Thrombin activity on dissected and anastomosed human arteries

Journal of Surgical Research

Volumn 60, Issue 1, 1996, Pages 193-198

  Johnson, P C ^a   Heil, B V ^a   Parva, B ^a   Hong, C ^a   Labadie, K ^a   Brezniak, D V ^b   Fenton II, J W ^b   Garrett, K ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b NEW YORK STATE DEPARTMENT OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESULFATOHIRUDIN; FIBRINOPEPTIDE A; HEPARIN; LEPIRUDIN; THROMBIN; THROMBIN INHIBITOR;

ARTERY ANASTOMOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMATOLOGICAL PARAMETERS; HUMAN; HUMAN TISSUE; PARTIAL THROMBOPLASTIN TIME; PLACENTA CIRCULATION; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; THROMBOGENESIS; THROMBOSIS;

EID: 0030025227     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1996.0031     Document Type: Article

References (37)

1. Johnson, P. C., and Barker, J. H. Thrombosis and antithrombotic therapy in microvascular surgery. Clin. Plastic Surg. 19: 799, 1992.
2. Acland, R. D., Anderson, G., Siemionow, M., and McCabe, S. Direct in vivo observations of embolic events in the microcirculation distal to a small-vessel anastomosis. Plastic Reconstr. Surg. 84: 280, 1989.
3. Wieslander, J. B., Dougan, P., Stjernquist, U., Aberg, M., and Bergentz, S. E. The influence of dextran and saline solution upon platelet behavior after microarterial anastomosis. Surg. Gynecol. Obstet. 163: 256, 1986.
4. Rosenbaum, T. J., and Sundt, T. M. Thrombus formation and endothelial alterations in microarterial anastomoses. J. Neurosurg. 47: 430, 1977.
5. Osgood, C. P., Dujovny, M., Faille, R., Barrionuevo, P. J., Longa, E. Z., and Matta, R. Early scanning electron microscopic evaluation of microvascular maneuvers. Angiology 27: 96, 1976.
6. Johnson, P. C. Platelet-mediated thrombosis in microvascular surgery: New knowledge and strategies. Plastic Reconstr. Surg. 86: 359, 1990.
7. Acland, R. Thrombus formation in microvascular surgery: An experimental study of the effects of surgical trauma. Surgery 73: 766, 1973.
8. Khouri, R. K., Cooley, B. C., Kenna, D. M., and Edstrom, L. E. Thrombosis of microvascular anastomoses in traumatized vessels: Fibrin versus platelets. Plastic Reconstr. Surg. 86: 110, 1990.
9. Dryjski, M., Olsson, P., and Swedenborg, J. Thrombin activity appearing on the vessel wall after trauma. Thromb. Haemostasis 54: 773, 1975.
10. Klement, P., Borm, A., Hirsh, J., Maraganore, J., Wilson, G., and Weitz, J. The effect of thrombin inhibitors on tissue plasminogen activator induced thrombolysis in a rat model. Thromb. Haemostasis 68: 64, 1992.
11. Hatton, M. W. C., and Moar, S. L. Comparison of the effects of heparin and hirudin on thrombin binding to the normal and the de-endothelialized rabbit aorta in vitro. Thromb. Haemostasis 66: 208, 1991.
12. Lam, J. Y. T., Chesebro, J. H., Steele, P. M., Heras, M., Webster, M. W. I., Badimon, L., and Fuster, V. Antithrombotic therapy for deep arterial injury by angioplasty: Efficacy of common platelet inhibition compared with thrombin inhibition in pigs. Circulation 84: 814, 1991.
13. Weitz, J. I., Hudoba, M., Massel, D., Maraganore, J., and Hirsh, J. Clot-bound thrombin is protected from inhibition by heparinantithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors. J. Clin. Invest. 86: 385, 1990.
14. Heras, M., Chesebro, J. H., Penny, W. J., Bailey, K. R., Lam, J. Y. T., Holmes, D. R., Reeder, G. S., Badimon, L., and Fuster, V. Importance of adequate heparin dosage in arterial angioplasty in a porcine model. Circulation 78: 654, 1990.
15. Heras, M., Chesebro, J. H., Penny, W. J., Bailey, K. R., Badimon, L., and Fuster, V. Effects of thrombin inhibition on the development of acute platelet-thrombus deposition during angioplasty in pigs. Circulation 79: 657, 1990.
16. Chesebro, J. H., Zoldhelyi, P., and Fuster, V. Pathogenesis of thrombosis in unstable angina. Am. J. Cardiol. 68: 2B, 1991.
17. Greenberg, B. M., Masem, M., and May, J. W. Therapeutic value of intravenous heparin in microvascular surgery: An experimental vascular thrombosis study. Plastic Reconstr. Surg. 82: 463, 1988.
18. May, J. W., and Rothkopf, D. M. Salvage of a failing microvascular free muscle flap by direct continuous intravascular infusion of heparin: A case report. Plastic Reconstr. Surg. 83:1045, 1989.
19. Zinberg, E. M., Choo, D. I., and Zotter, L. A. Effect of heparinized irrigating solutions on patency of experimental microvascular anastomoses. Microsurgery 10: 103, 1989.
20. Acland, R. D., Lubbers, L. L., Grafton, R. B., and Bensimon, R. Irrigating solutions for small blood vessel surgery-A histologic comparison. Plastic Reconstr. Surg. 5: 460, 1980.
21. Greenberg, B. M., Masem, M., Wangh, Y.-X., Rubin, P., and May, J. W. Efficacy of intraarterial heparin in maintaining microvascular patency: An experimental model. Plastic Reconstr. Surg. 87: 933, 1991.
22. Bentz, M. L., Sheppeck, R. A., Macpherson, T., Garrett, K. O., Billiar, T., Dickson, C. S., Janosky, J., and Johnson, P. C. Vasospasm and platelet deposition in human arteries: Effects of topical methylene blue. Plastic Reconstr. Surg. 88: 851, 1991.
23. Johnson, P. C., Sheppeck, R. A., Macpherson, T., Garrett, K. O., Janosky, J., and Bentz, M. L. Initial platelet deposition at the human micro vascular anastomosis: Effect on downstream platelet deposition to intact and injured vessels. Plastic Reconstr. Surg. 90: 650, 1992.
24. Higgins, D. L., Lewis, S. D., and Shafer, J. A. Steady state kinetic parameters for the conversion of human fibrinogen to fibrin. J. Biol. Chem. 258: 9276, 1993.
25. Weiss, H. J., Turitto, V. T., and Baumgartner, H. R. Effect of shear rate on platelet interaction with subendothelium in citrated and native bolld: Shear rate-dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier Syndrome. J. Lab. Clin. Med. 92: 750, 1978.
26. Adams, P. C., Fuster, V., Badimon, L., Badimon, J. J., and Chesebro, J. H. Platelet\vessel wall interactions, rheologic factors and thrombogenic substrate in acute coronary syndromes: Preventive strategies. Am. J. Cardiol. 60: 9G, 1987.
27. Araki, H., Muramoto, J., Nishi, K., Jougasaki, M., and Inoue, M. Heparin adheres to the damaged arterial wall and inhibits its thrombogenicity. Circ. Res. 71: 577, 1992.
28. Wagner, W. R., Johnson, P. C., Heil, B. V., Thompson, K. A., Kormos, R. L., and Griffith, B. P. Thrombin activity resides on LVAD Dacron inflow and outflow grafts. ASAIO J. 38: M634, 1992.
29. Rapold, H. J. Promotion of thrombin activity by thrombolytic therapy without simultaneous anticoagulation. Lancet 235: 481, 1990.
30. Sobel, B. E., and Hirsh, J. Principles and practice of coronary thrombolysis and conjunctive treatment. Am. J. Cardiol. 68: 382, 1991.
31. Voytik, S., Badylak, S. F., Burke, S., Klabunde, R. E., Henkin, J., and Simmons, A. The protective effect of heparin in a dog model of rethrombosis following pharmacologic thrombolysis. Thromb. Haemostasis 64: 438, 1990.
32. Eisenberg, P. R. Role of new anticoagulants as adjunctive therapy during thrombolysis. Am. J. Cardiol. 67: 19A, 1991.
33. Fenton, J. W., II. Thrombin interactions with hirudin. Thromb. Haemostasis 15: 265, 1989.
34. Marki, W. E., and Wallis, R. B. The anticoagulant and anti-thrombotic properties of hirudins. Thromb. Haemostasis 64: 344, 1990.
35. Talbot, M. D., Ambler, J., Butler, K D., Lees, C. M., Mitchessk, K. A., Robin, P. F., Tweed, M. F., and Wallis, R. B. The effects of recombinant desulphatohirudin on arterial thrombosis in rats. Haemostasis 21: 73, 1991.
36. Walenga, J. M., Pifarre, R., Hoppensteadt, D. A., and Fareed, J. Development of recombinant hirudin as a therapeutic anticoagulant and antithrombotic agent: Some objective considerations. Semin. Thromb. Haemostasis 15: 316, 1989.
37. Gast, A., Tschopp, T. B., and Baumgartner, H. R. Thrombin plays a key role in late platelet thrombus growth and/or stability. Effect of a specific thrombin inhibitor on thrombogenesis induced by aortic subendothelium exposed to flowing rabbit blood. Arteriosclerosis Thromb. 14: 1466, 1994.