Autocrine induction of DNA synthesis by mechanical injury of cultured smooth muscle cells: Potential role of FGF and PDGF

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 16, Issue 2, 1996, Pages 187-193

  Calara, Federico ^a   Ameli, Sean ^a   Hultgårdh Nilsson, Anna ^b   Cercek, Bojan ^a   Kupfer, Joel ^a   Hedin, Ulf ^c   Forrester, James ^a   Shah, Prediman K ^a   Nilsson, Jan ^c  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

antisense; growth factors; injury; smooth muscle cells

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DNA; FIBROBLAST GROWTH FACTOR; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR AA;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; MUSCLE GROWTH; MUSCLE INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 0030020902     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.16.2.187     Document Type: Article

References (32)

1. Clowes AW, Reidy MA, Clowes MM. Mechanisms of stenosis after arterial injury. Lab Invest. 1983;49:208-215.
2. Ross R, Raines EW, Bowen-Pope DF. The biology of platelet- derived growth factor. Cell. 1986;46:155-169.
3. Klagsbrun M, Edelman ER. Biological and biochemical properties of fibroblast growth factors: implications for the pathogenesis of atherosclerosis. Arteriosclerosis. 1989;9:269-278.
4. Gospadorowicz D, Hirabayashi K, Giguere L, Tauber JP. Factors controlling the proliferative rate, final cell density, and life span of bovine vascular smooth muscle cells in culture. J Cell Biol. 1981;89: 568-578.
5. Pfeifle B, Boeder H, Ditschuneit H. Interaction of receptors for insulin like growth factor I, platelet derived growth factor and fibroblast growth factor in rat aortic cells. Endocrinology. 1987;120: 2251-2258.
6. Nilsson J, von Euler AM, Dalsgaard C-J. Stimulation of connective tissue cell growth by the neuropeptides substance P and substance K. Nature. 1985;315:61-63.
7. Nilsson J, Sjölund M, Palmberg L, Thyberg J, Heldin C-H. Arterial smooth muscle cells in primary culture produce a platelet-derived growth factor-like protein. Proc Natl Acad Sci U S A. 1985;82: 4418-4422.
8. Olson N, Chao S, Lindner V, Reidy M. Intimal smooth muscle cell proliferation after balloon catheter injury. Am J Pathol. 1992;140: 1017-1023.
9. Clemmons DR. Variables controlling the secretion of a somatomedin-like peptide by cultured porcine smooth muscle cells. Circ Res. 1985;56:418-442.
10. Naftilan AJ, Pratt RE, Dzau VJ. Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells. J Clin Invest. 1989;83: 1419-1424.
11. Raines E, Dower S, Ross R. Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA. Science. 1989;243:393-396.
12. Battegay E, Raines E, Seifert R, Bowen-Pope D, Ross R. TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell. 1990;63:515-524.
13. Reidy MA, Silver M. Endothelial regeneration, VII: lack of intimal proliferation after defined injury to rat aorta. Am J Pathol. 1985; 118:173-177.
14. Majesky MW, Reidy MA, Bowen-Pope DF, Hart CE, Wilcox JN, Schwartz SM. PDGF ligand and receptor gene expression during repair of arterial injury. J Cell Biol. 1990;111:2149-2158.
15. Jawien A, Bowen-Pope DF, Lindner V, Schwartz SM, Clowes AW. Platelet-derived growth factor promotes smooth muscle cell migration and intimal thickening in a rat model of balloon angioplasty. J Clin Invest. 1990;89:507-511.
16. Ferns GA, Raines EW, Sprugel KH, Motani AS, Reidy MA, Ross R. Inhibition of neointimal smooth muscle cell accumulation after angioplasty by an antibody to PDGF. Science. 1991;253:1129-1132.
17. Lindner V, Reidy M. Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. Proc Natl Acad Sci U S A. 1991;88:3739-3743.
18. Jackson CL, Reidy MA. Basic fibroblast growth factor: its role in the control of smooth muscle cell migration. Am J Pathol. 1993;143: 1024-1031.
19. Nilsson J, Ksiazek T, Heldin C-H, Thyberg J. Demonstration of stimulatory effects of platelet-derived growth factor on arterial smooth muscle cells: difference between cells from young and adult animals. Exp Cell Res. 1983;145:231-237.
20. Collins T, Bonthron DT, Orkin SH. Alternative RNA splicing affects function of encoded platelet-derived growth factor A chain. Nature. 1987;328:621-624.
21. Flugelman MY, Virmani R, Correa R, Yu ZX, Farb A, Leon MB, Elami A, Fu YM, Casscells W, Epstein SE. Smooth muscle cell abundance and fibroblast growth factors in coronary lesions of patients with nonfatal unstable angina. Circulation. 1993;88: 493-500.
22. Walker LN, Bowen-Pope DF, Ross R, Reidy MA. Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injury. Proc Natl Acad Sci U S A. 1986;83:7311-7315.
23. Bywater M, Rorsman F, Bongcam-Rudloff E, Mark G, Hammacher A, Heldin C-H, Westermark B, Betsholtz C. Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in Rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects. Mol Cell Biol. 1988;8:2753-2762.
24. Behl C, Bogdahn U, Winkler J, Apfel R, Brysch W, Schlingensiepen K-H. Autoinduction of platelet derived growth factor (PDGF) A-chain mRNA expression in a human malignant cell line and growth inhibitory effects of PDGF A-chain mRNA-specific antisense molecules. Biochem Biophys Res Commun. 1993;193: 744-751.
25. Seifert RA, Schwartz SM, Bowen-Pope DF. Developmentally regulated production of platelet-derived growth factor-like molecules. Nature. 1984;311:669-671.
26. Wilson E, Mai Q, Sudhir K, Weiss RH, Ives HE. Mechanical strain induces growth of vascular smooth muscle cells via autocrine action of PDGF. J Cell Biol. 1993;123:741-747.
27. Stiko-Rahm A, Hultgårdh-Nilsson A, Regnström J, Hamsten A, Nilsson J. Oxidized and native LDL enhance production of PDGF AA and the surface expression of PDGF receptors in cultured human arterial smooth muscle cells. Arterioscler Thromb. 1992;12: 1099-1199.
28. Inui H, Kitami Y, Tani M, Kondo T, Inagami T. Differences in signal transduction between platelet-derived growth factor (PDGF) α and β receptors in vascular smooth muscle cells. J Biol Chem. 1994;269:30546-30552.
29. Hultgårdh-Nilsson A, Krondahl U, Querol-Ferrer V, Ringertz NR. Differences in growth factor response in smooth muscle cells isolated from adult and neonatal rats. Differentiation. 1991;47:99-105.
30. Simons M, Edelman ER, DeKeyser JL, Langer R, Rosenberg RD. Antisense c-myb oligonucleotides inhibit arterial smooth muscle cell accumulation in vivo. Nature. 1992;359:67-70.
31. Biro S, Fu YM, Yu ZX, Epstein SE. Inhibitory effects of antisense oligodeoxynucleotides targeting c-myc mRNA on smooth muscle cell proliferation and migration. Proc Natl Acad Sci U S A. 1993;90: 654-658.
32. Burgess TL, Fisher EF, Ross SL, Bready JV, Qian YX, Bayewitch LA, Chen AM, Herrera CJ, Hu S, Kramer TB, Lott FD, Martin FH, Pierce GP, Simonet L, Farrell CL. The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism. Proc Natl Acad Sci U S A. 1995;92:4051-4055.