Potential role of transforming growth factor-β1 in terminating the immune response in patients with Guillain-Barré syndrome

Journal of Neurology

Volumn 243, Issue 3, 1996, Pages 264-268

  Sindern, Eckhart ^a   Schweppe, Klaus ^a   Ossege, Ludgera M ^a   Malin, Jean Pierre ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Enzyme linked immunosorbent assay; Guillain Barr syndrome; Transforming growth factor 1

Indexed keywords

CYTOKINE; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GUILLAIN BARRE SYNDROME; HUMAN; IMMUNE RESPONSE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANTIBODY FORMATION; CASE-CONTROL STUDIES; HUMANS; IMMUNE TOLERANCE; POLYRADICULONEUROPATHY; SOLUBILITY; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030025989     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00868524     Document Type: Article

References (19)

1. Asbury AK, Cornblath DR (1990) Assessment of current diagnostic criteria for Guillain-Barré syndrome. Ann Neurol 27: 21-24
2. Asbury AK, Arnason BGW, Adams RD (1969) The inflammatory lesion in idiopathic neuritis - its role in pathogenesis. Medicine 48: 173-215
3. Ayanlar Batuman O, Ferrero AP, Diaz A, Jiminez AS (1991) Regulation of transforming growth factor-β1 gene expression by glucocorticoids in normal human T lymphocytes. J Clin Invest 88: 1574-1580
4. Dennis PA, Rifkin DB (1991) Cellular activation of latent TGF-β requires binding to the cation independent mannose 6 phosphate/IGF type II receptor. Cell Biol 88: 580-584
5. Gamble JR, Vadas MA (1991) Endothelial cell adhesiveness for human T lymphocytes is inhibited by transforming growth factor-β. J Immunol 146: 1149-1154
6. Gregorian SK, Lee WP, Beck SL, Rostami A, Amento EP (1994) Regulation of experimental autoimmune neuritis by transforming growth factor-β1. Cell Immunol 156: 102-112
7. Hartung HP, Hughes RAC, Taylor WA, Heininger K, Reiners K, Toyka KV (1990) T cell activation in Guillain-Barré syndrome and MS: elevated serum levels of soluble IL-2 receptors. Neurology 40: 215-218
8. Hartung HP, Reiners K, Schmidt B, Stoll G, Toyka KV (1991) Serum interleukin-2 concentrations in Guillain-Barré syndrome and chronic idiopathic demyelinating polyradiculoneuropathy: comparison with other neurological diseases of presumed immunopathogenesis. Ann Neurol 30: 48-53
9. Hartung HP, Pollard JD, Harvey GK, Toyka KV (1995) Immunopathogenesis and treatment of the Guillain-Barré syndrome, part 1. Muscle Nerve 18: 137-153
10. Honovar M, Tharakan JKJ, Hughes RAC, Leihowitz S, Winer JB (1991) A clinicopathological study of the Guillain-Barré syndrome. Brain 114: 1245-1269
11. Jung S, Schluesener HJ, Schmidt B, Fontana A, Toyka KV, Hartung HP (1994) Therapeutic effect of transforming growth factor-β2 on actively induced EAN but not adoptive transfer EAN. Immunology 83: 545-551
12. Kiefer R, Gold J, Gehrmann J, Lindholm D, Wekerle H, Kreutzberg GW (1993) Transforming growth factor beta expression in reactive spinal cord microglia and meningeal inflammatory cells during experimental allergic neuritis. J Neurosci Res 36: 391-398
13. Koski CL, Gratz E, Sutherland J, Mayer RF (1986) Clinical correlation with antiperipheral nerve myelin antibodies in Guillain-Barré syndrome. Ann Neurol 19: 573-577
14. Ruegemer JJ, Ho SN, Augustine JA, et al (1990) Regulatory effects of transforming growth factor β on IL-2 and IL-4 dependent T cell cycle progression. J Immunol 144: 1767-1776
15. Shull MM, Ormsky I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D, Annunziata N, Doetschmann T (1992) Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 359: 693-699
16. Schluesener HJ, Lider O (1989) Transforming growth factor β1 and β2: cytokines with identical immunosuppressive effects and a potential role in the regulation of autoimmune T cell function. J Neuroimmunol 24: 249-258
17. Sharief MK, McLean B, Thompson EJ (1993) Elevated serum levels of tumor necrosis factor alpha in Guillain-Barré syndrome. Ann Neurol 33: 591-596
18. Winer JB, Hughes RAC, Osmond C (1988) A prospective study of acute idiopathic neuropathy. Clinical features and their prognostic value. J Neurol Neurosurg Psychiatry 51: 605-612
19. Zhu J, Mix E, Olsson T, Link H (1994) Cellular mRNA expression of interferon-gamma. IL-4 and transforming growth factor-beta (TGF-β) by rat mononuclear cells stimulated with peripheral nerve myelin antigens in experimental allergic neuritis. Clin Exp Immunol 98: 306-312