A highly amplified mouse gene is homologous to the human interferon-responsive Sp100 gene encoding an autoantigen associated with nuclear dots

Molecular and Cellular Biology

Volumn 16, Issue 3, 1996, Pages 1150-1156

  Grötzinger, Thilo ^a   Jensen, Kirsten ^a   Guldner, Hans H ^a   Sternsdorf, Thomas ^a   Szostecki, Carin ^a   Schwab, Manfred ^b   Savelyeva, Larissa ^b   Reich, Berthold ^a   Will, Hans ^a,c  

^a UNIVERSITY OF HAMBURG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; INTERFERON;

ANIMAL CELL; ARTICLE; CHROMOSOME 1; GENE AMPLIFICATION; GENE LOCATION; GENE LOCUS; GENE MAPPING; GENETIC CODE; GENETIC ORGANIZATION; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE HOMOLOGY;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, NUCLEAR; AUTOANTIGENS; BASE SEQUENCE; CHROMOSOME BANDING; CHROMOSOME MAPPING; CLONING, MOLECULAR; GENE AMPLIFICATION; HUMANS; INTERFERONS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NUCLEAR PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA;

EID: 0030024111     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.3.1150     Document Type: Article

References (42)

1. Agulnik, S., C. Plass, W. Traut, and H. Winking. 1993 Evolution of a long-range repeat family in chromosome 1 of the genus Mus Mamm. Genome 4:704-710.
2. Alitalo, K., M. Schwab, C. C. Lin, H. E. Varmus, and J. M. Bishop. 1983. Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. Proc. Natl. Acad. Sci. USA 80:1707-1711.
3. Auffray, C., and F. Rougeon. 1980. Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma rumor RNA. Eur. J. Biochem. 107:303-314.
4. Barker, P. E., and M. Schwab. 1993. Junction mapping of translocation chromosomes by fluorescence at situ hybridization and computer image analysis in human solid tumors. Methods Mol. Genet. 2:129-154.
5. Barnes, W. M. 1994. PCR amplification of up to 35-kb DNA with high fidelity and high yield from λ bacteriophage templates. Proc. Natl. Acad. Sci. USA 91:2216-2220.
6. Biedler, J. L., and B. A. Spengler. 1976. Metaphase chromosome anomaly: association with drug resistance and cell-specific products. Science 191:185-187.
7. Dayhoff, M. O., R. M. Schwartz, and B. C. Orcutt. 1978. A model of evolutionary change in proteins, p. 345-352. In M. O. Dayhoff (ed.), Atlas of protein sequence and structure, vol. 5, suppl. 3. National Biomedical Research Foundation, Washington, D.C.
8. de Bruijn, M. H. L., A. M. van der Bliek, J. L. Biedler, and P. Borst. 1986. Differential amplification and disproportionate expression of five genes in three multidrug-resistant Chinese hamster lung cell lines. Mol. Cell. Biol. 6:4717-4722.
9. Deppert, W., M. Haug, and T. Steinmayer. 1987. Modulation of p53 protein expression during cellular transformation with simian virus 40. Mol Cell. Biol. 7:4453-4463.
10. Dyck, J. A., G. G. Maul, W. H. Miller, Jr., J. D. Chen, A. Kakizuka, and R. M. Evans. 1994. A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein. Cell 76:333-343.
11. Eckert, W. A., C. Plass, A. Weith, W. Traut, and H. Winking. 1991. Transcripts from amplified sequences of an inherited homogeneously staining region in chromosome 1 of the house mouse (Mus musculus). Mol. Cell. Biol. 11:2229-2235.
12. Grötzinger, T., K. Jensen, and H. Will. Unpublished data.
13. Guldner, H. H., C. Szostecki, T. Grötzinger, and H. Will. 1992. IFN enhance expression of Sp100, an autoantigen in primary biliary cirrhosis. J. Immunol. 149:4067-4073.
14. Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
15. Koken, M. H. M., G. Linares-Cruz, F. Quignon, A. Viron, M. K. Chelbi-Alix, J. Sobczak-Thépot, L. Juhlin, L. Degos, F. Calvo, and H. de Thé. 1995. The PML growth-suppressor has an altered expression in human oncogenesis. Oncogene 10:1315-1324.
16. Koken, M. H. M., F. Puvion-Dutilleul, M. C. Guillemin, A. Viron, G. Linares-Cruz, N. Stuurman, L. de Jong, C. Szostecki, F. Calvo, C. Chomienne, L. Degos, E. Puvion, and H. de Thé. 1994. The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion. EMBO J. 13:1073-1083.
17. Korioth, F., C. Gieffers, G. G. Maul, and J. Frey. 1995. Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment. J. Cell Biol 130:1-13.
18. Levy, D. E., D. S. Kessler, R. Pine, N. Reich, and J. E. Darnell, Jr. 1988. Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev. 2:383-393.
19. Liu, J.-H., Z.-M. Mu, and K.-S. Chang. 1995. PML suppresses oncogenic transformation of NIH/3T3 cells by activated neu. J. Exp. Med. 181:1965-1973.
20. Looney, J. E., C. Ma, T.-H. Leu, W. F. Flintoff, W. B. Troutman, and J. L. Hamlin. 1988. The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure. Mol. Cell. Biol. 8:5268-5279.
21. Maul, G. G., H. H. Guldner, and J. G. Spivack. 1993 Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0). J. Gen. Virol. 74:2679-2690
22. Mu, Z.-M., K.-V. Chin, J.-H. Liu, G. Lozano, and K.-S. Chang. 1994. PML a growth suppressor disrupted in acute promyelocytic leukemia. Mol Cell. Biol. 14:6858-6867.
23. O'Brien, S. J., J. E. Womack, L. A. Lyons, K. J. Moore, N. A. Jenkins, and N. G. Copeland. 1993. Anchored reference loci for comparative genome mapping in mammals. Nat. Genet. 3:103-112.
24. Purmann, L., C. Plass, M. Grüneberg, H. Winking, and W. Traut. 1992. A long-range repeat cluster in chromosome 1 of the house mouse, Mus musculus, and its relation to a germline homogeneously staining region. Genomics 12:80-88
25. Puvion-Dutilleul, F., M. K. Chelbi-Alix, M. Koken, F. Quignon, E. Puvion. and H. de Thé. 1995. Adenovirus infection induces rearrangements in the intranuclear distribution of the nuclear body-associated PML protein. Exp Cell Res. 218:9-16.
26. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. 2nd ed Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N Y.
27. Schwab, M., K. Alitalo, H. E. Varmus, J. M. Bishop, and D. George. 1983. A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenoeortical tumour cells. Nature (London) 303:497-501.
28. Sternsdorf, T., H. H. Guldner, C. Szostecki, T. Grotzinger, and H. Will. 1995 Two nuclear dot-associated proteins, PML and Sp100, are often co-autoimmunogenic in patients with primary biliary cirrhosis. Scand. J. Immunol. 42:257-268.
29. Szostecki, C. 1992. Ph.D. thesis. Ludwig-Maximilians-Universität, Munich, Germany.
30. Szostecki, C., H. H. Guldner, H. J. Netter, and H. Will. 1990. Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis. J. Immunol. 145:4338-4347.
31. Szostecki, C., H. Krippner, E. Penner, and F. A. Bautz. 1987. Autoimmune sera recognize a 100 kD nuclear protein antigen (Sp100). Clin. Exp. Immunol. 68:108-116.
32. Szostecki, C., and H. Will. Unpublished data.
33. Szostecki, C., H. Will, H. J. Netter, and H. H. Guldner. 1992. Autoantibodies to the nuclear Sp100 protein in primary biliary cirrhosis and associated diseases: epitope specificity and immunoglobulin class distribution. Scand. J. Immunol. 36:555-564.
34. Tan, E. M. 1989. Antinuclear antibodies, diagnostic markers for autoimmune diseases and probes for cell biology. Adv. Immunol. 44:93-151.
35. Terris, B., V. Baldin, S. Dubois, C Degott, J.-F. Flejou, D. Hénin, and A. Dejean. 1995. PML nuclear bodies are general targets for inflammation and cell proliferation. Cancer Res. 55:1590-1597.
36. Traut, W., M. F. Seldin, and H. Winking. 1992. Genetic mapping and assignment of a long-range repeat cluster to band D of chromosome 1 in Mus musculus and M. spretus. Cytogenet. Cell Genet. 60:128-130.
37. Traut, W., H. Winking, and S. Adolph. 1984. An extra segment in chromosome 1 of wild Mus musculus: a C-band positive homogeneously staining region. Cytogenet. Cell Genet. 38:290-297.
38. Tso, J. Y., X.-H. Sun, T.-H. Kao, K. S. Reece, and R. Wu. 1985. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene Nucleic Acids Res. 13:2485-2502.
39. Weichenhan, D., B. Kunze, C. Plass, T. Hellwig, H. Winking, and W. Traut. 1995. A transcript family from a long-range repeat cluster of the house mouse. Genome 38:239-245
40. Weis, K., S. Rambaud, C. Lavau, J. Jansen, T. Carvalho, M. Carmo-Fonseca, A. Lamond, and A. Dejean. 1994. Retinoic acid regulates aberrant nuclear localization of PML-RARa in acute promyelocytic leukemia cells. Cell 76: 345-356
41. Winking, H., A. Weith, B. Boldyreff, K. Moriwaki, K. Fredga, and W. Traut. 1991. Polymorphic HSRs in chromosome 1 of the two semispecies Mus musculus musculus and M. m. domesticus have a common origin in an ancestral population. Chromosoma 100:147-151.
42. Xie, K., E. J. Lambie, and M. Snyder. 1993. Nuclear dot antigens may specify transcriptional domains in the nucleus. Mol. Cell. Biol. 13:6170-6179.