The role of adenosine in functional hyperaemia in the coronary circulation of anaesthetized dogs

Journal of Physiology

Volumn 490, Issue 3, 1996, Pages 793-803

  Karim, F ^a   Goonewardene, I P ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOG; FEMALE; HEART DENERVATION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE OXYGEN CONSUMPTION; HEART RATE; HYPEREMIA; MALE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030024962     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1996.sp021187     Document Type: Article

References (36)

1. ADAM, K. R., BOYLES, S. & SCHOFIELD, P. C. (1970). Cardioselective beta adreaoeeptor blockade and the coronary circulation. British Journal of Pharmacology 40, 534-536.
2. BACCHUS, A., ELY, S. W., KNABB, R., RUBIO, R. R. & BERNE, R. M. (1982). Adenosine and coronary blood flow in conscious dogs during normal physiologic stimuli. American Journal of Physiology 243, H628-633.
3. BACHE, J. J., DAI, X. Z., SCHWARTZ, J. S. & HOMANS, D. C. (1988). Role of adenosine in coronary vasodilation during exercise. Circulation Research 62, 846-853.
4. BALLARD, H. J., COTTERRELL, D. & KARIM, F. (1987). Appearance of adenosine in venous blood from the contracting gracilis muscle and its role in vasodilatation in the dog. Journal of Physiology 387, 401-413.
5. BUFFINGTON, C. W. & FEIGL, E. O. (1981). Adrenergic coronary vasoconstriction in the presence of coronary stenosis in the dog. Circulation Research 48, 416-423.
6. DEWITT, D. F., WANGLER, R. D., THOMPSON, C. I. & SPARKS, H. V. JR (1983). Phasic release of adenosine during steady state metabolic stimulation in the isolated guinea pig heart. Circulation Research 53, 636-643.
7. DOBSON, J. G., FESTON, R. A. & ROMANO, F. D. (1987). The antiadrenergic actions of adenosine in the heart. In Topics and Perspectives in Adenosine Research, ed. GERLACH, E. & BECKBR, B. F., pp. 357-366. Springer-Verlag, Berlin.
8. DOWNEY, H. F., MERRILL, G. F., YONEKURA, S., WATANABE, N. & JONES, C. E. (1988). Adenosine deaminase attenuates norepinephrine induced coronary functional hyperaemia. American Journal of Physiology 254, H417-424.
9. GEWIRTZ, H., OLSSON, R. A., BRAUTIGAN, D. L., BROWN, P. R. & MOST, A. S. (1986a). Adenosine's role in regulating basal coronary arteriolar tone. American Journal of Physiology 250, H1030-1036.
10. GEWIRTZ, H., OLSSON, R. A. & MOST, A. S. (1986b). Role of adenosine in mediating myocardial blood flow response to isoproterenol: observations in closed chest, sedated, domestic swine. Cardiovascular Research 20, 504-511.
11. GIDDAY, J. M., HILL, H. E., RUBIO, R. & BERNE, R. M. (1988). Estimates of left ventricular interstitial fluid adenosine during catecholamine stimulation. American Journal of Physiology 254, H207-216.
12. GOONEWARDENE, I. P. & KARIM, F. (1991). Attenuation of exercise vasodilatation by adenosine deaminase in anaesthetized dogs. Journal of Physiology 442, 65-79
13. HEADRICK, J. & WILLIS, R. J. (1988). Contribution of adenosine to changes in coronary flow in metabolically stimulated rat heart. Canadian Journal of Physiology and Pharmacology 66, 171-173.
14. KARIM, F. & AL-OBAIDI, M. (1993). Modification of carotid chemoreceptor-induced changes in renal haemodynamics and function by carotid baroreflex in dogs. Journal of Physiology 466, 599-610.
15. KARIM, F., BALLARD, H. J. & COTTERRELL, D. (1988). Changes in adenosine release and blood flow in the contracting dog gracilis muscle. Pflügers Archiv 412, 106-112.
16. KARIM, F., MAJID, D. S. A. & SUMMERILL, R. A. (1989). The sympathetic nerve in the mediation of renal response to localized stimulation of atrial receptors in anaesthetized dogs. Journal of Physiology 417, 63-78.
17. KARIM, F., SOFOLA, O. A., HAINSWORTH, R. & WOOD, L. M. (1980). Inotropic responses of the heart to stimulation of aortic chemoreceptors in dogs. Circulation Research 46, 77-83.
18. KNABB, R. M., ELY, S. W., BACCHUS, A. N., RUBIO, R. R. & BERNE, R. M. (1983). Consistent parallel relationships among myocardial oxygen consumption, coronary blood flow and pericardial infitsate adenosine concentration with various interventions and β-blockade in the dog. Circulation Research 53, 33-41.
19. KNABB, R. M., GIDDAY, J. M., ELY, S. W., RUBIO, R. R. & BERNE, R. M. (1984). Effects of dipyridamole on myocardial adenosine and active hvperaemia American Journal of Physiology 247. H804-810.
20. KROLL, K. & FEIGL, E. O. (1985). Adenosine is unimportant in controlling coronary blood flow in unstressed dog hearts. American Journal of Physiology 249, H1176-1187.
21. MCKENZIE, J. E., STEFFEN, R. P. & HADDY, F. J. (1982). Relationships between adenosine and coronary resistance in conscious exercising dogs. American Journal of Physiology 242, H24-29.
22. MCKENZIE, J. E., STEFFEN, R. P. & HADDY, F. J. (1987). Effect of theophylline on adenosine production in the canine myocardium. American Journal of Physiology 252, H204-210.
23. MANFREDI, J. P. & SPARKS, H. V. JR (1982). Adenosine's role in coronary vasodilation induced by atrial pacing and norepinephrine. American Journal of Physiology 243, H536-545.
24. MAETIN, S. E., LENHARD, S. D., SCHMARKEY, L. S., OFFENDER, S. & ODLE, B. M. (1993). Adenosine regulates coronary blood flow during increased work and decreased supply. American Journal of Physiology 264, H1438-1446.
25. MERRILL, G. F., DOWNEY, H. F., YONEKURA, S., WATENABE, X. & JONES, C. E. (1988). Adenosine deaminase attenuates canine coronary vasodilation during regional non ischaemic myocardial hypoxia. Cardiovascular Research 22, 345-350.
26. MILLER, W. L., BELARDINELLI, L., BACCHUS, A. L., FOLEY, D. H., RUBIO, R. R. & BERNE, R. M. (1979). Canine myocardial adenosine and lactate production, oxygen consumption and coronary blood flow during stellate ganglia stimulation. Circulation Research 45, 715-718.
27. MOHRMAN, D. E. & FEIGL, D. E. (1978). Competition between sympathetic vasoconstriction and metabolic vasodilation in the canine coronary circulation. Circulation Research 42, 79-86.
28. OLSSON, R. A. (1987). Intra-arterial adenosine deaminase: a tool for assessing physiologic functions of adenosine. In Topics and Perspectives in Adenosine Research, ed. GERLACH, E. & BECKER, B. F., pp. 438-444. Springer-Verlag, Berlin.
29. POI, Y. O., COTTERRELL, D. & KARIM, F. (1994). Electrical pacing of the denervated heart of anaesthetized dogs increases adenosine in coronary sinus blood. Journal of Physiology 481, 21 P.
30. RANDALL, J. R. & JONES, C. E. (1985). Adenosine antagonist aminophylline attenuates pacing induced coronary functional hyperaemia. American Journal of Physiology 248, H1-7.
31. RICHARDT, G., WAAS, W., KRANZHOFER, R., MAYER, E. & SCHOMIG, A. (1987). Adenosine inhibits the exocytotic release of endogenous noradrenaline in rat hearts. Circulation Research 61, 117-123.
32. SAITO, D., NIXON, D. G., VOMACKA, R. B. & OLSSON, R. A. (1980). Relationship of cardiac oxygen usage, adenosine content and coronary resistance in dogs. Circulation Research 47, 875-882.
33. SAITO, D., STEINHART, C. R., NIXON, D. G. & OLSSON, R. A. (1981). Intracoronary adenosine deaminase reduces canine myocardial reactive hyperaemia. Circulation Research 49, 1262-1267.
34. SCHRADER, J., BAUMANN, G. & GERLACH, E. (1977). Adenosine as inhibitor of myocardial effects of catecholamines. Pflügers Archiv 372, 29-35.
35. SCHWARTZ, P. J. & STONE, H. L. (1977). Tonic influence of the sympathetic nervous system on myocardial reactive hyperaemia and on coronary blood flow distribution in dogs. Circulation Research 41, 51-58.
36. YOUNG, M. A., KNIGHT, D. R. & VATNER, S. F. (1987). Autonomic control of large coronary arteries and resistance vessels. Progress in Cardiovascular Diseases 30, 211-234.