Guanine, pyrazolo[3,4-d]pyrimidine, and triazolo[4,5-d]pyrimidine (8-azaguanine) phosphonate acyclic derivatives as inhibitors of purine nucleoside phosphorylase

Journal of Medicinal Chemistry

Volumn 39, Issue 4, 1996, Pages 949-956

  Beauchamp, Lilia M ^a,b   Tuttle, Joel V ^a,c   Rodriguez, Martha E ^a,b   Sznaidman, Marcos L ^a,b  

^a Burroughs Wellcome Co   (United States)

^b Division of Organic Chemistry

^c Division of Experimental Therapy

Author keywords

[No Author keywords available]

Indexed keywords

8 AZAGUANINE; 8 AZAPURINE DERIVATIVE; ACICLOVIR DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR; PYRAZOLO[3,4 B]PYRIDINE DERIVATIVE;

ARTICLE; BINDING SITE; ENZYME ACTIVE SITE; ENZYME INHIBITION; ERYTHROCYTE MEMBRANE; GRAFT REJECTION; NONHUMAN; PSORIASIS; PURINE METABOLISM; REACTION ANALYSIS; RHEUMATOID ARTHRITIS; STRUCTURE ANALYSIS; T CELL LEUKEMIA;

EID: 0030024396     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950736k     Document Type: Article

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