med. 321, 1080-1085.
53. Young, L., Dawson, C., Clark, D., Rupani, H., Busson, P., Tursz, T., Johnson, A., and Rickinson, A. (1988). Epstein-Barr virus gene expression in nasopharyngeal carcinoma. J. Gen. Virol. 69, 1051-1065.
54. Young, L. S., Lau, R., Rowe, M., Niedobitek, G., Packham, G., Shanaham, F., Rowe, D. T., Greenspan, D., Greenspan, J. S., Rickinson, A. B., and Farrell, P. J. (1991). Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral "hairy" leukoplakia. J. Virol. 65, 2868-2874.
55. Young, L. S., and Rowe, M. (1992). Epstein-Barr virus, lymphomas and Hodgkin's disease. Semin. Cancer Biol. 3, 273-284.