Localization of the DCTN1 gene encoding p150Glued to human chromosome 2p13 by Fluorescence in Situ hybridization

Genomics

Volumn 31, Issue 3, 1996, Pages 398-399

  Holzbaur, Erika L F ^a   Tokito, Mariko K ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; MICROTUBULE ASSOCIATED PROTEIN; POLYPEPTIDE; PROTEIN P 150; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 2P; FLUORESCENCE IN SITU HYBRIDIZATION; GENE ISOLATION; HUMAN; LIMB GIRDLE MUSCULAR DYSTROPHY; MOLECULAR CLONING; PRIORITY JOURNAL;

CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 2; DYNEIN ATPASE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS;

EID: 0030023491     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0068     Document Type: Article

References (12)

1. Bashir, R., Strachan, T., Keers, S., Stephenson, A., Mahjneh, I., Marconi, G., Nashel, L., and Bushby, K. M. D. (1994). A gene for autosomal recessive limb-girdle muscular dystrophy maps to chromosome 2p. Hum. Mol. Genet. 3: 455-457.
2. Gill, S. R., Schroer, T. A., Szilak, I., Steuer, E. R., Sheetz, M. P., and Cleveland, D. W. (1991). Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J. Cell Biol. 115: 1639-1650.
3. Holzbaur, E. L. F., Hammarback, J. A., Paschal, B. M., Kravit, N. G., Pfister, K. K., and Vallee, R. B. (1991). Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature 351: 579-583.
4. Holzbaur, E. L. F., and Vallee, R. B. (1994). Dyneins: Molecular structure and cellular function. Annu. Rev. Cell Biol. 10: 339-372.
5. Jones, J. M., Albin, R. L., Feldman, E. L., Simin, K., Schuster, T. G., Dunnick, W. A., Collins, J. T., Chrisp, C. E., Taylor, B. A., and Meisler, M. H. (1993). mnd2: A new mouse model of inherited motor neuron disease. Genomics 16: 669-677.
6. Karki, S., and Holzbaur, E. L. F. (1995). Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex. J. Biol. Chem. 270: 28806-28811.
7. Glued component of the dynactin complex in developing and adult rat brain. J. Comp. Neurol. 357: 15-24.
8. Schafer, D. A., Gill, S. R., Cooper, J. A., Heuser, J. E., and Schroer, T. A. (1994). Ultrastructural analysis of the dynactin complex: An actin-related protein is a component of a filament that resembles F-actin. J. Cell Biol. 126: 403-412.
9. Spurr, N. K., Barton, H., Bashir, R., Bryson, G. M., Bushby, K., Cox, S., Gringrich, J. C., Hentati, A., Hildebrandt, F., Kao, F.-T., Kruse, T., Lai, E., Liu, J., Menke, M., Naylor, S., Nicklin, M., Read, A., Reiner, O., Rocchi, M., and Summar, M. (1994). Report of the third international workshop on human chromosome 2 mapping 1994. Cytogenet. Cell Genet. 67: 216-244.
10. Swaroop, A., Sun, J.-W., Paco-Larson, M. L., and Garen, A. (1986). Molecular organization and expression of the genetic locus Glued in Drosophila melanogaster. Mol. Cell. Biol. 6: 833-841.
11. Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp1). Proc. Natl. Acad. Sci. USA 92: 1634-1638.
12. Waterman-Storer, C. M, Kuznetsov, S. A., Karki, S., Langford, G. M., Weiss, D. G., and Holzbaur, E. L. F. (1995b). Disruption of the dynein-dynactin interaction inhibits axonal transport in extruded squid axoplasm. In "The Cytoskeleton and Cell Function," Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.