Alpha-2-adrenergic activation of proopiomelanocortin-containing neurons in the arcuate nucleus causes opioid-mediated hypotension and bradycardia

Neuroendocrinology

Volumn 63, Issue 3, 1996, Pages 275-283

  Li, Si Jia ^a   Scanlon, Martin N ^b   Járai, Zoltán ^a   Varga, Károly ^a   Gantenberg, Nicholas S ^b   Lazar Wesley, Eliane ^b   Kunos, George ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Beta endorphin; Blood pressure; Catecholamine receptors; Opiate peptides; Proopiomelancortin

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; BETA ENDORPHIN; CORBADRINE; HYDRALAZINE; METHYLDOPA; NALTREXONE; OPIATE RECEPTOR; PROOPIOMELANOCORTIN; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; DRUG INHIBITION; HYPOTENSION; HYPOTHALAMUS; IN SITU HYBRIDIZATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SOLITARY TRACT NUCLEUS;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; ARCUATE NUCLEUS; BETA-ENDORPHIN; BRADYCARDIA; HYPOTENSION; IN SITU HYBRIDIZATION; MALE; METHYLDOPA; MICROINJECTIONS; NEURONS; NORDEFRIN; PRO-OPIOMELANOCORTIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA; RNA, MESSENGER; YOHIMBINE;

EID: 0030025826     PISSN: 00283835     EISSN: 14230194     Source Type: Journal    
DOI: 10.1159/000126966     Document Type: Article

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