The female 'insulin advantage' in a biracial cohort: Results from the Miami Community Health Study

International Journal of Obesity

Volumn 20, Issue 1, 1996, Pages 76-82

  Donahue, R P ^a   Prineas, R J ^a   DeCarlo Donahue, R ^b   Bean, J A ^a   Skyler, J S ^c  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c Department of Biology   (United States)

Author keywords

Body fat; Gender; Insulin

Indexed keywords

GLUCOSE; INSULIN;

ADULT; ARTICLE; BODY FAT; CAUCASIAN; COHORT ANALYSIS; ETHNIC GROUP; FEMALE; HUMAN; INSULIN SENSITIVITY; MALE; MULTIVARIATE ANALYSIS; NEGRO; NORMAL HUMAN; PRIORITY JOURNAL; PUBLIC HEALTH; SEX DIFFERENCE; UNITED STATES;

ADIPOSE TISSUE; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; BLOOD GLUCOSE; BODY COMPOSITION; BODY CONSTITUTION; BODY MASS INDEX; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FLORIDA; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN; MALE; SEX CHARACTERISTICS;

EID: 0030023381     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Wingard DL, Suarez L, Barrett-Connor E. The sex differential in mortality from all causes and ischemic heart disease. Am J Epidemiology 1983; 117: 165-172.
2. Vebrugge LM. Sex differentials in morbidity and mortality in the United States. Soc Biology 1976; 23: 275-296.
3. Wingard DL. The sex differential in mortality rates: demographic and behavioral factors. Am J Epidemiology 1982; 115: 205-216.
4. Kannel WB, McGee DL. Diabetes and glucose tolerance as risk factors for cardiovascular disease: the Framingham study. Diabetes Care 1979; 2(2): 120-126.
5. Heyden S, Heiss G, Bartel AG, Hames CG. Sex differences in coronary mortality among diabetics in Evans County, Georgia. J Chron Dis 1980; 33: 265-273.
6. Pan W-H, Cedres LB, Liu K, Dyer A, Schoenberger JA, Shekelle RB, Stamler R, Smith D, Collette P, Stamler J. Relationship of clinical diabetes and asymptomatic hyperglycemia to risk of coronary heart disease mortality in men and women. Am J Epidemiology 1985; 121: 541-547.
7. Barrett-Connor E, Cohn BA, Wingard DL, Edelstein SL. Why is diabetes mellitus a stronger risk factor for fatal ischemic heart disease in women than men? JAMA 1991; 265: 627-631.
8. Pyorala K. Relationship of glucose tolerance and plasma insulin in the incidence of coronary heart disease: results from two population studies in Finland. Diabetes Care 1979; 19: 205-210.
9. Fontbonne A, Charles MA, Thibult N, Richard JL, Claude JR, Warnet JM, Rosselin GE, Eschwege E. Hyperinsulinemia as a predictor of coronary heart disease mortality in a healthy population: the Paris Prospective Study, 15 year follow-up. Diabetelogia 1991; 34: 356-361.
10. Welborn TA, Wearne K. Coronary heart disease incidence and cardiovascular mortality in Busselton with reference to glucose and insulin concentrations. Diabetes Care 1979; 2: 154-160.
11. Orchard TJ, Eichner J, Kuller LH, Becker DJ, McCallum LM, Grandits GA. Insulin as a predictor of coronary heart disease: interaction with Apolipoprotein E phenotype. Ann Epidemiol 1994; 4: 40-45.
12. Welin L, Erikson H, Larsson B, Ohlson L-O, Svardsuud K, Tibbin G. Hyperinsulinemia is not a major coronary risk factor in elderly men. The study of men born in 1913. Diabetelogia 1992; 35: 766-770.
13. Ferrara A, Barrett-Connor EL, Edelstein SL. Hyperinsulinemia does not increase the risk of fatal cardiovascular disease in elderly men or women without diabetes: the Rancho Bernardo Study, 1984 1991. Am J Epidemiol 1994; 140: 857-869.
14. Orchard TJ, Becker DJ, Kuller LH, Wagener D, LaPorte RE, Drash AI. Age and sex variations in glucose tolerance and insulin responses: parallels with cardiovascular risk. J Chronic Dis 1982; 35: 123-132.
15. Donahue RP, Orchard TJ, Becker DJ, Kuller LH, Drash AL. Sex differences in the coronary heart disease profile: a possible role for insulin. The Beaver County Study. Am J Epidemiology 1987; 125: 650-657.
16. Boyns DR, Crossley JN, Abrams ME, Jarrett RJ, Keen H. Oral glucose tolerance and related factors in a normal population sample - I. Blood sugar, plasma insulin, glyceride, cholesterol measurements and the effect of age and sex. Br Med J 1969; 1: 595-598.
17. Welborn TA, Stenhouse NS, Johnstone CG. Factors determining serum-insulin response in a population sample. Diabetologia 1969; 5: 263-266.
18. Pedersen O, Hjøllund E, Lindskov HO. Insulin binding and action on fat cells from young healthy females and males. Am J Physiology 1982; 243: E158-167.
19. Foley JE, Kashiwagi A, Chang H, Huecksteadt TP, Lillioja S, Verso MA, Reaven G. Sex differences in insulin-stimulated glucose transport in rat and human adipocytes. Am J Physiology 1984; 246: E211-E215.
20. Yki-Järvinen H. Sex and insulin sensitivity. Metabolism 1984; 33: 1011-1015.
21. Hale PJ, Wright JV, Nattrass M. Differences in insulin sensitivity between normal men and women. Metabolism 1985; 34: 1133-1138.
22. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: A method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237: E214-E223.
23. World Health Organization. Diabetes mellitus - Report of a WHO study group. Publication No. 727 WHO: Geneva, Switzerland, 1985.
24. Durnin JUGA, Womersley J. Body fat assessed from total body density and its estimation from skinfold thicknesses: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 1974; 32: 77-97.
25. Siri WE. Body composition from fluid spaces and density: analysis of methods. In: Techniques for measuring body composition. National Academy of Sciences, National Research Council: Washington DC: 1961, pp 223-244.
26. Schutte JE, Townsend EJ, Hugg J, et al. Density of lean body mass is greater in blacks than in whites. J Appl Physiol 1984; 56: 1647-1649.
27. Gray DS, Bray GA, Gemayel N, Kaplan K. Effect of obesity on bioelectric impedance. Am J Clin Nutr 1989; 50: 255-260.
28. Yki-Järvinen H. Action of insulin on glucose metabolism in vivo. Clin Endocrinol Metab 1993; 7: 903-928.
29. Herbert V, Lau KS, Gottlieb CW. Coated charcoal immunoassay of insulin. J Clin Endocrin 1965; 25: 1375-1384.
30. SAS Institute Inc. SAS user's guide: statistics, version 5. SAS Institute: Cary NC, 1985.
31. Paffenbarger Jr RS, Wing AL, Hyde RT. Physical activity as an index of heart attack risk in college alumni. Am J Epidemiology 1978; 108: 161-175.
32. Ferraninni E, Bjorkman O, Reichard GA, Pilo A, Olsson M, Wahren J, DeFronzo RA. The disposal of an oral glucose load in healthy subjects. A quantitative study. Diabetes 1985; 35: 580-588.
33. Lillioja S, Bogardus C. Obesity and insulin resistance. Lessons learned from the Pima Indians. Diabetes/Metab Rev 1988; 4: 517-540.
34. Bogardus C, Lillioja S, Mott M, Hollenbeck C, Reaven G. Relationship between degree of obesity and in-vivo insulin action in man. Am J Physiol 1985; 248: 286-291.
35. Nuutila P, Knuuti MJ, Mäki M, Laine H, Ruotsalaninen U, Teräs M, Haapuranta M, Solin O, Yki-Järvinen H. Gender and insulin sensitivity in the heart and in skeletal muscles. Studies using position emission tomography. Diabetes 1995; 44: 31-36.
36. Lillioja S, Young AA, Zawadzki JK, Yki-Järvinen H, Christin L, Secomb TW, Bogardus C. Skeletal muscle capillary density and fiber type are possible determinants of in-vivo insulin resistance in man. J Clin Invest 1987; 80: 415-424.
37. Holmäng A, Brzezinska Z, Bjöotorp P. Effects of hyperinsulinemia on muscle fiber composition and capillarization in rats. Diabetes 1993; 42: 1073-1081.
38. Goldzieher J, Young RL. Selected aspects of polycystic ovarian disease. Endocrinol Metab Clin North Am 1992; 21: 141-171.
39. Bailey CJ, Sorour-Ahmed H. Role of ovarian hormones in the long-term control of glucose homeostasis. Effects on insulin secretion. Diabetelogia 1980; 19: 475-481.
40. Haffner SM, Mykkänen L, Stern MP, Valdez RA, Heisserman JA, Bowsher RR. Relationship of proinsulin and insulin to cardiovascular risk factors in nondiabetic subjects. Diabetes 1993; 42: 1297-1302.
41. Kissebah AH, Vydelingum N, Murray R, Evans DJ, Hartz AJ, Kalkohoff RH, Adams PW. Relation of body fat distribution to metabolic complications of obesity. J Clin Endoc Metab 1982; 54: 254-260.
42. Peiris AN, Struve MF, Kissebah AH. Relationship of body fat distribution to the metabolic clearance of insulin in premenopausal women. Int J Obesity 1987; 11: 581-589.
43. Krotkiewski M, Bjorntorp P, Sjostrom L, Smith U. Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. J Clin Invest 1983; 72: 1150-1162.
44. Vague J. The degree of masculine differentiation of obesities: a factor predisposing to diabetes, atherosclerosis, gout and uric-calculous disease. Am J Clin Nutr 1956; 4: 20-34.
45. Evans DJ, Hoffman RG, Kalkhoff RK, Kissebah AH. Relationship of androgenic activity to body fat topography, fat cell morphology and metabolic aberrations in premenopausal women. J Clin Endocrin Metab 1983; 57: 304-309.
46. Lillioja S, Mott DM, Zawadski JK, Young AA, Abbott WHG, Knowler WC, Bennett PH, Moll P, Bogardus C. In-vivo insulin action is a familial characteristic in nondiabetic Pima Indians. Diabetes 1987; 36: 1329-1335.