Effects of native and hydrolyzed whey protein on intestinal repair of severely starved rats at weaning

Journal of Pediatric Gastroenterology and Nutrition

Volumn 22, Issue 2, 1996, Pages 186-193

  Boza, Julio ^a   Jiménez, Jesús ^a   Baró, Luis ^b   Martínez, Olga ^b   Suárez, M Dolores ^a   Gil, Angel ^b  

^a UNIVERSITY OF GRANADA   (Spain)

^b Puleva Biotech SA   (Spain)

Author keywords

Enzymatic hydrolysates; Intestinal permeability; Rats; Starvation; Whey protein

Indexed keywords

ACETYLCHOLINESTERASE; ALPHA GLUCOSIDASE; BETA LACTOGLOBULIN; GLUTAMATE DEHYDROGENASE; OLIGO 1,6 GLUCOSIDASE; OVALBUMIN; PROTEIN HYDROLYSATE; SUCRASE;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; INTESTINE MUCOSA PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; STARVATION; WEANING; WHEY;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0030021859     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005176-199602000-00010     Document Type: Article

References (38)

1. Jambunathan LR, Neuhoff D, Younoszai MK. Intestinal disaccharidases in malnourished infant rats. Am J Clin Nutr 1981;34:1879-84.
2. Firmansyah A, Suwandito L, Penn D, Lebenthal E. Biochemical and morphological changes in the digestive tract of rats after prenatal and postnatal malnutrition. Am J Clin Nutr 1989;50:261-8.
3. Hatch TF. Effects of protein-calorie malnutrition on the digestive and absorptive capacities of infants. In: Lebenthal E, ed. Textbook of gastroenterology and nutrition in infancy. New York: Raven Press, 1989:767-77.
4. Heitlingher LA, Rossi TM, Lee P, Lebenthal E. Human intestinal disaccharidase activities: correlations with age, biopsy technique and degree of villus atrophy. J Pediatr Gastroenterol Nutr 1991;12:204-8.
5. Iyngkaran N, Yadav M, Boey CG. Intestinal brush border peptidases in cow's milk protein-sensitive enteropathy. Acta Paediatr Scand 1991;80:549-50.
6. Gruskay FL, Cooke RE. The gastrointestinal absorption of unaltered protein in normal infants recovering from diarrhoea. Pediatrics 1955;16:763-9.
7. Paganelli R, Atherton DJ, Levinsky RJ. Differences between normal and milk allergy subjects in their immune response after milk ingestion. Arch Dis Child 1983;58:201-6.
8. Husby S, Foged N, Host A, Svehag SE. Passage of dietary antigens into the blood of children with coeliac disease: quantification and size distribution of absorbed antigens. Gut 1987;28:1062-72.
9. Walker-Smith JA, Digeon B, Phillips AD. Evaluation of a casein and a whey hydrolysate for treatment of cow's-milk-sensitive enteropathy. Eur J Pediatr 1989;149:68-71.
10. Grimble GK, Keohane PP, Higgins BE, Kaminski MV, Silk DBA. Effect of peptide chain length on amino acid and nitrogen absorption from two lactoalbumin hydrolysates in the normal human jejunum. Clin Sci 1986;71:65-9.
11. Grimble GK, Rees RG, Keohane PP, Cartwright T, Desreumaux M, Silk DBA. Effect of peptide chain length on absorption egg protein hydrolysates in the normal human jejunum. Gastroenterology 1987;92:136-42.
12. Brinson RR, Hanumanthu SK, Pitts WM. A reappraisal of the peptide-based enterai formulas: clinical applications. Nutr Clin Pract 1989;4:211-7.
13. Rouanet JM, Zambonino Infante JL, Caporiccio B, Peojan C. Nutritional value and intestinal effects of dipeptides and tripeptides. Ann Nutr Metab 1990;34:175-82.
14. Poullain MG, Cezard JP, Roger L, Mendy F. Effect of whey proteins, their oligopeptide hydrolysates and free amino acid mixtures on growth and nitrogen retention in fed and starved rats. J Parenter Enter Nutr 1989;13:382-6.
15. Poullain MG, Cezard JP, Marche C, et al. Effect of dietary whey proteins, their peptides or amino-acids on the ileal mucosa of normally fed and starved rats. Clin Nutr 1991;10: 49-54.
16. Boza JJ, Jimenez J, Martinez O, Suarez MD, Gil A. Nutritional value and antigenicity of two milk protein hydrolysates in rats and guinea pigs. J Nutr 1994;124:78-86.
17. Knights R. Processing and evaluation on the antigenicity of protein hydrolysates. In: Lifishitz F, ed. Nutrition for special needs in infancy: protein hydrolysates. New York: Marcel Dekker, 1985:105-15.
18. Institute for Laboratory Animal Resources. Control of diets in laboratory animal experimentation. Nutr Abstr Rev 1979; 49:413-9.
19. National Research Council. Nutritional requirements of laboratory animals. Washington D.C.: National Academy of Sciences, 1978:7-30.
20. Association of Official Agricultural Chemists. Official methods of analysis. Arlington: AOAC, 1984:303-4.
21. Núñez MC, Ayudarte MV, Morales D, Suárez MD, Gil A. Effect of dietary nucleotides on intestinal repair in rats with experimental chronic diarrhea. J Parenter Enter Nutr 1990; 14:598-604.
22. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
23. Dahlquist A. Assay of intestinal disaccharidases. Anal Biochem 1968;22:99-107.
24. Goldstein R, Klein T, Freier S, Menczel J. Alkaline-phosphatase and disaccharidase activities in the rat intestine from birth to weaning: effect of diet on enzyme development. Am J Clin Nutr 1970;24:1224-31.
25. Maroux S, Louvard D, Baratti J. The aminopeptidase from hog intestinal brush-border. Biochim Biophys Acta 1973;321: 282-95.
26. Levine JB. Determination of acetylcholinesterase in blood with automated analysers. In: Bergmeyer HU, ed. Methods of enzymatic analysis. New York: Academic Press, 1974:860-4.
27. Schmidt E. Glutamate dehydrogenase UV-assay. In: Bergmeyer HU, ed. Methods of enzymatic analysis. New York: Academic Press, 1974:650-5.
28. Scholze T. Determination of phenylthiocarbamil amino acids by reversed-phase high-performance liquid chromatography. J Chromatograph 1985;350:453-60.
29. Morris ER, West J, Morgan JB, Hampton SM. Enzyme-linked immunosorbent assays for the gliadin and ovalbumin and their application in normal subjects. Eur J Clin Nutr 1993;47:673-7.
30. Husby S, Host A, Teisner B, Svehag SE. Infants and children with cow milk allergy/intolerance. Allergy 1990;45: 547-51.
31. Beyzavi K, Hampton SM, Kwasowski P, Fickling S, Marks V, Clift R. Comparison of horseradish peroxidase and alkaline phosphatase labelled antibodies in enzyme immunoassay. Ann Clin Biochem 1987;24:149-56.
32. Dixon WJ, Brown MB, Engelman L, Jennrich RI, eds. BMDP statistical software manual. Berkeley: University of California Press, 1990.
33. Rossouw JE, Pettifor JM. Protein-energy malnutrition. In: Cohen RD, Lewis B, Alberti KGMM, Denman AM, eds. The metabolic and molecular basis of acquired disease. London: Bailliére Tindall, 1990:514-30.
34. Worthington BS, Boatman ES, Kenny GE. Intestinal absorption of intact proteins in normal and protein-deficient rats. Am J Clin Nutr 1974;27:276-86.
35. Butzner JE, Gall DG. Impact of protein-calorie malnutrition on the developing intestine. Biol Neonate 1988;54:151-9.
36. Uhnoo I, Freihorst J, Riepenhoff-Talty M, Fisher JE, Ogra PL. Effect of rotavirus infection and malnutrition on uptake of a dietary antigen in the intestine. Pediatr Res 1990;27: 153-60.
37. Moughan PJ, Pedraza M, Smith WC, Williams M, Wilson MN. An evaluation with piglets of bovine milk, hydrolyzed bovine milk, and isolated soybean proteins included in infant milk formulas. I. Effect on organ development, digestive enzyme activities, and amino acid digestibility. J Pediatr Gastroenterol Nutr 1990;10:385-94.
38. Solomons NW, Molina S, Bulux J. Effect of protein-energy malnutrition on the digestive and absorptive capacities of infants and children. In: Lebenthal E, ed. Textbook of gastroenterology and nutrition in infancy. New York: Raven Press, 1989:517-33.