Aging of the brain-testicular axis: Reproductive systems of healthy old male rats with or without endocrine stimulation (43953)

Experimental Biology and Medicine

Volumn 211, Issue 1, 1996, Pages 69-75

  Taylor, George ^a   Bardgett, Mark ^a,b   Farr, Susan ^a   Humphrey, William ^a   Womack, Sharon ^a   Weiss, Juergen ^c  

^a UNIVERSITY OF MISSOURI ST LOUIS   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOCRINE FUNCTION; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; MALE; NONHUMAN; RAT; REPRODUCTION; SEXUAL FUNCTION; TESTIS;

AGING; ANIMALS; BEHAVIOR, ANIMAL; FEMALE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; RATS; RATS, WISTAR; TESTIS; TESTOSTERONE;

ANIMALIA;

EID: 0030026890     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Vom Saal F, Finch C, Nelson J. Natural history and mechanisms of reproductive aging in human, laboratory rodents, and other selected vertebrates. In: Knobil E, Neill J, Eds. The Physiology of Reproduction, New York: Raven Press, Vol 2:pp1213-1314, 1994.
2. Harman SM, Tsitouras PD. Reproductive hormones in aging men. I. Measurement of sex steroids, basal luteinizing hormone, and Leydig cell response to human chorionic gonadotropin. J. Clin Endocrinol Metab 51:35-40, 1980.
3. Nieschlag E, Lammers U, Freischem C, Wickings E. Reproductive functions in young fathers and grandfathers. J Clin Endocrinol Metab 55:676-681, 1982.
4. 57BL/6NNia mice. J Gerontol 43:79-84, 1988.
5. Harman SM, Talbert GB. Reproductive aging. In: Finch C, Schneider E, Eds. Handbook of the Biology of Aging. New York: Van Nostrand Publishers, pp457-510, 1985.
6. Vom Saal F, Finch CE. Physiology of aging. In: Knobil E, Neill J, Eds. Physiology of Reproduction. New York: Raven Press, pp2351-2413, 1988.
7. Brown WA, Monti P, Corriveau D. Serum testosterone and sexual activity and interest in men. Arch Sex Behav 7:97-103, 1978.
8. Kinoshita Y, Higashi Y, Winters S, Shima H, Troen P. An analysis of age-related decline in testicular steroidogenesis in the rat. Biol Reprod 32:309, 1985.
9. Schiavi R, White D, Mandeli J. Pituitary-gonadal function during sleep in healthy aging men. Psychoneuroendocrinology 17:599-609, 1992.
10. Coquelin A, Desjardins C. Luteinizing hormone and testosterone secretion in young and old male mice. Am J Physiol 243:E257-E263, 1982.
11. Bedrak E, Chap Z, Brown R. Age-related changes in the hypothalamic-pituitary-testicular function of the rat. Exp Gerontol 18:95-104, 1983.
12. Tenover J, Matsumoto A, Clifton D, Bremner W. Age-related alterations in the circadian rhythms of pulsatile luteinizing hormone and testosterone secretion in healthy men. J Gerontol 43:M163-M169, 1988.
13. Johnson L, May M, Busbee D, Williams JD. Effect of age and dietary restriction on daily sperm production and number and transit time of epididymal spermatozoa in the mouse. Ag 15:65-72, 1992.
14. Taylor GT, Scherrer J, Weiss J, Pitha J. Endocrine interactions: Adrenal steroids and precursors. Am J Physiol 266:E676-E681, 1994.
15. Garcia-Segura L, Perez J, Jones E, Naftolin F. Loss of sexual dimorphism in rat arcuate nucleus neuronal membranes with reproductive aging. Exp Neurol 112:125-128, 1991.
16. Swerdloff R, Wang C, Hines M, Gorski R. Effect of androgens on the brain and other organs during development and aging. Psychoneuroendocrinology 17:375-383, 1992.
17. Davidson JM, Gray GD, Smith ER. The sexual psychoendocrinology of aging. In: Meites J, Ed. Neuroendocrinology of Aging. New York: Plenum Press, pp221-258, 1983.
18. Spruijt B, Meyerson B, Hoglund U. Aging and sociosexual behavior in the male rat. Behav Brain Res 32:51-62, 1989.
19. Huber M, Bronson FH. Desjardins C. Sexual activity of aged male mice: Correlation with level of arousal, physical endurance, pathological status and ejaculation capacity. Biol Reprod 23:305-316, 1980.
20. Taylor GT, Bardgett M, Farr S, Womack S, Komitowski D, Weiss J. Steroidal interactions in the ageing endocrine system: Absence of suppression and pathology in reproductive systems of old males from a mixed-sex, socially stressful rat colony. J Endocrinol 137:115-122, 1993.
21. Craigen W, Bronson F. Deterioration of the capacity for sexual arousal in aged male mice. Biol Reprod 26:869-874, 1982.
22. Gray A, Feldman H, McKinlay J, Longscope C. Age, disease, and changing sex hormone levels in middle-aged men: Results of the Massachusetts male aging study. J Clin Endocrinol Metab 73:1016-1025, 1991.
23. Ottenweller J, Tapp W, Creighton D, Natelson B. Aging, stress and chronic disease interact to suppress plasma testosterone in Syrian hamsters. J Gerontol 43:M175-M180, 1988.
24. Playmate S, Tenover JS, Bremner W. Circadian variation in testosterone, sex hormone-binding globulin, and calculated non-sex hormone-binding globulin bound testosterone in healthy young and elderly men. J Androl 10:366-371, 1989.
25. Wilson CA. Pharmacological targets for the control of male and female sexual behaviour. In: Riley AJ, Peet M, Wilson CA, Eds. Sexual Pharmacology. Oxford: Oxford Medical Publications, pp1-58, 1993.
26. Taylor GT, Komitowski D, Muto S, Weiss J. Behavioral endocrinology of male rats with periodic sexual contacts with exclusive or varied females. Proc Soc Exp Biol Med 192:236-241, 1989.
27. Sachs BD, Meisel RL. The physiology of male reproductive behavior. In: Knobil E, Neill J, Eds. The Physiology of Reproduction, New York: Raven Press, Vol 2:pp3-106, 1994.
28. Taylor GT, Haller J, Rupich R, Weiss J. Testicular hormones and intermale aggressive behaviour in the presence of a female rat. J Endocrinol 100:315-321, 1984.
29. Taylor GT, Regan D, Haller J. Sexual experience, androgens, and female choice of a mate in laboratory rats. J Endocrinol 96:43-52, 1983.
30. Taylor GT, Weiss J, Frechmann T. Ontogeny of epididymal sperm reserves during the reproductive lifespan of rats after previous sexual experiences. J Reprod Fertil 77:419-423, 1986.
31. Komitowski D, Muto S, Weiss J, Schmitt B, Taylor GT. Structural changes in nuclear chromatin in rat pituitary after chronic stress of low intensity. Anat Rec 220:125-131, 1988.
32. Bronson FH, Desjardins C. Relative effects of exercise, diet and female stimulation on sexual aging of male mice. J Gerontol 37:555-559, 1982.
33. Smith ER, Stefanick M, Clark JT, Davidson JM. Hormones and sexual behavior in relationship to aging in male rats. Horm Behav 26:110-135, 1992.
34. Phoenix C, Chambers K. Testosterone therapy in young and old rhesus males that display low levels of sexual activity. Physiol Behav 43:479-484, 1988.
35. Brabant G, Prank K, Schofl C. Pulsatile patterns in hormone secretion. Trends Endocrinol Metab 3:183-189, 1992.
36. Gray GD, Smith E, Dorsa D, Davidson JM. Sexual behavior and testosterone in middle-aged rats. Endocrinology 109:1597-1604, 1981.
37. Hsu HK, Hsu C, Yu JYC, Peng MT. Aging, sexual behavior and endocrinology. Gerontol 32:10-17, 1986.
38. Johnson L, Neaves WB. Enhanced daily sperm production in the remaining testis of aged rats following hemicastration. J Androl 4:162-166, 1983.
39. Kaler L, Neaves W. The steroidogenic capacity of the aging rat testis. J Gerontol 36:398-404, 1981.
40. Bronson F, Desjardins C. Endocrine responses to sexual arousal in male mice. Endocrinol 111:1286-1291, 1982.
41. Sachs BD, Leipheimer RE. Rapid effect of testosterone on striated muscle activity in rats. Neuroendocrinology 48:453-458, 1988.
42. Frankel AI, Mock EJ. Time course of hormonal response to sexual behavior in aging male rats. Exp Gerontol 16:363-369, 1981.
43. Schoultz B, Carlstrom K, Collste L, Eriksson A, Henriksson P, Pousette A, Stege R. Estrogen therapy and liver function: Metabolic effects of oral and parenteral administration. Prostate 14:389-395, 1989.
44. Seifritz E, Hemmeter U, Poldinger W, Froesch E, Reul J, Holsboer-Trachsler E. Differential mood response to natural and synthetic corticosteroids after bilateral adrenalectomy: A case report. J Psychiat Res 28:7-12, 1994.
45. Bronson FH, Rissman EF. Epinephrine release in response to sexual activity in male versus female rats. Physiol Behav 45:185-189, 1989.
46. Taylor GT, Weiss J, Frechmann T, Haller J. Copulation induces an acute increase in epididymal sperm numbers in rats. J Reprod Fertil 73:323-327, 1985.
47. Taylor GT. Natural selection and the endocrinology of prostatic cancer: Aging's debts from a fit youth. Growth Develop Aging 54:3-5, 1990.
48. Hirano K, Yamada H. Studies on the absorption of practically water-insoluble drugs following injection: IV. An approach for predicting relative intramuscular absorption rates of a drug in oily solution, aqueous suspension and aqueous surfactant solution in rat. Chem Pharm Bull 29:1410-1415, 1981.