Characterization of an insulin from the three-toed amphiuma (Amphibia: Urodela) with an N-terminally extended A-chain and high receptor-binding affinity

Biochemical Journal

Volumn 313, Issue 1, 1996, Pages 283-287

  Conlon, J Michael ^a   Cavanaugh, Elizabeth S ^a   Mynarcik, Dennis C ^b   Whittaker, Jonathan ^b  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR; IODINE 125; PIG INSULIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; DNA TRANSFECTION; FEMALE; HORMONE RECEPTOR INTERACTION; HORMONE STRUCTURE; MALE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; RADIOASSAY; RECEPTOR AFFINITY; SALAMANDER; STRUCTURE ACTIVITY RELATION;

ADENOVIRIDAE; AMPHIBIA; AMPHIUMA; AMPHIUMA MEANS; AMPHIUMA TRIDACTYLUM; ANIMALIA; CAUDATA; GALLUS GALLUS; SUIDAE; SUS SCROFA;

EID: 0030020412     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3130283     Document Type: Article

References (31)

1. Carroll, R. L. (1988) Vertebrate Paleontology and Evolution, pp. 180-191, W. H. Freeman, New York
2. Andersen, A. C., Tonon, M. C., Pelletier, G., Conlon, J. M., Fasolo, A. and Vaudry, H. (1992) Int. Rev. Cytol. 138, 89-210
3. Hedges, S. B., Moberg, K. D. and Maxson, L. R. (1990) Mol. Biol. Evol. 7, 607-633
4. Shulinder, A. R., Bennett, C., Robinson, E. A. and Roth, J. (1989) Endocrinology 125, 469-477
5. Conlon, J. M., Hilscher-Conklin, C. and Boyd, S. (1995) Peptides, in the press
6. Conlon, J. M. and Hicks, J. W. (1990) Peptides 11, 461-466
7. Bailey, C. J. and Ahmed-Sorour, H. (1980) Diabetelogia 19, 475-481
8. Williams, P. F., Mynarcik, D. C., Yu, G. Q. and Whittaker, J. (1995) J. Biol. Chem. 270, 3012-3016
9. Baker, E. N., Blundell, T. L., Cutfield, J. F., Cutfield, S. M., Dodson, E. J., Dodson, G. G., Hodgkin, D. M. C., Hubbard, R. E., Isacs, N. W., Reynolds, C. D., Sakabe, K., Sakabe, N. and Vijayan, N. M. (1988) Philos. Trans. R. Soc. London Ser. B 319, 369-456
10. Hedges, S. B., Nussbaum, R. A. and Maxson, L. R. (1993) Herpetol. Monogr. 7, 64-76
11. Van der Horst, G. J., Visser, G. J. and Van der Merwe, L. (1991) J. Herpetol. 25, 441-447
12. Bajaj, M., Blundell, T. and Wood, S. (1984) in Molecular Variants of Proteins - Biosynthesis and Clinical Relevance (Campbell, P. N. and Phelps, C., eds.), pp. 45-54, Biochemical Society, London
13. Plisetskaya, E. M., Pollock, H. G., Elliott, W. M., Youson, J. H. and Andrews, P. C. (1988) Gen. Comp. Endocrinol. 69, 46-55
14. Conlon, J. M., Bondereva, V., Rusakov, Y., Plisetskaya, E., Mynarcik, D. C. and Whittaker, J. (1995) Gen. Comp. Endocrinol. 100, 96-105
15. Steiner, D. F., Smeekins, S. P., Ohagi, S. and Chan, S. J. (1992) J. Biol. Chem. 267, 23435-23438
16. Smeekens, S. P., Montag, A. G., Thomas, G., Albiges-Rizo, C., Carrol, R., Benig, M., Phillips, L. A., Martin, S., Ohagi, S., Gardner, P., Swift, H. H. and Steiner, D. F. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 8822-8826
17. Lomedico, P., Rosenthal, N., Efstratiadis, A., Gilbert, W., Kolodner, R. and Tizard, R. (1979) Cell 18, 545-558
18. Perler, F., Efstratiadis, A., Lomedico, P., Gilbert, W. Kolodner, R. and Dodgson, J. (1980) Cell 20, 555-566
19. Shulinder, A. R., Phillips, S., Roberts, C. T., LeRoith, D. and Roth, J. (1989) J. Biol. Chem. 264, 9428-9432
20. Chan, S. J., Emdin, S. O., Kwok, S. C. M., Kramer, J. M., Falkmer, S. and Steiner, D. F. (1981) J. Biol. Chem. 256, 7595-7602
21. Lipkind, G., Gong, Q. and Steiner, D. F. (1995) J. Biol. Chem. 270, 13277-13284
22. Conlon, J. M., Goke, R., Andrews, P. C. and Thim, L. (1989) Gen. Comp. Endocrinol. 73, 136-146
23. Simon, J., Freychet, P., Rosselin, G. and DeMeyts, P. (1977) Endocrinology 100, 115-121
24. Gammeltoft, S. (1984) Physiol. Rev. 64, 1321-1378
25. Plisetskaya, E. M., Pollock, H. G., Rouse, J. B., Hamilton, J. W., Kimmel, J. R. and Gorbman, A. (1985) Regul. Pept. 11, 105-116
26. Katsoyannis, P. G., Zalut, C., Harris, A. and Meyer, R. J. (1971) Biochemistry 10, 3884-3889
27. Gliemann, J. and Gammelton, S. (1975) Diabetelogia 10, 105-113
28. Markussen, J., Hougaard, P., Ribel, U., Sorensen, A. R. and Sorensen, E. (1987) Protein Eng. 1, 205-213
29. Schaffer, L. (1994) Eur. J. Biochem. 221, 1127-1132
30. Waelbroeck, M. (1982) J. Biol. Chem. 257, 8284-8291
31. Rosen, P., Simon, M., Reinauer, H., Friesen, H. J., Diaconescu, C. and Brandenburg, D. (1980) Biochem. J. 186, 945-952