Ionophore properties of monensin derivatives studied on human erythrocytes by 23Na NMR and K+ and H+ potentiometry: Relationship with antimicrobial and antimalarial activities

Journal of Medicinal Chemistry

Volumn 39, Issue 2, 1996, Pages 588-595

  Rochdi, Mohamed ^a   Delort, Anne Marie ^a   Guyot, Jacques ^a   Sancelme, Martine ^a   Gibot, Sylvie ^a   Gourcy, Jean Gabriel ^a   Dauphin, Gérard ^a   Gumila, Catherine ^b   Vial, Henri ^b   Jeminet, Georges ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; ION; IONOPHORE; MONENSIN DERIVATIVE; POTASSIUM ION; PROTON; SODIUM 23; SODIUM ION;

ANTIMALARIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS CEREUS; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ERYTHROCYTE; FUNGUS; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN CELL; ION TRANSPORT; MINIMUM INHIBITORY CONCENTRATION; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE; PLASMODIUM FALCIPARUM; POTASSIUM TRANSPORT; POTENTIOMETRY; PROTON TRANSPORT; SODIUM TRANSPORT;

ADULT; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTIMALARIALS; CANDIDA ALBICANS; ERYTHROCYTES; GRAM-POSITIVE BACTERIA; HUMANS; HYDROGEN; HYDROGEN-ION CONCENTRATION; ION TRANSPORT; IONOPHORES; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MONENSIN; PLASMODIUM FALCIPARUM; POTASSIUM; POTENTIOMETRY; SODIUM ISOTOPES; STEREOISOMERISM;

EID: 0030026789     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9505829     Document Type: Article

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