Suppression of plasma estradiol and progesterone concentrations by buthionine sulfoximine in female rats

Biochemical Pharmacology

Volumn 51, Issue 4, 1996, Pages 567-570

  Kang, Y James ^a   Uthus, Eric O ^b  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b NONE

Author keywords

buthionine sulfoximine; estradiol; glutathione; ovary; progesterone

Indexed keywords

ALKALINE PHOSPHATASE; BUTHIONINE SULFOXIMINE; CERULOPLASMIN; CHOLESTEROL; CREATINE; CREATININE; ESTRADIOL; GLUCOSE; GLUTATHIONE; HEMOGLOBIN; LIOTHYRONINE; PROGESTERONE; PROLACTIN; THYROXINE; TRIACYLGLYCEROL; UREA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; FEMALE; HEMATOCRIT; HORMONE BLOOD LEVEL; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; NONHUMAN; OVARY; PRIORITY JOURNAL; RAT; TISSUE LEVEL;

EID: 0030022889     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02221-X     Document Type: Article

References (16)

1. Meister A, Metabolism and function of glutathione. In: Glutathione: Chemical, Biochemical, and Medical Aspects, Part A (Eds. Dolphin D, Poulson R and Avramovie O), pp. 367-474. John Wiley, New York, 1989.
2. Griffith OW, L-Buthionine-SR-sulfoximine: Mechanism of action, resolution of diastereomers and use as a chemotherapeutic agent. In: Glutathione Centennial: Molecular Perspectives and Clinical Implication (Eds. Taniguchi N, Higashi T, Sakamoto Y and Meister A), pp. 258-299. Academic Press, New York, 1989.
3. Biaglow JE, Varnes ME, Clark EP and Epp ER, The role of thiols in cellular response to radiation and drugs. Radiat Res 95: 437-455, 1983.
4. Russo A and Mitchell JB, Potentiation and protection of doxorubicin cytotoxicity by cellular glutathione modulation. Cancer Treat Rep 69: 1293-1296, 1985.
5. Bailey HH, Mulcahy RT, Tutsch KD, Arzoomanian RZ, Alberti D, Tombes MB, Wilding G, Pomplun M and Spriggs DR, Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: An attempt at modulation of glutathione. J Clin Oncol 12: 194-205, 1994.
6. Uthus EO, Diethyl maleate, an in vivo chemical depletor of glutathione, affects the response of male and female rats to arsenic deprivation. Biol Trace Elem Res 46: 247-259, 1994.
7. Skapek SX, Colvin OM, Griffith OW, Elion GB, Bigner DD and Friedman HS, Enhanced melphalan cytotoxicity following buthionine sulfoximine-mediated glutathione depletion in a human medulloblastoma xenograft in athymic mice. Cancer Res 48: 2764-2767, 1988.
8. Lehmann HP, Schosinsky KH and Beeler MF, Standardization of serum ceruloplasmin concentrations in International Enzyme Units with o-dianisidine dihydrochloride as substrate. Clin Chem 20: 1564-1567, 1974.
9. Reed DJ, Babson JR, Beatty PW, Brodie AE, Ellis WW and Potter DW, High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides. Anal Biochem 106: 55-62, 1980.
10. Kang YJ, Feng Y and Hatcher EL, Glutathione stimulates A549 cell proliferation in glutamine-deficient culture: The effect of glutamate supplementation. J Cell Physiol 161: 589-596, 1994.
11. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ and Klenk DC, Measurement of protein using bicinchoninic acid. Anal Biochem 150: 76-85, 1985.
12. Miller WR, Endocrine treatment for breast cancers: Biological rationale and current progress. J Steroid Biochem Mol Biol 37: 467-480, 1990.
13. Theriault RL and Sellin RV, Estrogen-replacement therapy in younger women with breast cancer. Monogr Natl Cancer Inst 16: 149-152, 1994.
14. Brzezinski A, Management of menopause in women with breast cancer. Isr J Med Sci 31: 163-168, 1995.
15. Schwartz J, Freeman R and Frishman W, Clinical pharmacology of estrogen: Cardiovascular actions and cardioprotective benefits of replacement therapy in postmenopausal women. J Clin Pharmocol 35: 314-329, 1995.
16. Kang YJ and Enger MD, Buthionine sulfoximine induced cytostasis does not correlate with glutathione depletion. Am J Physiol 262: C122-C127, 1992.