Effect of monoclonal anti-CD4 and anti-CD8 on skin allograft survival in mice treated with donor bone marrow cells

Transplantation

Volumn 61, Issue 1, 1996, Pages 104-110

  De Fazio, Sally R ^a   Masli, Sharmila ^a   Gozzo, James J ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE ANTIBODY; OKT 4; OKT 8;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOSUPPRESSIVE TREATMENT; INTRAPERITONEAL DRUG ADMINISTRATION; LYMPHOCYTE DEPLETION; LYMPHOCYTE SUBPOPULATION; MALE; MOUSE; NONHUMAN; PERIOPERATIVE PERIOD; PRIORITY JOURNAL; SKIN TRANSPLANTATION; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; ANTIGENS, CD8; BONE MARROW TRANSPLANTATION; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOTHERAPY, ADOPTIVE; MICE; SKIN TRANSPLANTATION; TRANSPLANTATION, HOMOLOGOUS;

EID: 0030024930     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199601150-00021     Document Type: Article

References (35)

1. Wood ML, Monaco AP, Gozzo JJ, Liegeois A. Use of homozygous allogeneic bone marrow for induction of tolerance with antilymphocyte serum: dose and timing. Transplant Proc 1971; 3: 676.
2. Hartner WC, De Fazio SR, Maki T, Markees TG, Monaco AP, Gozzo JJ. Prolongation of renal allograft survival in antilymphocyte-serum-treated dogs by postoperative injection of density-gradient-fractionated donor bone marrow. Transplantation 1986; 42: 593.
3. Thomas JM, Carver FM, Foil MB, et al. Renal allograft tolerance induced with ATG and donor bone marrow in outbred rhesus monkeys. Transplantation 1983; 36: 104.
4. Markees TG, De Fazio SR, Gozzo JJ. Prolongation of impure, murine islet allografts with antilymphoctye serum and donor-specific bone marrow. Transplantation 1992; 53: 521.
5. Bonnefoy-Bérard N, Vincent C, Revillard J-P. Antibodies against functional leukocyte surface molecules in polyclonal antilymphocyte and antithymocyte globulins. Transplantation 1991; 51: 669.
6. Rebellato LM, Gross U, Verbanac KM, Thomas JM. A comprehensive definition of the major antibody specificities in polyclonal rabbit antithymocyte globulin. Transplantation 1994; 57: 685.
7. Rebellato L, Gross U, Carver M, et al. Treatment of rhesus monkey allograft recipients with a combination of anti-T-cell monoclonal antibodies. Transplant Proc 1993; 25: 598.
8. Maki T, Gottschalk R, Wood ML, Monaco AP. Specific unresponsiveness to skin allografts in anti-lymphocyte serum-treated, marrow-injected mice: participation of donor-derived suppressor T cells. J Immunol 1981; 127: 1433.
9. Thomas JM, Verbanac KM, Thomas FT. The veto mechanism in transplant tolerance. Transplant Rev 1991; 5: 209.
10. Wood ML, Monaco AP. Suppressor cells in specific unresponsiveness to skin allografts in ALS-treated, marrow-injected mice. Transplantation 1980; 29: 196.
11. Maki T, Simpson M, Monaco AP. Development of suppressor T cells by antilymphocyte serum treatment in mice. Transplantation 1982; 34: 376.
12. Verbanac KM, Carver FM, Haisch CE, Thomas JM. A role for transforming growth factor-beta in the veto mechanism in transplant tolerance. Transplantation 1994; 57: 893.
13. De Fazio SR, Gozzo JJ. Splenic suppressor cells in allograft recipients treated with ALS and donor bone marrow cells. In: Alexander JW, Good R, eds. Transplantation tolerance. Austin, TX: RG Landes (in press).
14. Markees TM, De Fazio SR, Gozzo JJ. Prolongation of adult skin allograft survival by cotransplantation of neonatal skin in antilymphocyte serum and donor bone marrow cell-treated mice. Transplantation 1990; 50: 911.
15. Litchfield JT. A method for rapid graphic solution of time-percent effect curves. J Pharmacol Exp Ther 1949; 97: 399.
16. Gozzo JJ, Wood ML, Monaco A. Studies on ALS in mice. VIII. Effect of immunizing cell type and dose on immunosuppressive potency and content of irrelevant antibody. Transplantation 1972; 14: 358.
17. Shi Y, Bissonnette RP, Parfrey N, Szalay M, Kubo RT, Green DR. In vivo administration of monoclonal antibodies to the CDS T cell receptor complex induces cell death (apoptosis) in immature thymocytes. J Immunol 1991; 146: 3340.
18. Qin S, Wise M, Cobbold SP, Benjamin R, Waldmann H. Induction of classical transplantation tolerance in the adult. J Exp Med 1990; 169: 779.
19. Pearson TC, Bushell AK, Darby CR, West LJ, Morris PJ, Wood KJ. Lymphocyte changes associated with prolongation of cardiac allograft survival in adult mice using anti-CD4 monoclonal antibody. Clin Exp Immunol 1993; 92: 211.
20. De Fazio SR, Hartner WC, Monaco AP, Gozzo JJ. Effect of posttransplantation administration of peripheral blood lymphocytes in skin-grafted mice treated with antilymphocyte serum or antilymphocyte serum plus bone marrow. Transplantation 1987; 44: 70.
21. Wood ML, Monaco AP, Gottschalk R. Characterization of spleen cells capable of inducing unresponsiveness in ALS-treated mice. Transplantation 1991; 51: 208.
22. Monaco AP, Liegeois A, Wood ML, Clark AW. Active enhancement of tissue allografts with antilymphocyte serum and bone marrow. Adv Nephrol 1975; 5: 135.
23. Hartner WC, De Fazio SR, Markees TG, et al. Effect of cyclosporin A supplementation on renal allograft survival in ALS plus bone marrow treated dogs. Transplant Proc 1989; 21: 959.
24. Wakabayashi H, Cook DJ, Posner M, et al. Batch-to-batch variations in rabbit antithymocyte globulin preparations. Transplant Proc 1991; 23: 1125.
25. Isobe M, Yagita H, Okumura K, Ihara A. Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science 1992; 255: 1125.
26. Herbert J, Roser B. Strategies of monoclonal antibody therapy that induce permanent tolerance of organ transplants. Transplantation 1988; 46: 128S.
27. Shizuru JA, Seydel KB, Flavin TF, et al. Induction of donor-specific unresponsiveness to cardiac allografts in rats by pre-transplant anti-CD4 monoclonal antibody therapy. Transplantation 1990; 50: 366.
28. Kruisbeek AM. In vivo depletion of CD4- and CD8-specific T cells. In: Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, eds. Current protocols in immunology. New York: Wiley, 1991: 4.1.1
29. Hartner WC, Monaco AP, Gozzo JJ. Effect of timing of bone marrow injection on the prolongation of skin grafts in ALS-treated mice. Transplant Proc 1989; 21: 242.
30. Simpson M, Gozzo JJ. Studies on the mechanism of action of rabbit anti-mouse thymocyte serum I. Induction of suppressor cells. Transplantation 1980; 30: 64.
31. Mjörnstedt L, Olausson M, Lindholm L, Soderstrom T, Brynger H. Mechanisms maintaining transplantation tolerance in anti-thymocyte globulin-treated rats. Transplantation 1987; 44: 669.
32. + suppressor cell and its mechanism of action. J Exp Med 1990; 171: 141.
33. Qin S, Cobbold SP, Pope H, et al. "Infectious" transplantation tolerance. Science 1993; 259: 974.
34. Wood ML, Orosz CG, Gottschalk R, Monaco AP. The effect of injection of donor bone marrow on the frequency of donor-reactive CTL in antilymphocyte serum-treated, grafted mice. Transplantation 1992; 54: 665.
35. Jaques BC, Neison P, Bolton EM, et al. The mechanism of anti-CD4 induced T cell inhibition and early intracellular signalling events [Abstract 339]. Presented at the 15th International Congress of the Transplantation Society, Kyoto, Japan, 1994.