Aging does not affect steady-state expression of the Na+/Ca2+ exchanger in rat brain

Cellular and Molecular Neurobiology

Volumn 16, Issue 1, 1996, Pages 11-19

  Colvin, Robert A ^a,b   Walker, Jon P ^a   Schummers, James ^c   Davis, Nancy ^a  

^a OHIO UNIVERSITY   (United States)

^b OHIO UNIVERSITY   (United States)

^c NONE

Author keywords

Ca2+ homeostasis; Ion transport; Northern analysis; Plasma membrane vesicles; Western analysis

Indexed keywords

CALCIUM ION; COMPLEMENTARY DNA; MEMBRANE PROTEIN; MESSENGER RNA; N ETHYLMALEIMIDE; POLYADENYLATED RNA; SODIUM ION;

ADOLESCENT; AGED; AGING; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CEREBELLUM; CONTROLLED STUDY; GENE EXPRESSION; HIPPOCAMPUS; MALE; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM CALCIUM EXCHANGE; STEADY STATE;

AGING; ANALYSIS OF VARIANCE; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, WESTERN; BRAIN; CALCIUM; CARRIER PROTEINS; CEREBELLUM; DNA PRIMERS; DNA PROBES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HIPPOCAMPUS; HUMANS; MALE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RATS; RATS, INBRED F344; RNA, MESSENGER; SODIUM; SODIUM-CALCIUM EXCHANGER; TRANSCRIPTION, GENETIC;

EID: 0030022118     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02578383     Document Type: Article

References (29)

1. Aceto, J. F., Condrescu, M., Kroupis, C., Nelson, H., Helson, N., Nicoll, D. Philipson, K. D., and Reeves, J. P. (1992). Cloning and expression of the bovine cardiac sodium-calcium exchanger. Arch. Biochem. Biophys. 298:533-560.
2. 2+ exchange activity and exchanger immunoreactivity in developing rabbit hearts. Am. J. Physiol. 263:H1506-H1513.
3. 2+ exchanger peak near birth in developing rabbit and rat hearts. Circ. Res. 74:354-359.
4. Bourdeau, J. E., Taylor, A. N., and Iacopino, A. M. (1993). Immunocytochemical localization of sodium-calcium exchanger in canine nephron. J. Am. Soc. Nephrol. 4:105-110.
5. 2+ exchange activity in human brain: the effect of normal aging. Neurobiol. Aging 14:373-381.
6. 2+ exchanger gene and their functional expression in HeLa cells. FEBS 319:105-109.
7. 2+ exchange by site-directed polyclonal antibodies. Biochim. Biophys. Acta 1160:293-300.
8. Khachaturian, Z. S. (1993). Calcium regulation-final common pathway for age-associated neurodegenerative processes. Neurosci. Res. Comm. 13:S3-S6.
9. Kieval, R. S., Bloch, R. J., Lindenmayer, G. E., Ambesi, A., and Lederer, W. J. (1992). Immunofluorescence localization of the Na-Ca exchanger in heart cells. Am. J. Physiol. 263:C545-C550.
10. Kofuji, P., Lederer, W. J., and Schulze, D. H. (1994). Mutually exclusive and cassette exons underlie alternatively spliced isoforms of the Na/Ca exchanger. J. Biol. Chein. 269:15145-15149.
11. 2+ exchanger cDNA. Proc. Natl. Acad. Sci. USA 89:4769-4773.
12. Laemmli, V. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
13. 2+ exchanger. J. Biol. Chem. 269:17434-17439.
14. 2+ exchanger and its functional expression in HeLa cells. FEBS 316:63-67.
15. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, A. J. (1951). Protein measurement with the Polin phenol reagent. J. Biol. Chem. 193:254-275.
16. Luther, P. W., Yip, R. K., Bloch, R. J., Ambesi, A., Lindenmayer, G. E., and Blausteim, M. P. (1992). Presynaptic localization of sodium/calcium exchangers in neuromuscular preparations. J. Neurosci. 12:4898-4904.
17. Marlier, L. N. J.-L., Zheng, T., Tang, J., and Grayson, D. R. (1993). Regional distribution in the rat central nervous system of a mRNA encoding a portion of the cardiac sodium/calcium exchanger isolated from cerebellar granule neurons. Mol. Brain Res. 20:21-39.
18. Martinez-Serrano, A., Blanco, P., and Satrustegui, J. (1992). Calcium binding to the cytosol and calcium extrusion mechanisms in intact synaptosomes and their alterations with aging. J. Biol. Chem. 267:4672-4679.
19. 2+ handling systems and neuronal aging. Ann. N.Y. Acad. Sci. 568:89-94.
20. 2+ regulation. Mech. Age. Dev. 25:215-225.
21. 2+ exchanger and tissue-specific expression of isoforms. J. Biochem. 114:528-534.
22. Ng, U. Y., Gunning, P., Eddy, R., Ponte, P., Leavitt, J., Shows, T., and Kedes, L. (1985). Evolution of the functional human α-actin gene and its multi-pseudogene family: Conservation of noncoding regions and chromosomal dispersion of pseudogenes. Mol. Cell. Biol. 5:2720-2732.
23. 2+ exchanger. Science 250:562-565.
24. Peterson, C. (1992). Changes in calcium's role as a messenger during aging in neuronal and nonneuronal cells. Ann. N.Y. Acad. Sci. 663:279-293.
25. Sambrook; J., Fritsch, E. F., and Maniatis, T. (1989). Molecular Cloning. A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
26. 2+ exchanger in end-stage human heart failure. Circ. Res. 75:443-453.
27. 2+ exchange in rat and human brain plasma membrane vesicles. J. Neiirochem. 63:2136-2143.
28. Yip, R. K., Blaustein, M. P., and Philipson, K. D. (1992). Immunologic identification of Na/Ca exchange protein in rat brain synaptic plasma membrane. Neurosci. Lett. 136:123-126.
29. 2+ exchanger by polymerase chain reaction. Am. J. Physiol. 263:F680-F685.