Liposomal ATP protects the liver from injury during shock

European Surgical Research

Volumn 28, Issue 2, 1996, Pages 140-145

  Konno, H ^a   Matin, A F M ^a   Maruo, Y ^a   Nakamura, S ^a   Baba, S ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ATP; Liposomes; Reperfusion; Shock

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DRUG CARRIER; LACTATE DEHYDROGENASE; LIPOSOME; LIVER ENZYME;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD FLOW VELOCITY; CONTROLLED STUDY; ENZYME BLOOD LEVEL; HYPOVOLEMIC SHOCK; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER BLOOD FLOW; LIVER INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION;

EID: 0030023103     PISSN: 0014312X     EISSN: 14219921     Source Type: Journal    
DOI: 10.1159/000129451     Document Type: Article

References (15)

1. Färber JL, Chien KR, Miunachl S Jr: The pathogenesis of irreversible cell injury in ischemia. Am J Pathol 1981;102:271-281.
2. Marubayashi S, Dohi K, Ezaki H, Hayashi K, Kawasaki T: Preservation of ischemic rat liver mitochondrial functions and liver viability with CoQ 10. Surgery 1982:91:631-637.
3. Nordstrom G, Seeman T, Hasselgren P-O: Beneficial effect of allopu-rinol in liver ischemia. Surgery 1985:97:679-683.
4. Granger DN: Role of xanthine oxidase and granulocytes in ischentia-reperfusion injury. Am J Physiol 1988;255:H1269-H1275.
5. Gregoriadis G: The liposomes drug-carricr concept: Its development and future; in Gregoriadis G. Allison AC (eds): Liposomes in Biological Systems. New York, Wiley, 1980. pp 25-86.
6. Konno H, Suzuki H, Tadakuma T, Kumai K, Yasuda T, Kubota T, Ohta S, Nagaike K. Hosokawa S. Ishibiki K, Abe O. Saito K: Antitumor effect of adriamvein enlrapped in liposomes conjugated with antihuman α-fetoprotein monoclonal antibody. Cancer Res 1987,47: 4471-4477.
7. Konno H, Maruo Y, Matin AF, Tanaka T, Oakamura S, Baba S, Ya-mashita A, Tadakuma T: Effect of liposomal interleukin-2 on ascites-forming rat hepatoma. J Surg Oncol 1992;51:33-37.
8. Guo-Xing Xu, Xing-Hui X, Fang-Yu L, De-Liang Z, Dao-Sheng Z, Ding-Jiu H, Ming-Xin H: Adenosin triphosphate liposomes: Encapsulation and distribution studies. Pharm Res 1990;7:553-557.
9. Williams D, Riebel D, Rovetto MJ: ATP induced increase in ATP content of cultured myocardial cells (abstract). Fed Proc 1979;38:1389.
10. Zicgclhoffcre A, Fedelesova M, Kostolansky S: Specific ATP action on the metabolism of isoaltcd heart: Influence of pH. divalent cation concentration and stability of complexes. Acta Biol Med Germ 1972:8: 893-900.
11. Clements MG, McDonagh PF, Chaudry IS, Baue AE: Hepatic microcirculatory failure after ischemia and reperfusion: Improvement with ATP-MgCL treatment. Am J Physiol 1985;248:H804-H811.
12. Ohkawa M, Clemens MG, Chaudry IH: Studies on the mechanism of beneficial effects of ATP-MgCL following hepatic ischemia. Am J Physiol 1983;244:R965-R702.
13. Wang P, Ba ZF, Dean RE, Chaudry IH: ATP-MgCL restores the hepatocellular function and hepatic blood flow following hemorrhage and resuscitation. Surg Res 1991:50:358-374.
14. Chaudry IH: Cellular mechanisms in shock and ischemia and their correction. Am J Physiol 1983:245: R117-R134.
15. 14C]triglyceride-entrapped laclosylccramide-bearing liposomes after intravenous injection into mouse. Chem Pharm Bull (Tokyo) 1992,40:1016.