Evidence favoring molybdenum-carbon bond formation in xanthine oxidase action: 17O- and 13C-ENDOR and kinetic studies

Biochemistry

Volumn 35, Issue 5, 1996, Pages 1432-1443

  Howes, Barry D ^a,b   Bray, Robert C ^a   Richards, Raymond L ^a,c   Turner, Nigel A ^a   Bennett, Brian ^a   Lowe, David J ^a,c  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY OF FLORENCE   (Italy)

^c JOHN INNES CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 METHYLPURINE; CARBON; CARBON 13; MOLYBDENUM; OXIPURINOL; OXYGEN; OXYGEN 17; OXYGEN 18; SULFUR; UNCLASSIFIED DRUG; URIC ACID; XANTHINE; XANTHINE OXIDASE;

ANISOTROPY; ARTICLE; ELECTRON SPIN RESONANCE; ENZYME MECHANISM; MASS SPECTROMETRY; OXIDATION; PRIORITY JOURNAL;

ANIMALS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME INHIBITORS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; METALLOPROTEINS; MILK; MODELS, CHEMICAL; MOLYBDENUM; OXYGEN ISOTOPES; OXYPURINOL; URIC ACID; XANTHINE OXIDASE;

EID: 0030022686     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9520500     Document Type: Article

References (72)

1. Bordas, J., Bray, R. C., Garner, C. D., Gutteridge, S., & Hasnain, S. S. (1980) Biochem. J. 191, 499-508.
2. Bray, R. C. (1975) Enzymes (3rd Ed.) 12, 299-420.
3. Bray, R. C. (1988) Q. Rev. Biophys. 21, 299-329.
4. Bray, R. C., & Gutteridge, S. (1982) Biochemistry 27, 5992-5999.
5. Bray, R. C., & George, G. N. (1985) Biochem. Soc. Trans. 13, 560-567.
6. Bray, R. C., Howes, B. D., Turner, N. A., Bennett, B., Richards, R. L. & Lowe, D. J. (1995) J. Inorg. Biochem. 59, 734.
7. Bray, R. C., Bennett, B., Burke, J. F., Chovnick, A., Doyle, W. A., Howes, B. D., Lowe, D. J., Richards R. L., Turner, N. A., Ventom, A., & Whittle, J. R. S. (1996) Biochem. Soc. Trans. 24, 99-105.
8. Brisdon, B. J., Hodgson, A. G. W., Mahon, M. F., & Molloy, K. C. (1993) J. Chem. Soc., Dalton Trans., 245-251.
9. Broker, D. C., Wiston, P. B., Tonker, T. L., & Templeton, J. L. (1986) Inorg. Chem. 25, 2883-2888.
10. Burrow, T. E., Hughes, D. L., Lough, A. J., Maguire, M. J., Morris, R. H., & Richards, R. L. (1995) J. Chem. Soc., Dalton Trans., 1315-1323.
11. Cammack, R., Chapman, A., McCracken, J., Cornelius, J. B., Peisach, J., & Weiner, J. H. (1988) Biochim. Biophys. Acta 956, 305-312.
12. Carmona, E., Sanchez, L., Martin, J. M., Povenda, M. L., Atwood, J. L., Priestar, R. D., & Rosers, R. D. (1984) J. Am. Chem. Soc. 106, 3214-3222.
13. Cotton, F. A., Troup, J. M., Webb, T. R., Williamson, D. H., & Wilkinson G. (1974) J. Am. Chem. Soc. 96, 3824-3828.
14. Coucouvanis, D., Toupadakis, A., Lane, J. D., Koo, S. M., Kim, C. G., & Hadjikyriacou, A. (1991) J. Am. Chem. Soc. 113, 5271-5282.
15. Cramer, S. P., & Hille, R. (1985) J. Am. Chem. Soc. 107, 8164-8169.
16. Cramer, S. P., Wahl, R., & Rajagopalan, K. V. (1981) J. Am. Chem. Soc. 103, 7721-7727.
17. Durfee, D. D., & Rothwell, I. P. (1988) Chem. Rev. 88, 1059-1079.
18. Edmondson, D., Massey, V., Palmer. G., Beecham, L. M., & Elion, G. B. (1970) J. Biol. Chem. 247, 1597-1604.
19. Enemark, J. H., & Young, C. G. (1993) Adv. Inorg. Chem. 40, 1-88.
20. von Felten, H., Wernli, B., & Gamsjäger, H. (1978) J. Chem. Soc., Dalton Trans., 496-500.
21. Gambarotta, S., Floriani, C., Chiesi-Villa, A., & Guastini, C. (1985) J. Am. Chem. Soc. 107, 2985-2986
22. George, G. N., & Bray, R. C. (1988) Biochemistry 27, 3603-3609.
23. Greenwood, R. J., Wilson, G. L., Pilbrow, J. R., & Wedd, A. G. (1993) J. Am. Chem. Soc. 115, 5385-5392.
24. Gutteridge, S., & Bray, R. C. (1980) Biochem. J. 189, 615-623.
25. Hanson, G. R., Wilson, G. L., Bailey, T. D., Pilbrow, J. R., & Wedd, A. G. (1987) J. Am. Chem. Soc. 109, 2609-2616.
26. Hart, L. I., McGartoll, M. A., Chapman, H. R., & Bray, R. C. (1970) Biochem. J. 116, 851-864.
27. Hawkes, T. R., George, G. N., & Bray, R. C. (1984) Biochem. J. 218, 961-968.
28. Hille, R. (1994) Biochim. Biophys. Acta 1184, 143-169.
29. Hille, R., & Massey, V. (1985) in Molybdenum Enzymes (Spiro, T. G., Ed.) pp 443-518, Wiley, New York.
30. Hille, R., & Sprecher (1987) J. Biol. Chem. 262, 10914-10917.
31. Hille, R., George, G. N., Eidsness, M. K., & Cramer, S. P. (1989) Inorg. Chem. 28, 4018-4022.
32. Hoffman, B. M., Martinsen, J., & Venters, R. A. (1984) J. Magn. Reson. 59, 110-123.
33. Holm, R. H. (1990) Coord. Chem. Rev. 100, 183-221.
34. Howes, B. D., Pinhal, N. M., Turner, N. A., Bray, R. C., Anger, G. Ehrenberg, A., Raynor, J. B., & Lowe, D. J. (1990) Biochemistry 29, 6120-6127.
35. Howes, B. D., Bennett, B., Lowe, D. J., & Bray, R. C. (1991a) in Flavins and Flavoproteins (Curti, B., Ronchi, S., & Zanetti, G., Eds.) pp 691-694 De Gruyter, Berlin.
36. Howes, B. D., Bennett, B., Koppenhöfer, A., Lowe, D. J., & Bray, R. C. (1991b) Biochemistry 30, 3969-3975.
37. Howes, B. D., Bennett, B., Bray, R. C., Richards R. L., & Lowe, D. J. (1994) J. Am. Chem. Soc. 116, 11624-11625.
38. Hughes, D. L., Marjani, K., & Richards, R. L. (1994) Abstracts of Papers, 16th International Conference on Organometallic Chemistry, University of Sussex, U.K., p 247.
39. Johnson, M. D., & Murmann, R. K. (1983) Inorg. Chem. 22, 1068-1072.
40. Kreissl, F. R., Sieber, W. J., Keller, H., Riede, J., & Wolfgruber, M. (1987) J. Organomet. Chem. 320, 83-90.
41. Lemos, M. A. N. D. A., Pombeiro, A. J. L., Hughes, D. L., & Richards, R. L. (1992) J. Organomet. Chem. 434, C6-C9.
42. Lippard, S. J., & Berg, J. M. (1994) Principles of Bioinorganic Chemistry, pp 318-324, University Science Books, Mill Vale, CA.
43. Lorigan, G. A., Britt, R. D., Kim, J. H., & Hille, R. (1994) Biochim. Biophys. Acta 1185, 284-294.
44. Lowe, D. J. (1995) ENDOR and EPR of Metalloproteins, Landes, Austin, TX.
45. Malthouse, J. P. G., & Bray, R. C. (1980) Biochem. J. 191, 265-267.
46. Malthouse, J. P. G., Williams, J. W., & Bray, R. C. (1981a) Biochem. J. 197, 421-425.
47. Malthouse, J. P. G., George, G. N., Lowe, D. J., & Bray, R. C. (1981b) Biochem. J. 199, 629-637.
48. McWhirter, R. B., & Hille, R. C. (1991) J. Biol. Chem. 266, 23724-23731.
49. Massey, V., Komai, H., Palmer, G., & Elion, G. B. (1970) J. Biol. Chem. 245, 2837-2844.
50. Morpeth, F. F., & Bray, R. C. (1984) Biochemistry 23, 1332-1338.
51. Morton, J. R., & Preston, K. F. (1978) J. Magn. Reson. 30, 577-582.
52. Müller, A., & Mohan, N. (1981) Z. Anorg. Allg. Chem. 480, 157-162.
53. Müller, A., Seger, U., & Werner, E. (1979) Inorg. Chim. Acta 32, L65-L66.
54. Murmann, R. K. (1980) Inorg. Chem. 19, 1765-1770.
55. Pick, F. M., McGartoll, M. A., & Bray, R. C. (1971) Eur. J. Biochem. 18, 65-72.
56. Pilato, R. S., & Stiefel, E. I. (1993) in Bioinorganic Catalysis (Reedijk, J., Ed.) pp 131-188, Dekker, New York.
57. Rajagopalan, K. V., & Johnson, J. L. (1992) J. Biol. Chem. 267, 10199-10202.
58. Rappé, A. K., & Goddard, W. A. (1982) J. Am. Chem. Soc. 104, 3287-3294.
59. Rodgers, K. R., Murmann, R. K., Schempler, O. E., & Shelton, M. E. (1985) Inorg. Chem. 24, 1313-1322.
60. Romão, M. J., Archer, M., Moura, I., Moura, J. J. G., LeGall, J., Engh, R., Schneider, M., Hof, P., & Huber, R. (1995) Science 270, 1170-1176.
61. Schrauzer, G. N., Schlemper, E. O., Lin, N. H., Wang, Q., Rubin, K., Zhang, X., Long, X., & Chin, S. C. (1986) Organometallics 5, 2452-2456.
62. Schweiger, A. (1982) Struct. Bonding 51, 1-119.
63. Snetsinger, P. A., Chasteen, N. D., & van Willigen, H. (1990) J. Am. Chem, Soc. 112, 8155-8160.
64. Tanner, S. J., Bray, R. C., & Bergmann, F. (1978) Biochem. Soc. Trans. 6, 1328-1330.
65. True, A. E., Nelson, M. J., Venters, R. A., Orme-Johnson, W. H., & Hoffman, B. M. (1988) J. Am. Chem. Soc. 110, 1935-1943.
66. Turner, N. A. (1988) D. Phil. Thesis, University of Sussex, U.K.
67. Turner, N. A., Bray, R. C., & Diakun G. P (1989) Biochem. J. 260, 563-571.
68. Ventom, A. M., Deistung, J., & Bray, R. C. (1988) Biochem. J. 255, 949-956.
69. Walborsky, E. G., Wigley, D. E., Rowland, E., Dewan, A. C., & Schrock, R. R. (1987) Inorg. Chem. 26, 1615-1621.
70. Williams, J. W., & Bray, R. C. (1981) Biochem. J. 195, 753-760.
71. Wilson, G. L., Greenwood, R. J., Pilbrow, J. R., Spence, J. T., & Wedd, A. G. (1991) J. Am. Chem. Soc. 113, 6803-6812.
72. Wootton, J. C., Nicolson, R. E., Cock, J. M., Walters, D. E., Burke, J. F., Doyle, W. A., & Bray, R. C. (1991) Biochim. Biophys. Acta 1057, 157-185.