Hyperfractionated conformal radiotherapy in locally advanced prostate cancer: Results of a dose escalation study

International Journal of Radiation Oncology Biology Physics

Volumn 34, Issue 3, 1996, Pages 655-662

  Forman, Jeffrey D ^a   Duclos, Marie ^a   Shamsa, Falah ^a   Porter, Arthur T ^a   Orton, Colin ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

Dose escalation; Hyperfractionation; Locally advanced prostate cancer

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; FOLLOW UP; GASTROINTESTINAL TOXICITY; HUMAN; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROSTATE BIOPSY; PROSTATE CANCER; RADIATION DOSE FRACTIONATION; RADIATION INJURY; UROGENITAL TRACT DISEASE;

EID: 0030022765     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(95)02202-3     Document Type: Article

References (24)

1. Bagshaw, M. A. Current conflicts in the management of prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 12:1721-1727; 1986.
2. Brindle, J. S.; Martinez, A.; Schray, M.; Edmundson, G.; Benson, R. C.; Zincke, H.; Diokno, A.; Gonzalez, J. Pelvic lymphadenectomy and transperineal interstitial implantation of IR 192 combined with external beam radiotherapy for bulky stage C prostatic carcinoma. Int. J. Radiat. Oncol. Phys. 17:1063-1066; 1989.
3. Edsmyr, F.; Andersson, L.; Esposti, P.L.; Littbrand, B.; Nilsson, B. Irradiation therapy with multiple small fractions per day in urinary bladder cancer. Radiother. Oncol. 4:197-203; 1985.
4. Forman, J. D.; Orton, C.; Ezzell, G.; Porter, A. T. Hyperfractionated three dimensional conformal radiotherapy for locally advanced adenocarcinoma of the prostate: Preliminary results of a biologic dose escalation study. J. Radiother. Oncol. 27:203-208; 1993.
5. Fowler, J. F.; Ritter, M. A rationale for fractionation for slowly proliferating tumors such as prostatic adenocarcinoma. Int. J. Radiat. Oncol. Biol. Phys. 32:521-529; 1995.
6. Fuks, Z.; Whitmore W. F.; Leibel, S.; Nori, D.; Hilaris, B. Local control is associated with decreased distant failure in early stage carcinoma of the prostate. Int. J. Radiat. Oncol. Biol. Phys. 17(Supp 1):121; 1989.
7. Freiha, F. S.; Bagshaw, M. A. Carcinoma of the prostate: Results of post-irradiation biopsy. Prostate 5:19-25; 1984.
8. Hanks, G. E.; Lee, W. R.; Corn, B.; Schultheiss, T. E. Response to "only 20% of irradiated prostate cancer patients are cured and the remainder may be made worse." Int. J. Radiat. Oncol. Biol. Phys. 30:217; 1994.
9. Hanks, G. E.; Martz K. L.; Diamond, J. J. The effect of dose on local control of prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 15:1299-1305; 1988.
10. Kaplan, E.L.; Meier, P. Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc. 53:457-481; 1958.
11. Kuban, D.; El-Mahdi, A. M.; Schellhammer, P. F. Effect of local tumor control on distant metastasis and survival in prostatic adenocarcinoma. Urology 30:420-426; 1987.
12. Liebel S. A.; Kutcher, G. J.; Mohan, R.; Harrison L. B.; Armstrong, J. G.; Zelefsky, M. J.; LoSasso, T. J.; Burman, C. M.; Mageras, G. S.; Chui, C. S.; Brewster, L. J.; Masterson, M. E.; Lo, Y. C.; Ling, C. C.; Fuks, F. Three-dimensional conformal radiation therapy at the Memorial Sloan Kettering Cancer Center. Semin. Radiat. Oncol. 2(4):274-289; 1992.
13. Perez, C. A.; Garcia, D.; Simpson, J. R.; Zivnuska, F.; Lockett, M. A. Factors influencing outcome of definitive radiotherapy for localized carcinoma of the prostate. Radiother. Oncol. 16:1-21; 1989.
14. Pilepich, M.; Sause, W.; Shipley, W. U.; Krall, J. M. Androgen deprivation with radiation therapy compared with radiation therapy alone for locally advanced prostatic carcinoma: A randomized comparative trial of the raidaiton therapy oncology group. Urology 45:4; 1995.
15. Porter, A. T.; Forman, J. D. Prostate Brachytherapy: An overview. Cancer 71:950-958; 1993.
16. Russell, K. J.; Caplan, R. J.; Laramore, G. E.; Burnison, C. M.; Maor, M. H.; Taylor, M. E.; Zink, S.; Davis, L. W.; Griffin, T. W. Photon vs. fast neutron external beam radiotherapy in the treatment of locally advanced prostate cancer: Results of a randomized prospective trial. Int. J. Radiat. Onc. Biol. Phys. 28:47-54; 1994.
17. Sandler, H.; McLaughlin, W.; Ten Haken, R.; Addison, H.; Forman, J. D.; Lichter, A. 3D Conformal radiotherapy for the treatment of prostate cancer: Low risk of chronic rectal morbidity observed in a large series of patients. I. J. Radiat. Oncol. Biol. Phys. 27 (Supp 1): 135, 1993.
18. Sandler, H. M.; Perez-Tamayo, C.; Ten-Haken, R. K.; Lichter, A. S. Dose escalation for stage C (T3) prostate cancer: Minimal rectal toxicity observed using conformal therapy. Radiother. Oncol. 23:53-54; 1991.
19. Schultheiss, T. E.; Hanks, G.; Hunt, M. A.; Lee, W. R. Incidence of and factors related to late complications in conformal and conventional radiation treatment of cancer of the prostate. Int. J. Radiat. Oncol. Biol. Phys. 32:643-649; 1995.
20. Shipley, W. U.; Prout, G. R.; Coachman, N. M.; McManus, P. L.; Healey, E. A.; Althausen, A. F.; Heney, N. M.; Parkhurst, E. C.; Young H. H., II.; Shipley, W.; Kaufman, S. D. Radiation therapy for localized prostate carcinoma: Experience at the Massachusetts General Hospital (1973-1981). NCI Monograph 7:67-73; 1988.
21. Shipley, W. U.; Verhey, L. J.; Munzenrider, J. E.; Suit, H. D.; Urie, M. M.; McManus, P. L.; Young, R. H.; Shipley, J. W.; Zietman, A. L.; Biggs, P. J.; Heney, N. M.; Goitein, M. Advanced prostate cancer: The results of a randomized comparative trial of high dose irradiation boosting with conformal protons compared with conventional dose irradition using photons alone. Int. J. Radiation Oncology Biol. Phys. 32:3-12; 1995.
22. Thames, H. D., Jr.; Withers, H. R.; Peters, L. J.; Flectcher, G. H. Changes in early and late radiation responses with altered dose fractionation: Implications for dose-survival relationships. Int. J. Radiat. Oncol. Biol. Phys. 8:219-226; 1982.
23. Zagars, G. K.; von Eschenbach, A. C.; Johnson, D. E.; Oswald, M. J. Stage C adenocarcinoma of the prostate: An analysis of 551 patients treated with external beam radiation. Cancer 60:1489-1499; 1987.
24. Zeitman, A. L.; Shipley, W. U.; Coen, J. J. Prostate: New insights into outcome from repeat biopsy and prostate specific antigen followup. J. Urol. 5:1806-1815; 1993.