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Volumn 77, Issue 5, 1996, Pages 893-899

Phase II trial of recombinant human interleukin-2 and interferon-alpha-2a: Implications for the treatment of patients with metastatic melanoma

Author keywords

Chemotherapy; Clinical trial; Cytokine; Human; Interferon alpha; Interleukin 2; Metastatic melanoma

Indexed keywords

INTERLEUKIN 2; RECOMBINANT ALPHA2A INTERFERON;

EID: 0030024048     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19960301)77:5<893::AID-CNCR13>3.0.CO;2-Z     Document Type: Article
Times cited : (20)

References (21)
  • 2
    • 0025988834 scopus 로고
    • Studies of interferons in the therapy of melanoma
    • Kirkwood JM. Studies of interferons in the therapy of melanoma. Semin Oncol 1991; 18(5 Suppl 7):83-90.
    • (1991) Semin Oncol , vol.18 , Issue.5 SUPPL. 7 , pp. 83-90
    • Kirkwood, J.M.1
  • 3
    • 0023619262 scopus 로고
    • In Vivo anti-tumor activity of combinations of interferon alpha and interleukin-2 in a murine model. Correlation of efficacy with the induction of cytotoxic cells resembling natural killer cells
    • Brunda MJ, Bellantoni D, Sulich V. In Vivo anti-tumor activity of combinations of interferon alpha and interleukin-2 in a murine model. Correlation of efficacy with the induction of cytotoxic cells resembling natural killer cells. Int J Cancer 1987:40:365-71.
    • (1987) Int J Cancer , vol.40 , pp. 365-371
    • Brunda, M.J.1    Bellantoni, D.2    Sulich, V.3
  • 4
    • 0023836117 scopus 로고
    • In Vivo anti-tumor activity of multiple injections of recombinant combinations of interleukin-2 alone and in combination with three different types of recombinant interferon, on various synergeneic murine tumors
    • Iigo M, Sakurai M, Tamura T, Saijo N, Hoshi A. In Vivo anti-tumor activity of multiple injections of recombinant combinations of interleukin-2 alone and in combination with three different types of recombinant interferon, on various synergeneic murine tumors. Cancer Res 1988;48:260-4.
    • (1988) Cancer Res , vol.48 , pp. 260-264
    • Iigo, M.1    Sakurai, M.2    Tamura, T.3    Saijo, N.4    Hoshi, A.5
  • 5
    • 0023680153 scopus 로고
    • Synergistic antitumor effects of combination immunotherapy with recombinant interleukin-2 and recombinant hybrid α-interferon in the treatment of established murine hepatic metastases
    • Cameron RB, McIntosh JK, Rosenberg SA. Synergistic antitumor effects of combination immunotherapy with recombinant interleukin-2 and recombinant hybrid α-interferon in the treatment of established murine hepatic metastases. Cancer Res 1988; 48:5810-17.
    • (1988) Cancer Res , vol.48 , pp. 5810-5817
    • Cameron, R.B.1    McIntosh, J.K.2    Rosenberg, S.A.3
  • 6
    • 0024433613 scopus 로고
    • Concomitant administration of recombinant human interleukin-2 and recombinant interferon a-2A in cancer patients: A phase 1 study
    • Lee KH, Talpaz M, Rothberg JM, Murray JL, Papadopoulos N, Plager C, et al. Concomitant administration of recombinant human interleukin-2 and recombinant interferon a-2A in cancer patients: A phase 1 study. J Clin Oncol 1989:7:1726-32.
    • (1989) J Clin Oncol , vol.7 , pp. 1726-1732
    • Lee, K.H.1    Talpaz, M.2    Rothberg, J.M.3    Murray, J.L.4    Papadopoulos, N.5    Plager, C.6
  • 10
    • 0027524697 scopus 로고
    • Randomized phase III trial of treatment with high-dose interleukin-2 either alone or in combination with interferon alpha-2a in patients with advanced melanoma
    • Sparano JA, Fisher RI, Sunderland M, Margolin K, Ernest ML. Sznol M, et al. Randomized phase III trial of treatment with high-dose interleukin-2 either alone or in combination with interferon alpha-2a in patients with advanced melanoma. J Clin Oncol 1993; 10:1969-77.
    • (1993) J Clin Oncol , vol.10 , pp. 1969-1977
    • Sparano, J.A.1    Fisher, R.I.2    Sunderland, M.3    Margolin, K.4    Ernest, M.L.5    Sznol, M.6
  • 11
    • 0022527746 scopus 로고
    • Immunotherapy of murine sarcomas using lymphokine activated killer (LAK) cells: Optimization of the schedule and route of administration of recombinant interleukin-2
    • Ettinghausen SE, Rosenberg SA. Immunotherapy of murine sarcomas using lymphokine activated killer (LAK) cells: Optimization of the schedule and route of administration of recombinant interleukin-2. Cancer Res 1986:46:2784-92.
    • (1986) Cancer Res , vol.46 , pp. 2784-2792
    • Ettinghausen, S.E.1    Rosenberg, S.A.2
  • 12
    • 0024849183 scopus 로고
    • Combination therapy with interleukin-2 and alpha-interferon for the treatment of patients with advanced cancer
    • Rosenberg SA, Lotze MT, Yang JC, Linehan WM, Seipp C, Calabro S, et al. Combination therapy with interleukin-2 and alpha-interferon for the treatment of patients with advanced cancer. J Clin Oncol 1989;7:1863-74.
    • (1989) J Clin Oncol , vol.7 , pp. 1863-1874
    • Rosenberg, S.A.1    Lotze, M.T.2    Yang, J.C.3    Linehan, W.M.4    Seipp, C.5    Calabro, S.6
  • 13
    • 0028106484 scopus 로고
    • Randomized comparison of high-dose and low-dose intravenous interleukin-2 for the therapy of metastatic renal cell carcinoma: An interim report
    • Yang JC, Topalian SL, Parkinson D, Schwartzentruber DJ, Weber JS, Ettinghausen SE, et al. Randomized comparison of high-dose and low-dose intravenous interleukin-2 for the therapy of metastatic renal cell carcinoma: an interim report. J Clin Oncol 1994:12:1572-6.
    • (1994) J Clin Oncol , vol.12 , pp. 1572-1576
    • Yang, J.C.1    Topalian, S.L.2    Parkinson, D.3    Schwartzentruber, D.J.4    Weber, J.S.5    Ettinghausen, S.E.6
  • 14
    • 0027407531 scopus 로고
    • Interleukin-2 in cancer treatment: Disappointing or (still) promising? A review
    • Maas RA, Dullens HFJ, Den Otter W. Interleukin-2 in cancer treatment: disappointing or (still) promising? A review. Cancer Immunol Immunother 1993:36:141-8.
    • (1993) Cancer Immunol Immunother , vol.36 , pp. 141-148
    • Maas, R.A.1    Dullens, H.F.J.2    Den Otter, W.3
  • 17
    • 0028594033 scopus 로고
    • Combination of chemotherapy with Interleukin-2 and Interferon-Alpha for the treatment of advanced melanoma
    • Buzaid AC, Legha S. Combination of chemotherapy with Interleukin-2 and Interferon-Alpha for the treatment of advanced melanoma. Semin Oncol 1994:21:23-8.
    • (1994) Semin Oncol , vol.21 , pp. 23-28
    • Buzaid, A.C.1    Legha, S.2
  • 18
    • 0026734180 scopus 로고
    • Sequential chemoimmunotherapy in the treatment of metastatic melanoma
    • Richards JM, Mehta N, Ramming K, Skosey P. Sequential chemoimmunotherapy in the treatment of metastatic melanoma. J Clin Oncol 1992; 10:1338-43.
    • (1992) J Clin Oncol , vol.10 , pp. 1338-1343
    • Richards, J.M.1    Mehta, N.2    Ramming, K.3    Skosey, P.4
  • 19
    • 0027486041 scopus 로고
    • Sequential chemoimmunotherapy with cisplatin, interleukin-2, and interferon alpha-2a for metastatic melanoma
    • Khayar D, Borel C, Tourani JM, Benhammouda A, Antoine E, Rixe O, et al. Sequential chemoimmunotherapy with cisplatin, interleukin-2, and interferon alpha-2a for metastatic melanoma. J Clin Oncol 1993; 11:2173-80.
    • (1993) J Clin Oncol , vol.11 , pp. 2173-2180
    • Khayar, D.1    Borel, C.2    Tourani, J.M.3    Benhammouda, A.4    Antoine, E.5    Rixe, O.6
  • 20
    • 0343550981 scopus 로고
    • Durable complete responses in metastatic melanoma treated with biochemotherapy using Cisplatin + Vinblastine + DTIC (CVD) and IL-2 + Interferon-alpha
    • Abstr 1305
    • Legha SS, Ring S, Eton O, Plager C, Buzaid A, Papadopoulos N. Durable complete responses in metastatic melanoma treated with biochemotherapy using Cisplatin + Vinblastine + DTIC (CVD) and IL-2 + Interferon-alpha. Proc Am Soc Clin Oncol 1995; 14(Abstr 1305):412.
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 412
    • Legha, S.S.1    Ring, S.2    Eton, O.3    Plager, C.4    Buzaid, A.5    Papadopoulos, N.6
  • 21
    • 0026314720 scopus 로고
    • Therapeutic implications of tumor physiology
    • Jain RK. Therapeutic implications of tumor physiology. Curr Opin Oncol 1991;3:1105-08.
    • (1991) Curr Opin Oncol , vol.3 , pp. 1105-1108
    • Jain, R.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.