Effect of overexpression of human Cu,Zn superoxide dismutase in transgenic mice on macrophage functions

Journal of Immunology

Volumn 156, Issue 4, 1996, Pages 1578-1586

  Mirochnitchenko, Oleg ^b   Inouye, Masayori ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE;

ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME SYNTHESIS; GENE EXPRESSION REGULATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROMOTER REGION; RESPIRATORY BURST; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; BLOOD BACTERICIDAL ACTIVITY; CELL NUCLEUS; DNA PRIMERS; DOWN SYNDROME; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NF-KAPPA B; NITRATES; NITRITES; PHAGOCYTOSIS; PHOSPHOTYROSINE; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 0030022578     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Harris, E. D. 1992. Regulation of antioxidant enzymes. FASEB J. 6:2675.
2. Badway, T , and M. Karnovsky. 1980. Active oxygen species and the functions of phagocytic leukocytes. Ann. Rev Biochem. 69.695.
3. Bargio, J. L., A. Ugazio, L. Nespoli, and R. Maccario. 1983. Down's syndrome: A model of immunodeficiency. Birth Defects 19:325.
4. Barkin, R M., W L. Weston, J. Humbert and K. Sunada. 1980. Phagocytic function m Down syndrome-II bactericidal activity and phagocytosis. J. Ment Defic. Res. 24:251.
5. Sinet, P. M., J. Couturier, B. Dutrillaux, M. Poissonnier, O. Raoul, M. Rethore, D. Allard, L Lejeune, and H. Jerome. 1976. Trisome 21 et Superoxide dismutase-1 (IPO-A): tenative de locallisation sur la sous bauole 21q22.1. Exp. Cell Res. 97.47.
6. Sherman, L., N Dafni, J. Lieman-Hurwitz, and Y. Groner 1983. Nucleotide sequence and expression of human chromosome 21-encoded superoxide dismutase mRNA. Proc. Natl. Acad. Sci. USA 80.5465.
7. Gauthier, C., M. Mehtali, and R Lathes 1989. A ubiquitous mammalian expression vector, pHMG, based on housekeeping gene promoter. Nucleic Acid Res. 17:83
8. Hogan, B., F. Costantini, and E. Lacy. 1986. Manipulating the Mouse Embryo, A Laboratory Manual Cold Spring Harbor, CSH, New York.
9. Chomczynski, P., and N. Sacchi. 1987 Single-step method of RNA isolation by acid guanidinium tniocyonate-phenol-chloroform extraction. Anal. Biochem. 162:156
10. Kroczek, R., and E. Siebert. 1990. Optimization of northern analysis by vacuum-blotting, RNA-transfer visualization, and ultraviolet fixation Anal. Biochem. 184:90.
11. Conrad, R E 1981 Induction and collection of peritoneal exudate macrophages. In Manual of macrophage methodology. Vol 13, Part 1 H. B. Herscowitz, H. Holden, J. Bellanti, and A. Ghaffar, eds. Marcell Dekker, Inc., New York and Basel.
12. Metcalf, J., T. Gallin, W. Nauseef, and R Root. 1986. Laboratory manual of neutrophil function Raven, New York.
13. Lowry, O. H., N Rosenbrough, A Farr, and R. Randall. 1951. Protein measurement with the folin reagent. J Biol. Chem. 193:265.
14. Oyanagui, Y. 1984. Reevaluation of assay methods and establishment of kit for superoxide dismutase activity. Anal Biochem 142:290
15. Beauchamp, C . and I. Fridovich 1971. Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal Biochem. 44:276.
16. Moore, L L , and J Humbert. 1986 Intracellular killing of bacteria and fungi. Methods Enzymol. 132:520.
17. Weir, D., L. Hersenberg, and C. Blackwell. 1986. Handbook of Experimental Biology, Cellular Immunity 2:46.1
18. Harkonen, M., and F. Kauffman. 1973. Metabolic alternations in the axotomized superior cervical ganglion of the rat energy metabolism Brain Res. 65 127.
19. - secreted by monocytes and macrophages. Methods Enzymol. 105:365.
20. Pick, E. 1986. Microassays for Superoxide and hydrogen peroxide production and nitroblue tetrazolium reduction using enzyme immunoassay microplate reader. Methods Enzymol. 132 407.
21. Cathart, R., E. Schwiers, and B. Ames. 1983. Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. Anal Biochem. 134:111
22. Klebanoff, S 1993. Reactive nitrogen intermediates and antimicrobial activity: role of nitrite Free Rad. Biol Med. 14:351.
23. Schraufstatter, I., W. Halsey, P. Hyslop, and C. Cochrane. 1988. In vitro models for the study of oxidant-induced injury of cells in inflammation Methods Enzymol. 163 328.
24. Laemmli, U. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227:680
25. Andrews, N., and D V. Fallen 1991. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nicleic Acidas Res 19:2499.
26. Hyslop, P., D Hinshaw, W. Halsey, I. Schraufstatter, R Sauerheber, R. Spragg, J. Jackson, and C. Cochrane 1988. Mechanisms of oxidant-mediated cell injury. J Biol Chem 263 1665
27. Nathan, C., and J Hibbs. 1991 Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opin Immunol 3.65
28. Liew, F , and F. Cox. 1991. Nonspecific mechanism, the role of nitric oxide Immunol Today 12:A7.
29. Weinstein, S , J. Sanghera, K. Lemke, A. DeFranco and S. Pelech 1992. Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages. J. Biol. Chem. 267:14955.
30. Azuma, E., S. Kitagawa, A. Yuo, H. Mizoguchi, K. Umezawa, F Takaku, and M Saito 1993. Activation of the respiratory burst and tyrosine phosphorylation of proteins in human neutrophils, no direct relationship and involvement of protein kinase C-dependent and -independent signaling pathways. Biochim. Biophys. Acta 1179:213
31. Lenard, M , and D Baltimore. 1988. NF-κB; a pleiotropic mediator of inductible and tissue-specific gene control. Cell 58:227.
32. Baeuerle, P. 1991. The inducible transcription activator NF-κB: regulation by distinct protein subunits. Biochim. Biophys. Acta 1072:63.
33. Portnoy, D 1992. Innate immunity to a facultative intracellular bacterial pathogen. Current Opin. Immunol. 4:20
34. Oosting, R , L. Van Bree, J. Van Iwaarden, L Van Golde, and J. Verhoef. 1990. Impairment of phagocytic functions of alveolar macrophages by hydrogen peroxide. Am. J. Physiol. 259:L87
35. Epstein, C , K. Avraham, M Lovett, S. Smith, O. Elroy-Stein, G. Rotman, C. Bry, and Y Groner 1987 Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome. Proc. Natl. Acad. Sci. USA 84:8044.
36. Ceballos, I., A. Nicole, P. Briand, G. Grimper, A. Delacourte, S. Flament. J Blouin, M. Theverin, P. Kamoun and P. Sinet 1991. Expression of human Cu/Zn Superoxide dismutase gene in transgenic mice: model for gene dosage effect in Down syndrome Free Rad. Res Comms. 12:581
37. Tsunawaki, S., and C. Nathan. 1983. Enzymatic basis of macrophage activation. J. Biol. Chem. 258:4305.
38. Devary, V., Gottlieb, R., Smeal, T., and M. Karin. 1992. The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 71:1081.
39. Bauskin, A., I. Alkalay, and Y. Ben-Neriah 1991. Redox regulation of a protein tyrosine kinase in the endoplasmatic reticulum. Cell 66:685.
40. Keyse, S., and E Emslie. 1992. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. Nature 359:644.
41. Karin, M., and T. Smeal. 1992. Signal transduction pathways: the beginning of the end TIBS 17:418.
42. Schreck, R., P. Rieber, and P. Baeuerle. 1991. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-I. EMBO J 10:2247.
43. Schenk, H., M. Klein, W. Erdbrugger, W. Droge, and K. Schulze-Osthoff. 1994. Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1. Proc. Natl. Acad. Sci. USA 91.1672.
44. Anderson, M., Staal, F , Gitler, C., Herzenberg, L., and L. Herzenberg. 1994. Separation of oxidant-initiated and redox-regulated steps in the NFκB signal transduction pathway Proc. Natl. Acad. Sci. USA 91:11527.
45. Fialkow, L , C. Chan, S. Grinstein, and G. Downey. Regulation of tyrosine phosphorylation in neutrophils by the NADPH oxidase J. Biol. Chem. 268.17131.
46. Levin, S. 1987. The immune system and susceptibility to infection in Down's syndrome. Prog Clin. Biol. Res. 246:143
47. Anneren, G., and K. Bjorkstein. 1984. Low superoxide levels in blood phagocytic cells in Down's syndrome. Acta Pediatr. Scand. 73:345
48. Yavuzyilmaz, E , F Ersoy, O. Sanal, I. Tezcan, and D. Ercal. 1993. Neutrophil chemotaxis and periodontal status in Down's syndrome patients J. Nihon Univ. Sch. Dent. 33:91.
49. Novo, E., M. Garcia, and J Lavergne. 1993. Nonspecific immunity in Down syndrome, a study of chemotaxis, phagocytosis, oxidative metabolism and cell surface marker expression of polymorphonuclear cells. Am. J. Med Genet 46. 384.
50. Wysocki, H., J. Wysocki, and B Wierusz-Wysocka. 1987. The influence of thymus extract on the phagocytosis and the bactericidal capacity of polymorphonuclear neutrophils from children with Down's syndrome. Ann. NY Acad. Sci. 496: 740.