Brefeldin A inhibition of apical Na+ channels in epithelia

American Journal of Physiology - Cell Physiology

Volumn 270, Issue 1 39-1, 1996, Pages

  Fisher, Richard S ^a   Grillo, F Gregory ^b   Sariban Sohraby, Sarah ^b  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b NONE

Author keywords

A6 cells; aldosterone; current fluctuation analysis; electrical; Golgi; noise; protein trafficking

Indexed keywords

ALDOSTERONE; AMILORIDE; AMILORIDE DERIVATIVE; BENZAMIL; BREFELDIN A; CYCLOHEXIMIDE; NYSTATIN; OUABAIN; POTASSIUM CHANNEL; POTASSIUM ION; SODIUM CHANNEL; SODIUM ION;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL MEMBRANE POTENTIAL; CELL MEMBRANE RESISTANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EPITHELIUM CELL; HYPERPOLARIZATION; KIDNEY EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; SODIUM TRANSPORT; TOAD;

EID: 0030022133     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1996.270.1.c138     Document Type: Article

References (30)

1. + permeability of tight epithelia. Noise analysis with amiloride and CGS 4270. J. Gen. Physiol. 85: 555-582, 1985.
2. Capparelli, A. W., M. C. Y. Heng, L. Li, O. D. Jo, and N. Yanagawa. Brefeldin A inhibits phosphate transport in opossum kidney cells. Am. J. Physiol. 264 (Cell Phvsiol. 33): C40-C47, 1993.
3. + transport in a model renal epithelial cell line. Biochim. Biophys. Acta 1190: 449-456, 1994.
4. Edleman, I. S. Receptors and effectors in hormone action on the kidney. Am. J. Physiol. 241 (Renal Fluid Electrolyte Physiol. 10): F333-F339, 1981.
5. Farquhar, M. G. Progress in unraveling pathways of Golgi traffic. Annu. Rev. Cell. Biol. 1: 447-488, 1985.
6. + transport with amiloride. Am. J. Physiol. 254 (Cell Physiol. 23): C297-C303, 1988.
7. -. J. Gen. Physiol. 97: 219-243, 1991.
8. Fishman, P. H., and P. K. Curran. Brefeldin A inhibits protein synthesis in cultured cells. FEBS Lett. 314: 371-374, 1992.
9. Fujiwara, T., K. Oda, S. Yokota, A. Takatsuki, and Y. Ikehara. Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum. J. Biol. Chem. 263:18545-18552, 1988.
10. 6 cells: effect of high sodium transport rate. Pfluegers Arch. 420: 559-565, 1992.
11. Griffiths, G., and K. Simons. The trans-Golgi network: sorting at the exit site of the Golgi complex. Science Wash. DC 234: 438-443, 1986.
12. + channels of frog skin J. Gen. Physiol. 95: 647-678, 1990.
13. + channel density and not open probability (Abstract). FASEB J. 8: A294, 1994.
14. Helman, S. I., W. Nagel, and R. S. Fisher. Ouabain on active transepithelial sodium transport in frog skin. Studies with microelectrodes. J. Gen. Physiol. 74: 105-127, 1979.
15. 6 epithelial cells (Abstract). J. Am. Soc. Nephrol. 3: 810, 1992.
16. 6 epithelia. Am. J. Physiol. 263 (Cell Physiol. 32): C825-C837, 1992.
17. 1 cells contain a nondiffusible, dominant factor that makes the Golgi apparatus resistant to brefeldin A. J. Cell Biol. 113: 1009-1023, 1991.
18. Lippincott-Schwartz, J., L. C. Yuan, J. S. Bonifacino, and R. D. Klausner. Rapid redistribution of Golgi proteins into the ER in the presence of brefeldin A suggests an ER recycling pathway. Cell 56: 801-813, 1989.
19. Lippincott-Schwartz, J., L. C. Yuan, C. Tipper, M. Amherdt, L. Orci, and R. D. Klausner. Brefeldin A's effects on endosomes, lysosomes, and TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell 67: 601-616, 1991.
20. + channels. Am. J. Physiol. 260 (Cell Physiol. 29): C1071-C1084, 1991.
21. + channels: function and diversity. Annu. Rev. Physiol. 54: 51-66, 1992.
22. Pelham, H. R. B. Multiple targets for brefeldin A. Cell 67: 449-451, 1991.
23. Rothman, J. E., and L. Orci. Movement of proteins through the Golgi stack: a molecular dissection of vesicular transport. FASEB J. 4: 1460-1468, 1990.
24. 6 Am. J. Physiol. 245 (Cell Physiol. 14): C167-C171, 1983.
25. Silver, R. B., G. Frindt, E. H. Windhager, and L. G. Palmer. Feedback regulation of Na channels in rat CCT. I. Effects of inhibition of Na pump. Am. J. Physiol. 264 (Renal Fluid Electrolyte Physiol. 33): F557-F564, 1993.
26. Turnheim, K. Intrinsic regulation of apical sodium entry in epithelia. Physiol. Rev. 71:429-445, 1991.
27. Van Driessche, W., and W. Zeiske. Ionic channels in epithelial cell membranes. Physiol. Rev. 65: 833-903, 1985.
28. Weng, K., and J. B. Wade. Effect of brefeldin A on ADH-induced transport responses of toad bladder. Am. J. Physiol. 266 (Cell Physiol. 35): C1069-C1076, 1994.
29. Wills, N. K. Antibiotics as tools for studying the electrical properties of tight epithelia. Federation Proc. 40: 2202-2205, 1981.
30. Zizi, M. A., R. S. Fisher, and F. G. Grillo. Formation of cation channels in planar lipid bilayers by brefeldin A. J. Biol. Chem. 266: 18443-18445, 1991.