Particle-mediated nucleic acid immunization

Journal of Biotechnology

Volumn 44, Issue 1-3, 1996, Pages 37-42

  Haynes, Joel R ^a   McCabe, Dennis E ^a   Swain, William F ^a   Widera, Georg ^a   Fuller, James T ^a  

^a 8520 University Green   (United States)

Author keywords

DNA vaccine; Gene gun; HIV; Influenza; Nucleic acid vaccine; Pig; Rhesus monkey

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; CONTROLLED DRUG DELIVERY; DISEASES; DNA; GENES; LIVING SYSTEMS STUDIES; VACCINES;

CYTOTOXIC CELLULAR IMMUNE RESPONSES; GENE GUN; HUMORAL CELLULAR IMMUNE RESPONSES; INFLUENZA; PARTICLE MEDIATED NUCLEIC ACID IMMUNIZATION; RHESUS MONKEYS;

IMMUNIZATION;

DNA; DNA VACCINE; NUCLEIC ACID VACCINE; UNCLASSIFIED DRUG; VACCINE;

CONFERENCE PAPER; GENE TARGETING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; INFLUENZA; NONHUMAN; PLASMID; PREVENTION; PRIORITY JOURNAL; RHESUS MONKEY; SWINE; VACCINATION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; MACACA MULATTA; RODENTIA; SUS SCROFA;

EID: 0030025269     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-1656(96)80298-7     Document Type: Conference Paper

References (17)

1. Cheng, L., Ziegelhoffer, P.R. and Yang, N.-S. (1993) In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment. Proc. Natl. Acad. Sci. USA 90, 4455-4459.
2. Cox, G.J.M., Zamb, T.J. and Babiuk, L.A. (1993) Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA. J. Virol. 67, 5664-5667.
3. Eisenbraun, M.D., Fuller, D.H. and Haynes, J.R. (1993) Examination of parameters affecting the elicitation of humoral immune responses by particle bombardment-mediated genetic immunization. DNA and Cell Biol. 12, 791-797.
4. Davis, H.L., Michel, M.L. and Whalen, R.G. (1993) DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody. Hum. Mol. Genet. 2, 1847-1851.
5. Fuller, D.H. and Haynes, J.R. (1994) A qualitative progression in HIV-1 gp120-specific cytotoxic cellular and humoral immune responses in mice receiving a DNA-based gp120 vaccine. AIDS Res. and Hum. Retroviruses 10, 1433-1441.
6. Fynan, E.F., Webster, R.G., Fuller, D.H., Haynes, J.R., Santoro, J.C. and Robinson, H.L. (1993) DNA vaccines: protective immunizations by parenteral, mucosal and gene-gun inoculations. Proc. Natl. Acad. Sci. USA 90, 11478-11482.
7. Jiao, S., Williams, P., Berg, R.K., Hodgeman, B.A., Liu, L., Repetto, G. and Wolff, J.A. (1992) Direct gene transfer into nonhuman primate myofibers in vivo. Hum. Gene Ther. 3, 21-33.
8. McCabe, D. (1995) PCT patent application. Publication date by July 24, 1995.
9. Pertmer, T.M., Eisenbraun, M.D., McCabe, D., Prayaga, S.K., Fuller, D.H. and Haynes, J.R. (1995) Gene gun-based nucleic acid immunization: Elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA. Vaccine, in press.
10. Raz, E., Carson, D.A., Parker, S.E., Parr, T.B., Abai, A.M., Aichinger, G., Gromkowski, S.H., Singh, M., Lew, D., Yankauckas, M.A., Baird, S.M. and Rhodes, G.H. (1994) Intradermal gene immunization: The possible role of DNA uptake in the induction of cellular immunity to viruses. Proc. Natl. Acad. Sci. USA 91, 9519-9523.
11. Robinson, H.L., Hunt, L.A. and Webster, R.G. (1993) Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA. Vaccine 11, 957-960.
12. Sedegah, M., Hedstrom, R., Hobart, P. and Hoffman, S.L. (1994) Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein. Proc. Natl. Acad. Sci. USA 91, 9866-9870.
13. Tang, D.C., DeVit, M. and Johnston, S.A. (1992) Genetic immunization is a simple method for eliciting an immune response. Nature 356, 152-154.
14. Ulmer, J.B., Donnelly, J.J., Parker, S.E., Rhodes, G.H., Feigner, P.L., Dwarki, V.J., Gromkowski, S.H., Deck, R.R., DeWitt, C.M., Friedman, A., Hawe, L.A., Leander, K.R., Martinez, D., Perry, H.C., Shiver, J.W., Montgomery, D.L. and Liu, M.A. (1993) Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259, 1745-1749.
15. Wang, B., Ugen, K.E., Srikantan, V., Agadjanyan, M.G., Dang, K., Refaeli, Y., Sato, A.I., Boyer, J., Williams, W.V. and Weiner, D.B. (1993) Gene inoculation generates immune responses against human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 90, 4156-4160.
16. Wolff, J.A., Malone, R.W., Williams, P., Chong, W., Acsadi, G., Jani, A. and Felgner, P.L. (1990) Direct gene transfer into mouse muscle in vivo. Science 247, 1465-1468.
17. Wolff, J.A., Williams, P., Acsadi, G., Jiao, S., Jani, A. and Chong, W. (1991) Conditions affecting direct gene transfer into rodent muscle in vivo. BioTechniques 11, 474-485.