Stereospecific Grignard-activated solid phase synthesis of DNA methylphosphonate dimers

Journal of Organic Chemistry

Volumn 61, Issue 2, 1996, Pages 510-513

  Le Bec, Christine ^a,b   Wickstrom, Eric ^b  

^a INSTITUT PASTEUR   (France)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE;

ARTICLE; DNA SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; TECHNIQUE;

EID: 0030021274     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9517499     Document Type: Article

References (15)

1. Wickstrom, E., Ed. Prospects for Antisense Nucleic Acid Therapeutics for Cancer and AIDS; Wiley-Liss: New York, 1991.
2. Chang, E. H.; Miller, P. S. In Prospects for Antisense Nucleic Acid Therapeutics for Cancer and AIDS; Wickstrom, E., Ed.; Wiley-Liss: New York, 1991; pp 115-124.
3. Wickstrom, E. Trends Biotechnol. 1992, 10, 281-287.
4. Wickstrom, E.; Bacon, T. A.; Wiekstrom, E. L. Cancer Res. 1992, 62, 6741-6745.
5. Vyazovkina, E. V.; Savchenko, E. V.; Lokhov, S. G.; Engels, J. W.; Wickstrom, E.; Lebedev, A. V Nucleic Acids Res. 1994, 22, 2404-2409.
6. Wickstrom, E. In Gene Regulation: Biology of Antisense RNA and DNA; Erickson, R. P., Izant, J. G., Eds.; Raven Press; New York, 1992; pp 119-132.
7. Stec, W. J.; Lesmkowski, Z. J. In Methods in Molecular Biology, Vol. 20, Protocols for Oligonucleotides and Analogs, Synthesis and Properties; Agrawal, S., Ed.; Humana Press: Totowa NJ, 1993; pp 285-313.
8. Bonora, G. M.; Bianeotto, G.; Maffini, M.; Scremin, C. L. Nucleic Acids Res. 1993, 21, 1213-1217.
9. Le Bec, C.; Wickstrom, E. Tetrahedron Lett. 1994, 35, 9525-9528.
10. Wright, P.; Lloyd, D.; Rapp, W.; Andrus, A. Tetrahedron Lett. 1993, 34, 3373-3376.
11. Pieles, U.; Zurcher, W.; Schar, M ; Moser, H. E. Nucleic Acids Res. 1993, 21, 3191-3196.
12. Vyazovkina, E. V.; Engels, J. W.; Lebedev A. V. Bioorg. Khum. 1993, 19, 197-210.
13. Hogrefe, R. I.; Reynolds, M. A.; Vaghefi, M. M.; Young, K. M.; Riley, T. A.; Klem, R. E.; Arnold, L. J., Jr. In Methods in Molecular Biology. Vol. 20, Protocols for Oligonucleotides and Analogs, Synthesis and Properties; Agrawal, S., Ed., Humana Press: Totowa NJ, 1993; pp 143-164.
14. Stec, W. J.; Wilk, A. Angew. Chem., Int. Ed. Engl. 1994, 33, 709-722.
15. Sood, A.; Shaw, B. R.; Spielvogel, B. F. J. Am. Chem. Soc. 1990, 112, 9000-9001.