Postprandial lipemia: The origin of an early peak studied by specific dietary fatty acid intake during sequential meals

American Journal of Clinical Nutrition

Volumn 63, Issue 1, 1996, Pages 36-41

  Fielding, Barbara A ^b   Callow, Joanne ^b   Owen, Richard M ^b   Samra, Jaswinder S ^b   Matthews, David R ^b   Frayn, Keith N ^a  

^a RADCLIFFE INFIRMARY   (United Kingdom)

^b NONE

Author keywords

chylomicrons; dietary fatty acids; Humans; linoleic acid; nonesterified fatty acids; oleic acid; postprandial lipemia; triacylglycerol

Indexed keywords

CHYLOMICRON; FATTY ACID; LINOLEIC ACID; OLEIC ACID; TRIACYLGLYCEROL;

ADULT; ARTICLE; FAT INTAKE; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERLIPIDEMIA; LIPID METABOLISM; MALE; POSTPRANDIAL STATE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0030021154     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/63.1.36     Document Type: Article

References (28)

1. Patsch JR, Miesenböck G, Hopferwieser T, et al. Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state. Arterioscler Thromb 1992;12:1336-45.
2. Cohn JS, McNamara JR, Cohn SD, Ordovas JM, Schaefer EJ. Postprandial plasma lipoprotein changes in human subjects of different ages. J Lipid Res 1988,29:469-79.
3. Cohn JS, McNamara JR, Krasinski SD, Russell RM, Schaefer EJ Role of triglyceride-rich lipoproteins from the liver and intestine in the etiology of postprandial peaks in plasma triglyceride concentration. Metabolism 1989;38:484-90.
4. Heller FR, Vandenplas C, Desager JP, Harvengt C. The vitamin A fat-loading test in young normolipidemic subjects. Clin Chim Acta 1993;219:167-76.
5. Olefsky JM, Crapo P, Reaven GM. Postprandial plasma triglyceride and cholesterol responses to a low-fat meal. Am J Clin Nutr 1976;29: 535-9.
6. Williams CM, Moore F. Morgan L, Wright J. Effects of n - 3 fatty acids on postprandial triacylglycerol and hormone concentrations in normal subjects. Br J Nutr 1992;68:655-66.
7. Peel AS, Zampelas A, Williams CM, Gould BJ. A novel antiserum specific to apolipoprotein B-48: application in the investigation of postprandial lipidaemia in humans. Clin Sci 1993;85:521-4.
8. Coppack SW, Frayn KN, Humphreys SM. Plasma triacylglycerol extraction in human adipose tissue in vivo: effects of glucose ingestion and insulin infusion. Eur J Clin Nutr 1989;43:493-6.
9. Frayn KN, Shadid S, Hamlani R, et al. Regulation of fatty acid movement in human adipose tissue in the postabsorptive to postprandial transition. Am J Physiol 1994;266:E308-17.
10. Callow J, Owen R, Fielding BA, Samra JS, Frayn KN. Regulation of the plasma non-esterified fatty acid concentration after meals. Proc Nutr Soc 1995,54:52A(abstr).
11. Fielding BA, Owen R, Callow J, Frayn KN. Origin of the early postprandial triacylglycerol peak. Proc Nutr Soc 1995;54:53A(abstr).
12. Fielding BA, Callow J, Owen R, Samra JS, Frayn KN. The origin of plasma non-esterified fatty acids in the post-prandial period. Proc Nutr Soc (in press).
13. Holland BA, Welch AA, Unwin ID, Buss DH, Paul AA, Southgate DAT. McCance and Widdowson's the composition of foods. 5th ed. Cambridge, United Kingdom: Royal Society of Chemistry and Ministry of Agriculture, Fisheries and Food. 1991.
14. Griffiths JA, Humphreys SM, Clark ML, Fielding BA, Frayn KN. Immediate metabolic availability of dietary fat in combination with carbohydrate. Am J Clin Nutr 1994;59:53-9.
15. Humphreys SM, Fisher RM, Frayn KN. Micro-method for measurement of sub-nanomole amounts of triacylglycerol. Ann Clin Biochem 1990;27:597-8.
16. Clark ML, Humphreys SM, Frayn KN. Stability of plasma glucose during storage. Ann Clin Biochem 1990;27:373-7.
17. Matthews DR. Times series analysis in endocrinology. Acta Paediatr Scand Suppl 1988;347:55-62.
18. Cohn JS, Johnson EJ, Millar JS, et al. Contribution of apoB-48 and apoB-100 triglyceride-rich lipoproteins (TRL) to postprandial increases in the plasma concentration of TRL triglycerides and retinyl esters. J Lipid Res 1993;34.2033-40.
19. Coppack SW, Fisher RM, Gibbons GF, et al. Postprandial substrate deposition in human forearm and adipose tissues in vivo. Clin Sci 1990;79:339-48.
20. Reaven GM, Hollenbeck C, Jeng C-Y, Wu MS, Chen Y-DI. Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM. Diabetes 1988;37:1020-4.
21. Halliwell K, Samra JS, Clark ML, Fielding BA, Humphreys SM, Frayn KN. Release of individual fatty acids from human subcutaneous adipose tissue in vivo. Int J Obes 1995;19(suppl 2):71.
22. Scow RO Metabolism of chylomicrons in perfused adipose and mam-mary tissue of the rat. Fed Proc 1977;36:182-5.
23. Bergman EN, Havel RJ, Wolfe BM, Bohmer T. Quantitative studies of the metabolism of chylomicron triglycerides and cholesterol by liver and extrahepatic tissues of sheep and dogs. J Clin Invest 1971;50: 1831-9.
24. Heimberg M, Dunn GD, Wilcox HG. The derivation of plasma-free fatty acids from dietary neutral fat in man. J Lab Clin Med 1974;83: 393-402.
25. Roust LR, Jensen MD. Postprandial free fatty acid kinetics are abnormal in upper body obesity. Diabetes 1993;42:1567-73.
26. Cianflone K, Vu H, Walsh M, Baldo A, Smderman A. Metabolic response of acylation stimulating protein to an oral fat load. J Lipid Res 1989;30:1727-33.
27. Oliver MF, Opie LH. Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias. Lancet 1994;343:155-8.
28. Hoak JC. What is the historical background of research on the role of fatty acids in thrombosis? Am J Clin Nutr 1992;56(suppl):786S.