The conformation of human big endothelin-1 favours endopeptidase hydrolysis of the TRP21-VAL22 bond

Biochemical Pharmacology

Volumn 51, Issue 3, 1996, Pages 259-266

  Corder, Roger ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Blood pressure; Endothelin converting enzyme; Endothelium; Vascular smooth muscle; Vasoconstriction

Indexed keywords

BIG ENDOTHELIN 1; ENDOTHELIN 1; ENDOTHELIN CONVERTING ENZYME; PHLORETIC ACID N HYDROXYSUCCINIMIDE ESTER; PROTEIN DERIVATIVE; PROTEINASE; S ACETYLTHIOGLYCOLIC ACID N HYDROXYSUCCINIMIDE ESTER; SUCCINIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTERY CONSTRICTION; ARTICLE; CATTLE; CELL CULTURE; CONTROLLED STUDY; DERIVATIZATION; ENDOTHELIUM CELL; HYDROLYSIS; MALE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MODIFICATION; PROTEIN SECONDARY STRUCTURE; RADIOIMMUNOASSAY; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; BLOOD PRESSURE; CELLS, CULTURED; ENDOPEPTIDASES; ENDOTHELIN-1; ENDOTHELINS; ENDOTHELIUM, VASCULAR; HUMANS; HYDROLYSIS; MALE; MUSCLE, SMOOTH, VASCULAR; PROTEIN CONFORMATION; PROTEIN PRECURSORS; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; TRYPTOPHAN; VALINE; VASOCONSTRICTOR AGENTS;

EID: 0030020655     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02164-7     Document Type: Article

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