Influence of skin temperature on heat pain threshold in humans

Experimental Brain Research

Volumn 107, Issue 3, 1996, Pages 497-503

  Pertovaara, Antti ^a,b   Kauppila, Timo ^b   Hämäläinen, Minna M ^b  

^a UNIVERSITY OF TURKU   (Finland)

^b Department of Physiology ^*  (Finland)

Author keywords

Adapting skin temperature; Heat pain threshold; Human; Mechanical pain threshold; Rate of stimulus rise; Temporal summation

Indexed keywords

ADULT; ARTICLE; FOREARM; GLABROUS SKIN; HAND; HEAT; HUMAN; HUMAN EXPERIMENT; LATENT PERIOD; NOCICEPTION; PAIN THRESHOLD; PRIORITY JOURNAL; SKIN TEMPERATURE; TEMPORAL SUMMATION;

EID: 0030021138     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00230429     Document Type: Article

References (40)

1. Adriaensen HJ, Gybels J, Handwerker HO, VanHees J (1983) Response properties of thin myelinated (A-δ) fibres in human skin nerves. J Neurophysiol 49: 111-122
2. Adriaensen HJ, Gybels J, Handwerker HO, VanHees J (1984) Suppression of C-fibre discharges upon repeated heat stimulation may explain characteristics of concomitant pain sensations. Brain Res 302: 203-211
3. Arendt-Nielsen L, Bjerring P (1988) Sensory and pain threshold characteristics to laser stimuli. J Neurol Neurosurg Psychiatry 51: 35-42
4. Benjamin FB (1959) Spatial summation of pain. Proc Soc Exp Biol Med 101: 380-382
5. Berge OG, Garcia-Cabrera I, Hole K (1988) Response latencies in the tail-flick test depend on tail skin temperature. Neurosci Lett 86: 284-288
6. Birren JE, Casperson RC, Botwinick J (1951) Pain measurement by the radiant heat method: individual differences in pain sensitivity, the effects of skin temperature, and stimulus duration. J Exp Psychol 41: 419-424
7. 2 laser stimuli causing pain. Exp Brain Res 55: 158-166
8. Campbell JN, LaMotte RH (1983) Latency to detection of first pain. Brain Res 266: 203-208
9. Casey KL, Butler J, Lewis KG, Morrow TJ (1987) Evidence that the distribution of polymodal nociceptors does not determine both thermal and mechanical pain thresholds of human glabrous and hairy skin. Soc Neurosci Abstr 13: 189
10. Croze S, Duclaux R (1978) Thermal pain in humans: influence of the rate of stimulation. Brain Res 157: 418-421
11. Croze S, Duclaux R, Kenshalo DR (1976) The thermal sensitivity of the polymodal nociceptors in the monkey. J Physiol (Lond) 263: 539-562
12. Croze S, Duclaux R, Russek M (1977) Constancy of heat pain characteristics to changes in skin and body temperature. Brain Res 131: 367-372
13. Douglass DK, Carstens E, Watkins LR (1992) Spatial summation in human thermal pain perception: comparison with and between dermatomes. Pain 50: 197-202
14. Duggan AW, Griersmith BT, Headley PM, Maher JB (1978) The need to control skin temperature when using radiant heat in tests of analgesia. Exp Neurol 61: 471-478
15. Greene LC, Hardy JD (1958) Spatial summation of pain. J Appl Physiol 13: 457-464
16. Hall KR (1955) Relation of skin temperature to pain threshold. Q J Exp Psychol 7: 74-81
17. Hallin RG, Torebjörk HE, Wiesenfeld Z (1981) Nociceptors and warm receptors innervated by C fibres in human skin. J Neurol Neurosurg Psychiatry 45: 313-319
18. Hardy JD, Goodell H, Wolff HG (1951) The influence of skin temperature upon the pain threshold as evoked by thermal radiation. Science 114: 149-150
19. Hardy JD, Wolff HG, Goodell H (1952) Pain sensations and reactions. Williams & Wilkins, Baltimore
20. Hole K, Tjolsen A (1993) The tail-flick and formalin tests in rodents: changes in skin temperature as a confounding factor. Pain 53: 247-254
21. Kojo I, Pertovaara A (1986) Effect of tourniquet-induced ischemia on cutaneous thermal thresholds. Acta Neurol Scand 74: 383-386
22. Kojo I, Pertovaara A (1987) The effects of stimulus area and adaptation temperature on warm and heat pain thresholds in man. Int J Neurosci 32: 875-880
23. Lichtman AH, Smith FL, Martin BR (1993) Evidence that the antinociceptive tail-flick response is produced independently from changes in either tail-skin temperature or core temperature. Pain 55: 283-295
24. Luukko M, Konttinen Y, Kemppinen P, Pertovaara A (1994) Influence of various experimental parameters on the incidence of thermal and mechanical hyperalgesia induced by a constriction mononeuropathy of the sciatic nerve in lightly anesthetized rat. Exp Neurol 128: 143-154
25. Lynn B (1979) The heat sensitization of polymodal nociceptors in the rabbit and its independence of the local blood flow. J Physiol (Lond) 287: 493-507
26. Machet-Pietropaoli H, Chery-Croze S (1979) Spatial summation of thermal pain in human beings. Sensory Process 3: 183-187
27. Mendell LM (1966) Physiological properties of unmyelinated fibre projections to the spinal cord. Exp Neurol 16: 316-332
28. Milne RJ, Gamble GD (1989) Habituation to sham testing procedures modifies tail-flick latencies: effects on nociception rather than vasomotor tone. Pain 39: 103-107
29. Pertovaara A, Kojo I (1985) Influence of the rate of temperature change on thermal thresholds in man. Exp Neurol 87: 439-445
30. Pertovaara A, Reinikainen K, Hari R (1984) The activation of unmyelinated or myelinated afferent fibers by brief infrared laser pulses varies with skin type. Brain Res 307: 341-343
31. 2 laser pulses in humans: evidence on afferent mechanisms and the influence of varying stimulus conditions. Pain 34: 261-269
32. Price DD, Hu JW, Dubner R, Gracely RH (1977) Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses. Pain 3: 57-68
33. Price DD, McHaffie JG, Larson MA (1989) Spatial summation of heat-induced pain: influence of stimulus area and spatial separation of stimuli on perceived sensation intensity and unpleasentness. J Neurophysiol 62: 1270-1279
34. Torebjörk HE, LaMotte RH, Robinson CJ (1984) Peripheral neural correlates of magnitude of cutaneous pain and hyperalgesia: simultaneous recordings in humans of sensory judgments of pain and evoked responses in nociceptors with C-fibres. J Neurophysiol 51: 325-339
35. Treede RD, Oakland DB, Meyer RA, Campbell JN (1990) The apparent heat threshold of C-fiber nociceptors is dependent on stimulus parameters. Soc Neurosci Abstr 16-416
36. VanHees J, Gybels J (1981) C nociceptor activity in human nerve during painful and non-painful skin stimulation. J Neurol Neurosurg Psychiatry 44: 600-607
37. Wilcox GL, Giesler GL (1984) An instrument using a multiple layer Peltier device to change skin temperature rapidly. Brain Res Bull 12: 143-146
38. Yarnitsky D, Ochoa JL (1990) Studies of heat pain sensation in man: perception thresholds, rate of stimulus rise and reaction time. Pain 40: 85-91
39. Yarnitsky D, Ochoa JL (1991) Differential effect of compression-ischaemia block on warm sensation and heat-induced pain. Brain 114: 907-913
40. Yarnitsky D, Simone DA, Dotson RM, Cline MA, Ochoa JL (1992) Single C nociceptor responses and psychophysical parameters of evoked pain: effect of rate of rise of heat stimuli in humans. J Physiol (Lond) 450: 581-592