Design and synthesis of ring-constrained boropeptide thrombin inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 3, 1996, Pages 295-300

  Fevig, John M ^a   Abelman, Matthew M ^a,b   Brittelli, David R ^a,c   Kettner, Charles A ^a   Knabb, Robert M ^a   Weber, Patricia C ^a,d  

^a DUPONT COMPANY   (United States)

^b Dendreon   (United States)

^c BAYER CORPORATION   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLPROPIONIC ACID DERIVATIVE; BORON DERIVATIVE; BORONAMINO ACID DERIVATIVE; GROWTH HORMONE; THROMBIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME BINDING; X RAY ANALYSIS;

EID: 0030022189     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00015-7     Document Type: Article

References (22)

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22. Information regarding the coordinates, thermal parameters, distances and angles for the X-ray crystal structure of 23 is available from the authors.