-
2
-
-
0002662404
-
Potential cellular and genetic mechanisms for insulin resistance in the common disorders of diabetes and obesity
-
D.E. Moller, editor. John Wiley and Sons, Chichester, England
-
Seely, B L , and J. Olefsky. 1993 Potential cellular and genetic mechanisms for insulin resistance in the common disorders of diabetes and obesity. In Insulin Resistance. D.E. Moller, editor. John Wiley and Sons, Chichester, England. 187-252
-
(1993)
Insulin Resistance
, pp. 187-252
-
-
Seely, B.L.1
Olefsky, J.2
-
3
-
-
0028918346
-
Insulin resistance and non-insulin-dependent diabetes mellitus: Cellular and molecular mechanisms
-
Olefsky, J.M., and J.J. Nolan. 1995. Insulin resistance and non-insulin-dependent diabetes mellitus: cellular and molecular mechanisms. Am. J. Clin. Nutr. 61:980S-986S.
-
(1995)
Am. J. Clin. Nutr.
, vol.61
-
-
Olefsky, J.M.1
Nolan, J.J.2
-
4
-
-
0028337353
-
High glucose condition activates protein tyrosine phosphatases and deactivates insulin receptor function in insulin-sensitive rat 1 fibroblasts
-
Ide, R., H. Maegawa, R. Kikkawa, Y. Shigeta, and A. Kashiwagi. 1994. High glucose condition activates protein tyrosine phosphatases and deactivates insulin receptor function in insulin-sensitive rat 1 fibroblasts. Biochem. Biophys. Res Commun. 201:71-77.
-
(1994)
Biochem. Biophys. Res Commun.
, vol.201
, pp. 71-77
-
-
Ide, R.1
Maegawa, H.2
Kikkawa, R.3
Shigeta, Y.4
Kashiwagi, A.5
-
5
-
-
0028031151
-
Glucose-induced translocation of protein kinase C isoforms in rat-1 fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase
-
Berti, L . L. Mosthaf, G. Kroder, M. Kellerer, S. Tippmer, J. Mushack, E. Setter, K Seedorf, and H Haring 1994. Glucose-induced translocation of protein kinase C isoforms in rat-1 fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase. J Biol. Chem. 269:3381-3386.
-
(1994)
J Biol. Chem.
, vol.269
, pp. 3381-3386
-
-
Berti, L.1
Mosthaf, L.2
Kroder, G.3
Kellerer, M.4
Tippmer, S.5
Mushack, J.6
Setter, E.7
Seedorf, K.8
Haring, H.9
-
6
-
-
0141434860
-
Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity
-
Bollag, G.E., R.A. Roth, J. Beaudoin, D. Mochly-Rosen, and D.E.J. Koshland 1986. Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. Proc. Natl Acad. Sci USA. 83:5822-5824.
-
(1986)
Proc. Natl Acad. Sci USA.
, vol.83
, pp. 5822-5824
-
-
Bollag, G.E.1
Roth, R.A.2
Beaudoin, J.3
Mochly-Rosen, D.4
Koshland, D.E.J.5
-
7
-
-
0023834876
-
Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity
-
Takayama, S., M.F. White, and C.R. Kahn. 1988. Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity. J Biol. Chem. 263.3440-3447.
-
(1988)
J Biol. Chem.
, vol.263
, pp. 3440-3447
-
-
Takayama, S.1
White, M.F.2
Kahn, C.R.3
-
8
-
-
0026015007
-
Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells
-
Muller, H.K., M. Kellerer, B. Ermel, A. Muhlhofer, B. Obermaier-Kusser, B. Vogt, and H.U Haring. 1991. Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells. Diabetes 40:1440-1448.
-
(1991)
Diabetes
, vol.40
, pp. 1440-1448
-
-
Muller, H.K.1
Kellerer, M.2
Ermel, B.3
Muhlhofer, A.4
Obermaier-Kusser, B.5
Vogt, B.6
Haring, H.U.7
-
9
-
-
0029035830
-
Effects of high glucose concentrations on human mesangial cell proliferation
-
Cosio, F.G. 1995. Effects of high glucose concentrations on human mesangial cell proliferation J. Am. Soc. Nephrol. 5:1600-1609.
-
(1995)
J. Am. Soc. Nephrol.
, vol.5
, pp. 1600-1609
-
-
Cosio, F.G.1
-
10
-
-
0028146675
-
Translocation of protein kinase C alpha and zeta in rat glomerular mesangial cells cultured under high glucose conditions
-
Kikkawa, R., M Haneda, T. Uzu, D. Koya, T. Sugimoto, and Y Shigeta. 1994. Translocation of protein kinase C alpha and zeta in rat glomerular mesangial cells cultured under high glucose conditions. Diabetologia 37:838-841.
-
(1994)
Diabetologia
, vol.37
, pp. 838-841
-
-
Kikkawa, R.1
Haneda, M.2
Uzu, T.3
Koya, D.4
Sugimoto, T.5
Shigeta, Y.6
-
11
-
-
0027977387
-
Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues
-
Inoguchi, T., P. Xia, M. Kunisaki, S Higashi. E.P. Feener, and G.L. King. 1994, Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues. Am. J. Physiol 267:E369-E379.
-
(1994)
Am. J. Physiol
, vol.267
-
-
Inoguchi, T.1
Xia, P.2
Kunisaki, M.3
Higashi, S.4
Feener, E.P.5
King, G.L.6
-
12
-
-
0025054967
-
Threonine 1336 of the human insulin receptor is a major target for phosphorylation by protein kinase C
-
Lewis, R.E., L. Cao, D. Perregaux, and M.P. Czech. 1990. Threonine 1336 of the human insulin receptor is a major target for phosphorylation by protein kinase C. Biochemistry 29.1807-1813.
-
(1990)
Biochemistry
, vol.29
, pp. 1807-1813
-
-
Lewis, R.E.1
Cao, L.2
Perregaux, D.3
Czech, M.P.4
-
13
-
-
0025870736
-
Multisite serine phosphorylation of the insulin and IGF-I receptors in transfected cells
-
Pillay, T.S., J. Whittaker, R. Lammers, A. Ullrich, and K. Siddle. 1991. Multisite serine phosphorylation of the insulin and IGF-I receptors in transfected cells. FEBS Lett 288:206-211.
-
(1991)
FEBS Lett
, vol.288
, pp. 206-211
-
-
Pillay, T.S.1
Whittaker, J.2
Lammers, R.3
Ullrich, A.4
Siddle, K.5
-
14
-
-
0028150886
-
Site-specific anti-phosphopeptide antibodies, use in assessing insulin receptor serine/threonine phosphorylation state and identification of serine-1327 as a novel site of phorbol ester-induced phosphorylation
-
Coghlan, M.P., T S. Pillay, J.M Tavare, and K. Siddle. 1994. Site-specific anti-phosphopeptide antibodies, use in assessing insulin receptor serine/threonine phosphorylation state and identification of serine-1327 as a novel site of phorbol ester-induced phosphorylation. Biochem J. 303:893-899.
-
(1994)
Biochem J.
, vol.303
, pp. 893-899
-
-
Coghlan, M.P.1
Pillay, T.S.2
Tavare, J.M.3
Siddle, K.4
-
15
-
-
0027964572
-
Characterization of phorbol ester-stimulated serine phosphorylation of the human insulin receptor
-
Feener, E.P , T. Shiba, K.Q. Hu, P.A Wilden, M.F. White, and G.L. King. 1994 Characterization of phorbol ester-stimulated serine phosphorylation of the human insulin receptor. Biochem. J 303:43-50.
-
(1994)
Biochem. J
, vol.303
, pp. 43-50
-
-
Feener, E.P.1
Shiba, T.2
Hu, K.Q.3
Wilden, P.A.4
White, M.F.5
King, G.L.6
-
16
-
-
0027945494
-
Phorbol ester stimulates phosphorylation on serine 1327 of the human insulin receptor
-
Lewis, R.E., D.J Volle, and S.D. Sanderson. 1994 Phorbol ester stimulates phosphorylation on serine 1327 of the human insulin receptor. J. Biol. Chem. 269:26259-26266.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26259-26266
-
-
Lewis, R.E.1
Volle, D.J.2
Sanderson, S.D.3
-
17
-
-
85035158033
-
Mechanisms of glucose-induced inhibition of insulin action
-
Pillay, T.S., S. Xiao, and J M. Olefsky. 1995. Mechanisms of glucose-induced inhibition of insulin action. J. Invest. Med. 43(Suppl 1):90A
-
(1995)
J. Invest. Med.
, vol.43
, Issue.1 SUPPL.
-
-
Pillay, T.S.1
Xiao, S.2
Olefsky, J.M.3
-
18
-
-
4243191743
-
Mechanism of glucose-induced inhibition of insulin receptor phosphorylation and kinase activity
-
Pillay, T S. 1994. Mechanism of glucose-induced inhibition of insulin receptor phosphorylation and kinase activity. Diabetes. 43(Suppl. 1):240A.
-
(1994)
Diabetes.
, vol.43
, Issue.1 SUPPL.
-
-
Pillay, T.S.1
-
19
-
-
0024358334
-
Augmented mitogenesis and impaired metabolic signaling mediated by a truncated insulin receptor
-
Thies, R.S., A. Ullrich, and D.A McClain. 1989. Augmented mitogenesis and impaired metabolic signaling mediated by a truncated insulin receptor. J. Biol Chem. 264:12820-12825.
-
(1989)
J. Biol Chem.
, vol.264
, pp. 12820-12825
-
-
Thies, R.S.1
Ullrich, A.2
McClain, D.A.3
-
20
-
-
0023905461
-
Properties of a human insulin receptor with a COOH-terminal truncation. I. Insulin binding, autophosphorylation, and endocytosis
-
McClain, D.A., H. Maegawa, J. Levy, T. Huecksteadt, T.J. Dull, J Lee, A. Ullrich, and J.M. Olefsky. 1988. Properties of a human insulin receptor with a COOH-terminal truncation. I. Insulin binding, autophosphorylation, and endocytosis. J. Biol Chem. 263:8904-8911.
-
(1988)
J. Biol Chem.
, vol.263
, pp. 8904-8911
-
-
McClain, D.A.1
Maegawa, H.2
Levy, J.3
Huecksteadt, T.4
Dull, T.J.5
Lee, J.6
Ullrich, A.7
Olefsky, J.M.8
-
21
-
-
0023907193
-
Properties of a human insulin receptor with a COOH-terminal truncation. II. Truncated receptors have normal kinase activity but are defective in signaling metabolic effects
-
Maegawa, H., D.A. McClain, G. Freidenberg, J.M Olefsky, M. Napier, T. Lipari, T.J. Dull, J. Lee, and A. Ullrich. 1988. Properties of a human insulin receptor with a COOH-terminal truncation. II. Truncated receptors have normal kinase activity but are defective in signaling metabolic effects. J. Biol. Chem. 263:8912-8917.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 8912-8917
-
-
Maegawa, H.1
McClain, D.A.2
Freidenberg, G.3
Olefsky, J.M.4
Napier, M.5
Lipari, T.6
Dull, T.J.7
Lee, J.8
Ullrich, A.9
-
22
-
-
0028837993
-
Insulin stimulates the tyrosine dephosphorylation of pp125 focal adhesion kinase
-
Pillay, T.S., T Sasaoka, and J.M Olefsky. 1995. Insulin stimulates the tyrosine dephosphorylation of pp125 focal adhesion kinase. J. Biol. Chem. 270: 991-994.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 991-994
-
-
Pillay, T.S.1
Sasaoka, T.2
Olefsky, J.M.3
-
23
-
-
0026686231
-
Enhancement of insulin- And EGF-stimulated tyrosine phosphorylation of endogenous substrates by sodium selenate
-
Pillay, T.S., and M.W. Makgoba. 1995 Enhancement of insulin- and EGF-stimulated tyrosine phosphorylation of endogenous substrates by sodium selenate. FEBS Lett. 308:38-42.
-
(1995)
FEBS Lett.
, vol.308
, pp. 38-42
-
-
Pillay, T.S.1
Makgoba, M.W.2
-
24
-
-
0029034774
-
Inhibition of Map kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor
-
Pang, L., S. Sawada, S.J. Decker, and A.R. Saltiel. 1995. Inhibition of Map kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J Biol. Chem 270:13585-13588.
-
(1995)
J Biol. Chem
, vol.270
, pp. 13585-13588
-
-
Pang, L.1
Sawada, S.2
Decker, S.J.3
Saltiel, A.R.4
-
25
-
-
0025942516
-
The bis-indolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C
-
Toullec, D., P. Pianetti, H. Coste, P. Bellevergue, T. Grand-Perret, M. Ajakane, V. Baudet, P. Boissin, E. Boursier, and F. Loriolle. 1991. The bis-indolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol. Chem. 266.15771-15781.
-
(1991)
J Biol. Chem.
, vol.266
, pp. 15771-15781
-
-
Toullec, D.1
Pianetti, P.2
Coste, H.3
Bellevergue, P.4
Grand-Perret, T.5
Ajakane, M.6
Baudet, V.7
Boissin, P.8
Boursier, E.9
Loriolle, F.10
-
26
-
-
0027248964
-
Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C
-
Wilkinson, S.E., P.J. Parker, and J S. Nixon. 1993 Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem. J. 294:335-337.
-
(1993)
Biochem. J.
, vol.294
, pp. 335-337
-
-
Wilkinson, S.E.1
Parker, P.J.2
Nixon, J.S.3
-
27
-
-
0025105970
-
Purification and characterization of bovine brain type I phosphatidylinositol kinase
-
Morgan, S.J., A.D. Smith, and P.J Parker. 1990. Purification and characterization of bovine brain type I phosphatidylinositol kinase. Eur. J. Biochem. 191:761-767.
-
(1990)
Eur. J. Biochem.
, vol.191
, pp. 761-767
-
-
Morgan, S.J.1
Smith, A.D.2
Parker, P.J.3
-
28
-
-
0027954632
-
Activation of protein kinase C alpha inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor substrate-1
-
Chin, I.E., F. Liu, and R.A. Roth 1994 Activation of protein kinase C alpha inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor substrate-1. Mol Endocrinol. 8:51-58.
-
(1994)
Mol Endocrinol.
, vol.8
, pp. 51-58
-
-
Chin, I.E.1
Liu, F.2
Roth, R.A.3
-
29
-
-
0028227166
-
Biochemical mechanisms of insulin resistance
-
Roth, R.A., F. Liu, and J.E. Chin. 1994. Biochemical mechanisms of insulin resistance. Horm. Res. 41(Suppl. 2):51-55.
-
(1994)
Horm. Res.
, vol.41
, Issue.2 SUPPL.
, pp. 51-55
-
-
Roth, R.A.1
Liu, F.2
Chin, J.E.3
-
30
-
-
0027418067
-
Overexpression of protein kinase C isoenzymes alpha, beta I, gamma, and epsilon in cells overexpressing the insulin receptor. Effects on receptor phosphorylation and signaling
-
Chin, J E , M. Dickens, J.M. Tavare, and R.A. Roth. 1993. Overexpression of protein kinase C isoenzymes alpha, beta I, gamma, and epsilon in cells overexpressing the insulin receptor. Effects on receptor phosphorylation and signaling. J. Biol. Chem. 268:6338-6347.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 6338-6347
-
-
Chin, J.E.1
Dickens, M.2
Tavare, J.M.3
Roth, R.A.4
-
31
-
-
0025945689
-
Insulin-stimulated serine/threonine phosphorylation of the insulin receptor: Paucity of threomne 1348 phosphorylation in vitro indicates the involvement of more than one serine/threonine kinase in vivo
-
Pillay, T.S., and K. Siddle. 1991. Insulin-stimulated serine/threonine phosphorylation of the insulin receptor: paucity of threomne 1348 phosphorylation in vitro indicates the involvement of more than one serine/threonine kinase in vivo. Biochem. Biophys Res Commun. 179:962-971.
-
(1991)
Biochem. Biophys Res Commun.
, vol.179
, pp. 962-971
-
-
Pillay, T.S.1
Siddle, K.2
-
32
-
-
0029195142
-
The MAP kinase cascade
-
Campbell, J.S., R. Seger, J.D. Graves, L.M. Graves, A.M. Jensen, and E.G. Krebs. 1995. The MAP kinase cascade. Recent Prog. Horm. Res. 50:131-159
-
(1995)
Recent Prog. Horm. Res.
, vol.50
, pp. 131-159
-
-
Campbell, J.S.1
Seger, R.2
Graves, J.D.3
Graves, L.M.4
Jensen, A.M.5
Krebs, E.G.6
-
33
-
-
0028008323
-
Deciphering the MAP kinase pathway
-
L'Allemain, G. 1994. Deciphering the MAP kinase pathway. Prog Growth Factor Res. 5:291-334.
-
(1994)
Prog Growth Factor Res.
, vol.5
, pp. 291-334
-
-
L'Allemain, G.1
-
34
-
-
0029117994
-
The protein kinase C isoforms leading to MAP-kinase activation in CHO cells
-
Yamaguchi, K., K. Ogita, S. Nakamura, and Y. Nishizuka. 1995. The protein kinase C isoforms leading to MAP-kinase activation in CHO cells. Biochem. Biophys. Res. Commun. 210:639-647.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.210
, pp. 639-647
-
-
Yamaguchi, K.1
Ogita, K.2
Nakamura, S.3
Nishizuka, Y.4
-
35
-
-
0027408363
-
Interaction of the human insulin receptor tyrosine kinase from the baculovirus expression system with protein kinase C in a cell-free system
-
Ahn, J., D.B. Donner, and O.M. Rosen. 1993. Interaction of the human insulin receptor tyrosine kinase from the baculovirus expression system with protein kinase C in a cell-free system. J. Biol. Chem. 268:7571-7576.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 7571-7576
-
-
Ahn, J.1
Donner, D.B.2
Rosen, O.M.3
-
36
-
-
0021985413
-
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
-
Ullrich, A., J.R. Bell, E.Y Chen, R. Herrera, L.M. Petruzzelli, T J. Dull, A Gray, L. Coussens, Y.C. Liao, and M. Tsubokawa. 1985. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature (Lond.). 313.756-761.
-
(1985)
Nature (Lond.)
, vol.313
, pp. 756-761
-
-
Ullrich, A.1
Bell, J.R.2
Chen, E.Y.3
Herrera, R.4
Petruzzelli, L.M.5
Dull, T.J.6
Gray, A.7
Coussens, L.8
Liao, Y.C.9
Tsubokawa, M.10
-
37
-
-
0029010308
-
The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif
-
Songyang, Z., B. Margolis, M. Chaudri, S.E. Shoelson, and L.C. Cantley. 1995. The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif. J. Biol. Chem. 270.14863-14866.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14863-14866
-
-
Songyang, Z.1
Margolis, B.2
Chaudri, M.3
Shoelson, S.E.4
Cantley, L.C.5
-
38
-
-
0027969225
-
Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system
-
O'Neill, T.J., A. Craparo, and T.A. Gustafson. 1994. Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system. Mol. Cell Biol. 14:6433-6442.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 6433-6442
-
-
O'Neill, T.J.1
Craparo, A.2
Gustafson, T.A.3
-
39
-
-
0028912999
-
Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain
-
Gustafson, T.A., W He, A. Craparo, C.D. Schaub, and T.J O'Neill. 1995. Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain. Mol. Cell Biol 15:2500-2508.
-
(1995)
Mol. Cell Biol
, vol.15
, pp. 2500-2508
-
-
Gustafson, T.A.1
He, W.2
Craparo, A.3
Schaub, C.D.4
O'Neill, T.J.5
-
41
-
-
0028887716
-
C-terminus or juxtamembrane deletions in the insulin receptor do not affect the glucose-dependent inhibition of the tyrosine kinase activity
-
Mosthaf, L., L. Berti, M. Kellerer, J. Mushack, E. Seffer, B. Bossenmaier, M. Coghlan, K. Siddle, A. Ullrich, and H.U. Haring. 1995. C-terminus or juxtamembrane deletions in the insulin receptor do not affect the glucose-dependent inhibition of the tyrosine kinase activity. Eur. J. Biochem 227:787-791.
-
(1995)
Eur. J. Biochem
, vol.227
, pp. 787-791
-
-
Mosthaf, L.1
Berti, L.2
Kellerer, M.3
Mushack, J.4
Seffer, E.5
Bossenmaier, B.6
Coghlan, M.7
Siddle, K.8
Ullrich, A.9
Haring, H.U.10
-
42
-
-
0029111429
-
Mechanism of insulin receptor kinase inhibition in non-insulin-dependent diabetes mellitus patients. Phosphorylation of serine 1327 or threonine 1348 is unaltered
-
Kellerer, M., M. Coghlan, E. Capp, A. Muhlhofer, G. Kroder, L. Mosthaf, P. Galante, K. Siddle, and H.U. Haring. 1995. Mechanism of insulin receptor kinase inhibition in non-insulin-dependent diabetes mellitus patients. Phosphorylation of serine 1327 or threonine 1348 is unaltered. J. Clin Invest. 96:6-11.
-
(1995)
J. Clin Invest.
, vol.96
, pp. 6-11
-
-
Kellerer, M.1
Coghlan, M.2
Capp, E.3
Muhlhofer, A.4
Kroder, G.5
Mosthaf, L.6
Galante, P.7
Siddle, K.8
Haring, H.U.9
-
43
-
-
0028274267
-
Identification of serines-967/968 in the juxtamembrane region of the insulin receptor as insulin stimulated phosphorylation sites
-
Liu, F., and R A. Roth. 1994. Identification of serines-967/968 in the juxtamembrane region of the insulin receptor as insulin stimulated phosphorylation sites. Biochem. J. 298:471-477
-
(1994)
Biochem. J.
, vol.298
, pp. 471-477
-
-
Liu, F.1
Roth, R.A.2
-
44
-
-
0028141653
-
Identification of serines-1035/1037 in the kinase domain of the insulin receptor as protein kinase C alpha mediated phosphorylation sites
-
Liu, F., and R.A. Roth. 1994. Identification of serines-1035/1037 in the kinase domain of the insulin receptor as protein kinase C alpha mediated phosphorylation sites. FEBS Lett. 352:389-392.
-
(1994)
FEBS Lett.
, vol.352
, pp. 389-392
-
-
Liu, F.1
Roth, R.A.2
-
45
-
-
0025880943
-
Insulin-stimulated serine and threonine phosphorylation of the human insulin receptor. An assessment of the role of serines 1305/1306 and threonine 1348 by their replacement with neutral or negatively charged amino acids
-
Tavare, J.M , B. Zhang, L. Ellis, and R A. Roth. 1991 Insulin-stimulated serine and threonine phosphorylation of the human insulin receptor. An assessment of the role of serines 1305/1306 and threonine 1348 by their replacement with neutral or negatively charged amino acids. J. Biol. Chem. 266:21804-21809.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 21804-21809
-
-
Tavare, J.M.1
Zhang, B.2
Ellis, L.3
Roth, R.A.4
-
46
-
-
0022800838
-
Insulin-like growth factor I receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity
-
Ullrich, A., A. Gray, A.W. Tam, T. Yang-Feng, M. Tsubokawa, C. Collins, W. Henzel, T. Le Bon, S Kathuria, and E. Chen. 1986. Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO (Eur. Mol. Biol. Organ.) J. 5:2503-2512.
-
(1986)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.5
, pp. 2503-2512
-
-
Ullrich, A.1
Gray, A.2
Tam, A.W.3
Yang-Feng, T.4
Tsubokawa, M.5
Collins, C.6
Henzel, W.7
Le Bon, T.8
Kathuria, S.9
Chen, E.10
-
47
-
-
0021924895
-
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
-
Ebina, Y., L. Ellis, K. Jarnagin, M. Edery, L. Graf, E. Clauser, J.H. Ou, F. Masiarz, Y.W. Kan, and I.D. Goldfine. 1985. The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling. Cell. 40:747-758.
-
(1985)
Cell
, vol.40
, pp. 747-758
-
-
Ebina, Y.1
Ellis, L.2
Jarnagin, K.3
Edery, M.4
Graf, L.5
Clauser, E.6
Ou, J.H.7
Masiarz, F.8
Kan, Y.W.9
Goldfine, I.D.10
-
48
-
-
0028492597
-
Protein kinase C - An enzyme and its relatives
-
Stabnel, S. 1994. Protein kinase C - an enzyme and its relatives. Semin. Cancer Biol. 5:277-284.
-
(1994)
Semin. Cancer Biol.
, vol.5
, pp. 277-284
-
-
Stabnel, S.1
-
49
-
-
0029060391
-
Protein kinase C and lipid signaling for sustained cellular responses
-
Nishizuka, Y. 1995. Protein kinase C and lipid signaling for sustained cellular responses. FASEB (Fed. Am. Soc. Exp. Biol.) J. 9:484-496.
-
(1995)
FASEB (Fed. Am. Soc. Exp. Biol.) J.
, vol.9
, pp. 484-496
-
-
Nishizuka, Y.1
-
50
-
-
0038856677
-
Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- And antibody-stimulated glucose uptake and receptor kinase activity
-
Ebina, Y., E. Araki, M Taira, F. Shimada, M. Mori, C.S. Craik, K. Siddle, S.B Pierce, R.A. Roth, and W.J. Rutter. 1987. Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity. Proc. Natl. Acad Sci. USA. 84:704-708.
-
(1987)
Proc. Natl. Acad Sci. USA
, vol.84
, pp. 704-708
-
-
Ebina, Y.1
Araki, E.2
Taira, M.3
Shimada, F.4
Mori, M.5
Craik, C.S.6
Siddle, K.7
Pierce, S.B.8
Roth, R.A.9
Rutter, W.J.10
-
51
-
-
0024205862
-
Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation
-
Maegawa, H., J.M. Olefsky, S. Thies, D Boyd, A. Ullrich, and D.A. McClain. 1988. Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation J. Biol. Chem. 263: 12629-12637.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 12629-12637
-
-
Maegawa, H.1
Olefsky, J.M.2
Thies, S.3
Boyd, D.4
Ullrich, A.5
McClain, D.A.6
-
52
-
-
0023028208
-
Tumor-promoting phorbol esters increase the Km of the ATP-binding site of the insulin receptor kinase from rat adipocytes
-
Haring, H., D. Kirsch, B. Obermaier, B. Ermel, and F. Machicao 1986. Tumor-promoting phorbol esters increase the Km of the ATP-binding site of the insulin receptor kinase from rat adipocytes. J. Biol. Chem. 261:3869-3875.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 3869-3875
-
-
Haring, H.1
Kirsch, D.2
Obermaier, B.3
Ermel, B.4
Machicao, F.5
-
53
-
-
0025157186
-
Insulin-sensitive phosphorylation of serine 1293/1294 on the human insulin receptor by a tightly associated serine kinase
-
Lewis, R.E , G.P. Wu, R.G. MacDonald, and M.P. Czech. 1990. Insulin-sensitive phosphorylation of serine 1293/1294 on the human insulin receptor by a tightly associated serine kinase. J. Biol. Chem. 265:947-954.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 947-954
-
-
Lewis, R.E.1
Wu, G.P.2
MacDonald, R.G.3
Czech, M.P.4
|