Prouroguanylin and proguanylin: Purification from colon, structure, and modulation of bioactivity by proteases

Endocrinology

Volumn 137, Issue 1, 1996, Pages 257-265

  Hamra, F Kent ^a,b   Fan, Xiaohui ^a,b   Krause, William J ^b   Freeman, Ronald H ^b   Chin, David T ^b   Smith, Christine E ^c   Currie, Mark G ^c   Forte, Leonard R ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b University of Missouri   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

ANIMAL TISSUE; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME REGULATION; FLUID BALANCE; INTESTINE MUCOSA; NONHUMAN; OPOSSUM; PRIORITY JOURNAL; PROTEIN ISOLATION; SODIUM BALANCE; TISSUE DISTRIBUTION;

EID: 0030025049     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.1.8536621     Document Type: Article

References (35)

1. Currie MG, Fok KF, Kato J, Moore RJ, Hamra FK, Duffin KL, Smith CE 1992 Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci USA 89:947-951
2. Hamra FK, Forte LR, Eber SL, Pidhorodeckyj NV, Krause WJ, Freeman RH, Chin DT, Tompkins JA, Fok KF, Smith CE, Duffin KL, Siegel NR, Currie M G 1993 Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase. Proc Natl Acad Sci USA 90:10464-10468
3. Kita T, Smith CE, Fok KF, Duffin KL, Moore WM, Karabatsos PJ, Kachur JF, Hamra FK, Pidhorodeckyj NV, Forte LR, Currie M G 1994 Characterization of human uroguanylin: a member of the guanylin peptide family. Am J Physiol 266:F342-F348
4. Hamra FK, Krause WJ, Eber SL, Freeman RH, Smith CE, Currie MG, Forte LR, Colonic mucosa of the opossum contains uroguanylin and guanylin peptides. Am J Physiol, in press
5. Fan X, Hamra FK, Eber SL, Smith CE, Currie MG, Freeman RH, Forte L R 1995 Purification and properties of uroguanylin from rat urine. FASEB J 9:A6 (Abstract)
6. Forte LR, Currie M G 1995 Guanylin: a peptide regulator of epithelial transport. FASEB J 9:643-650
7. Forte LR, Hamra F K, Guanylin and uroguanylin: intestinal peptide hormones that regulate epithelial transport. News Physiol Sci, in press
8. Schulz S, Green CK, Yuen PST, Garbers D L 1990 Guanylyl cyclase is a heat-stable enterotoxin receptor. Cell 63:941-948
9. Krause WJ, Cullingford GL, Freeman RH, Eber SL, Richardson KC, Fok KF, Currie MG, Forte L R 1994 Distribution of heat-stable enterotoxin/guanylin receptors in the intestinal tract of man and other mammals. J Anat 184:407-417
10. Schulz S, Chrisman TD, Garbers D L 1992 Cloning and expression of guanylin. J Biol Chem 267:16019-16021
11. Forte LR, Eber SL, Turner JT, Freeman RH, Fok KF, Currie M G 1993 Guanylin stimulation of Cl secretion in human intestinal T84 cells via cyclic guanosine monophosphate. J Clin Invest 91:2423-2428
12. Greenberg RN, Crytzer JS, Hill MJ, Hamra FK, Krause WJ, Forte LR 1995 Stimulation of secretion and cGMP by uroguanylin, guanylin, and E. coli enterotoxin (ST) in suckling mouse intestine. FASEB J 9:A677 (Abstract)
13. Fonteles MC, Greenberg RN, Currie MG, Forte L R 1995 Guanylin and uroguanylin are GC-C binding intestinal peptide hormones with natriuretic and kaliuretic activity. J Invest Med 43:395A (Abstract)
14. Wiegand RC, Kato J, Currie MG 1992 Rat guanylin cDNA: characterization of the precursor of an endogenous activator of intestinal guanylate cyclase. Biochem Biophys Res Commun 185:812-817
15. de Sauvage FJ, Keshav S, Kuang W-J, Gillett N, Henzel W, Goeddel D V 1992 Precursor structure, expression, and tissue distribution of human guanylin. Proc Natl Acad Sci USA 89:9089-9093
16. Wiegand RC, Kato J, Huang MD, Fok KF, Kachur JF, Currie M G 1992 Human guanylin: cDNA isolation, structure, and activity. FEBS Lett 311:150-154
17. Kato J, Wiegand RC, Currie M G 1993 Characterization of the structure of preproguanylin. In: Brown BL, Dobson PRM (eds) Advances in Second Messengers and Phosphoprotein Research, Raven Press, New York, vol 28:139-142
18. Lewis LG, Witte DP, Laney DW, Currie MG, Cohen M B 1993 Guanylin mRNA is expressed in villus enterocytes of the rat small intestine and superficial epithelia of the rat colon. Biochem Biophys Res Commun 196:553-560
19. Li Z, Goy M F 1993 Peptide-regulated guanylate cyclase pathways in rat colon: in situ localization of GCA, GC-C, and guanylin mRNA. Am J Physiol 265:G394-G402
20. Cohen MB, Witte DP, Hawkins JA, Currie MG 1995 Immunohistochemical localization of guanylin in the rat small and large intestine. Biochem Biophys Res Commun 209:803-808
21. Li Z, Taylor-Blake B, Light AR, Goy M F 1995 Immunohistochemical localization of guanylin, an endogenous ligand for C-type guanylate cyclase. Gastroenterology 108:A986 (Abstract)
22. Cetin Y, Kuhn M, Kulaksiz H, Adermann K, Bargsten G, Grube D, Forssmann W- G 1994 Enterochromaffin cells of the digestive system: cellular source of guanylin, a guanylate cyclase activating protein. Proc Natl Acad Sci USA 91:2935-2939
23. Hill O, Kuhn M, Zucht H-D, Cetin Y, Kulaksiz H, Adermann K, Klock G, Rechkemmer G, Forssmann W-G, Magert H-J 1995 Analysis of the human guanylin gene and the processing and cellular localization of the peptide. Proc Natl Acad Sci USA 92:2046-2050
24. Garcia KC, de Sauvage FJ, Struble M, Henzel W, Reilly D, Goeddel DV 1993 Processing and characterization of human proguanylin expressed in Escherichia coli. J Biol Chem 268:22397-22401
25. Daniel H, Neugebauer B, Kratz A, Rehner G 1985 Localization of acid microclimate along intestinal villi of rat jejunum. Am J Physiol 248:G293-G298
26. Bown RL, Gibson JA, Sladen GE, Hicks B, Dawson A M 1974 Effects of lactulose and other laxatives on ileal and colonic pH as measured by a radiotelemetry device. Gut 15:999-1004
27. Chu S, Montrose M H 1995 Extracellular pH regulation in microdomains of colonic crypts: effects of short chain fatty acids. Proc Natl Acad Sci USA 92:3303-3307
28. Houmard J, Drapeau G R 1972 Staphylococcal protease: a proteolytic enzyme specific for glutamoyl bonds. Proc Nat Acad Sci USA 69:3506-3509
29. Kuhn M, Raida M, Adermann K, Schulz-Knappe P, Gerzer R, Heim J-M, Forssmann W-G 1993 The circulating bioactive form of human guanylin is a high molecular weight peptide (10.3 kDa). FEBS Lett 318:205-209
30. Lund PK, Moats-Staats BM, Simmons JG, Hoyt E, D'Ercoles AJ, Martin F, Van Wyk J J 1985 Nucleotide sequence analysis of a cDNA encoding human ubiquitin reveals that ubiquitin is synthesized as a precursor. J Biol Chem 260:7609-7613
31. Kita T, Smith CE, Duffin KL, Fok KF, Currie M G 1995 Characterization of bioactive guanylin released from rat small intestine. FASEB J 9:A632 (Abstract)
32. Nakazato M, Yamaguchi H, Shiomi K, Date Y, Fujimoto S, Kangawa K, Matsuo H, Matsukura S. 1994 Identification of 10-kDa proguanylin as a major guanylin molecule in human intestine and plasma and its increase in renal insufficiency. Biochem Biophys Res Commun 205:1966-1975
33. Forte LR, Krause WJ, Freeman R H 1989 Escherichia coli enterotoxin receptors: localization in opossum kidney, intestine, and testis. Am J Physiol 257:F874-F881
34. Freeman RH, Forte LR, Hamra FK, Currie MG, Krause W J 1994 Uroguanylin: a potential natriuretic peptide produced by the intestine. FASEB J 8:A552 (Abstract)
35. Lima AAM, Monteiro HSA, Fonteles M C 1992 The effects of Escherichia coli heat- stable enterotoxin in renal sodium tubular transport. Pharmacol Toxicol 70:163-167