Glomerular Expression of Tissue Inhibitor of Metalloproteinase (TIMP-1) in Normal and Diabetic Rats

Journal of the American Society of Nephrology

Volumn 7, Issue 1, 1996, Pages 97-104

  Shankland, S J ^a,b   Ly, H ^a   Thai, K ^a   Scholey, J W ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Cortex; Diabetes; Glomerulus; TIMP 1

Indexed keywords

TISSUE INHIBITOR OF METALLOPROTEINASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; GLOMERULUS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

EID: 0030025254     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/asn.v7197     Document Type: Article

References (53)

1. Hirose K, Tsuchida H, Osterby R, Gundersen HJG: A strong correlation between glomerular filtration and filtration surface in diabetic hyperfunction. Lab Invest 1980;43:434-437.
2. Mauer SM, Steffes MW, Ellis EN, Sutherland DER, Brown DM, Goetz FC: Structural functional relationships in diabetic nephropathy. J Clin Invest 1984;74: 1143-1155.
3. Nerlich A, Schliecher E: Immunohistochemical localization of extracellular matrix components in human diabetic glomerular lesions. Am J Pathol 1991;139:889-899.
4. Striker LM, Killen PD, Chi E, Striker GE: The composition of glomerulosclerosis. I. Studies in focal sclerosis, crescentic glomerulosclerosis, and membranoproliferative glomerulonephritis. Lab Invest 1984;51:181-192.
5. Kreisberg JI, Ayo SH: The glomerular mesangium in diabetes mellitus. Kidney Int 1993;43:109-113.
6. Kashgarian M, Sterzl RB: The pathobiology of the mesangium. Kidney Int 1992;41:524-529.
7. Kreisberg JI: Hyperglycemia and microangiopathy: Direct regulation by glucose of microvascular cells. Lab Invest 1992;67:416-426.
8. Danne T, Spiro MJ, Spiro RG: Effect of high glucose on type IV collagen production by cultured glomerular epithelial, endothelial, and mesangial cells. Diabetes 1993; 42:170-177.
9. Ayo SH, Radnik RA, Garoni JA, Glass WF III, Kreisberg JI: High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells. Am J Pathol 1990;136:1339-1348.
10. Nakamura T, Miller D, Ruoslahti E, Border WA: Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-β1. Kidney Int 1992;41:1213-1221.
11. Cagliero E, Maiello M, Boeri D, Roy S, Lorenzi M: Increased expression of basement membrane component in human endothelial cells cultured in high glucose. J Clin Invest 1988;82:735-738.
12. Ziyadeh FN, Sharma K, Wolf G: Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor B. J Clin Invest 1994;93:536-542.
13. Studer RK, Craven PA, DeRubertis FR: Role for protein kinase C in the mediation of increased fibronectin accumulation by mesangial cells grown in high-glucose medium. Diabetes 1993;42:118-126.
14. Ayo SH, Radnik RA, Garoni JA, Glass III WF, Kreisberg JI: High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells. Am J Pathol 1990;136:1339-1348.
15. Haneda MR, Kikkawa R, Horide N, et al.: Glucose enhances type IV collagen production in cultured rat glomerular mesangial cells. Diabetologia 1991;34:198-200.
16. Nahman NS, Leonhart KL, Cosio FG, Hebert CL: Effects of high glucose on cellular proliferation and fibronectin production by cultured human mesangial cells. Kidney Int 1992;41:369-402.
17. Fukui M, Nakamura T, Ebihara I, Shirato I, Tomino Y, Koide H: ECM gene expression and its modulation by insulin in diabetic rats. Diabetes 1992;41:1520-1527.
18. Ihm C, Lee GSL, Nast CC, et al.: Early increased renal procollagen alpla1(iv) mRNA levels in streptozotocin induced diabetes. Kidney Int 1992;41:768-777.
19. Yamamoto T, Nakamura T, Noble NA, Ruoslahti E, Border WA: Expression of transforming growth factor β is elevated in human and experimental diabetic nephropathy. Proc Natl Acad Sci USA 1993;90:1814-1818.
20. McLennan SV, Fisher EJ, Yue DK, Turtle JR: High glucose concentration causes a decrease in mesangium degradation: A factor in the pathogenesis of diabetic nephropathy. Diabetes 1994;43:1041-1045.
21. Reckelhoff JF, Tygart VL, Mitias MM, Walcott JL: STZ-induced diabetes results in decreased activity of glomerular cathepsin and metalloprotease in rats. Diabetes 1993;42:1425-1432.
22. Davies M, Thomas GJ, Martin J, Lovett DH: The purification and characterisation of a glomerular basement membrane degrading neutral proteinase from the rat mesangial cells. Biochem J 1988;251:419-425.
23. Marten JM, Davies M, Thomas JG, Lovett DH: Human mesangial cells secrete a GBM-degrading neutral proteinase and a specific inhibitor. Kidney Int 1989;36:790-801.
24. Tomosugi N, Okada Y, Wada T, Nagai Y, Yokoyama H, Kobayashi K: Production of metalloproteinase (MMP) and inhibitor of metalloproteinase (TIMP-1) by human mesangial cells and its regulation [Abstract]. J Am Soc Nephrol 1991;1:584A.
25. Kitamura M, Mitarai T, Nagasawa R, et al.: Tissue inhibitor of metalloproteinase is highly expressed in cultured mesangial cells exposed to high glucose [Abstract]. J Am Soc Nephrol 1991;1:584A.
26. Davies M, Martin J, Thomas GJ, Lovett DH: Proteinases and glomerular matrix turnover. Kidney Int 1992;41: 671-678.
27. Nakamura T, Fukui I, Ebihara I, Osada S, Tomino Y, Koide H: Abnormal gene expression of matrix metalloproteinases and their inhibitor in glomeruli from diabetic rats. Renal Physiol Biochem 1994;17:316-325.
28. Nakamura T, Takahashi T, Fukui M, et al.: Enalapril attenuates increased gene expression of extracellular matrix components in diabetic rats. J Am Soc Nephrol 1995;5:1492-1497.
29. Shankland SJ, Scholey JW: Expression of transforming growth factor β1 during diabetic renal hypertrophy. Kidney Int 1994;46:430-442.
30. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein dye binding. Anal Biochem 1976; 72:248-254.
31. Wood GS, Warnke R: Suppression of endogenous avidinbinding activity in tissues and its relevance to biotin-avidin detection systems. J Histochem Cytochem 1981; 29:1196-1204.
32. Shankland SJ, Ly H, Thai K, Scholey JW: Increased glomerular capillary pressure alters glomerular cytokine expression. Circ Res 1994;75:844-853.
33. Tang WW, Feng L, Xia Y, Wilson CB: Extracellular matrix accumulation in immune mediated tubulointerstitial injury. Kidney Int 1994;45:1077-1084.
34. Jones CL, Buch S, Post M, McCulloch L, Liu E, Eddy AA: Pathogenesis of interstitial fibrosis in chronic puromycin aminonucleoside nephrosis. Kidney Int 1991;40: 1020-1031.
35. Osterby R, Gundersen HJG: Glomerular size and structure in type I diabetes mellitus: Early abnormalities. Diabetologia 1975;11:225-229.
36. Seyer-Hansen K: Renal hypertrophy in experimental diabetes mellitus. Kidney Int 1993;23:643-646.
37. Artacho-Perula E, Roldan-Villalobos R, Salcedo-Leal I, Vaamonde-Lemos R: Stereological estimates of volume-weighted mean glomerular volume in streptozotocin-diabetic rats. Lab Invest 1993;68(1):56-67.
38. Zivadeh FN: The extracellular matrix in diabetic glomerulopathy. Am J Kidney Dis 1993;22:736-744.
39. Carome MA, Striker LJ, Peten EP, et al.: Human glomeruli express TIMP-1 mRNA and TIMP-2 protein and mRNA. Am J Physiol 1993;264:F923-F929
40. Jones CL, Buch S, Post M, McCulloch L, Liu E, Eddy AA: Renal extracellular matrix accumulation in acute puromycin aminonucleoside nephrosis in the rat. Am J Pathol 1992;141:1381-1396.
41. Eddy A: Protein restriction reduces transforming growth factor-β and interstitial fibrosis in nephrotic syndrome. Am J Physiol 1994;266:F884-F893.
42. De Clerck YA: Purification and characterisation of a collagenase inhibitor produced by bovine vascular smooth muscle cells. Arch Biochem Biophys 1988;265: 98-37
43. De Clerck YA, Yean T, Ratzkin BJ, Lu HS, Langley KE: Purification and characterisation of two related but distinct metalloproteinase inhibitors secreted by bovine aortic endothelial cells. J Biol Chem 1989;264:17445-17453.
44. Steffes MW, Brown D, Basgen J: Amelioration of mesangial volume and surface alterations following islet transplantation in diabetic rats. Diabetes 1980;29:509-515.
45. The Diabetes Control and Complications Trial Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977-986.
46. Schaefer L, Schaefer RM, Ling H, Teschner M, Heidland A: Renal proteinases and kidney hypertrophy in experimental diabetes. Diabetologia 1994;37:567-571.
47. Overall CM, Wrana JL, Sodek J: Independent regulation of collagenase, 72-kDa progelatinase, and metalloproteinase inhibitor expression in human fibroblasts by transforming growth factor B. J Biol Chem 1989;264: 1860-1869.
48. Edwards DR, Murphy G, Reynolds JJ, et al.: Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J 1987; 6:1899-1904.
49. Zivedah FN, Chen Y, Davile A, Goldfarb S: Self limited stimulation of mesangial cell growth in high glucose: Autocrine activation of TGF β reduces; proliferation but increases mesangial matrix. Kidney Int 1992;42:647-656.
50. Kaname S, Uchida S, Ogato E, Kurokawa K: Autocrine secretion of transforming growth factor-β in cultured rat mesangial cells. Kidney Int 1992;42:1319-1327.
51. Nakamura T, Fukui M, Ebihara I, Osada, Nagaoka I, Tomino Y, Koide H: mRNA Expression of growth factors in glomeruli from diabetic rats. Diabetes 1993;42:450-456.
52. Border WA, Ruoslahti E: Transforming growth factor-β in disease: The dark side of tissue repair. J Clin Invest 1992;90:1-7
53. Song R, Singh AK, Alavi N, Leehey DJ: Decreased collagenase activity of mesangial cells incubated in high glucose media is reversed by neutralizing antibody to TGF-β1 [Abstract]. J Am Soc Nephrol 1994;5:972A.