Three novel rearranged cholestane glycosides from Ornithogalum saundersiae bulbs and their cytostatic activities on leukemia HL-60 and MOLT-4 cells

Tetrahedron Letters

Volumn 37, Issue 8, 1996, Pages 1245-1248

  Mimaki, Yoshihiro ^a   Kuroda, Minpei ^a   Sashida, Yutaka ^a   Hirano, Toshihiko ^a   Oka, Kitaro ^a   Dobashi, Akira ^a   Koshino, Hiroyuki ^b   Uzawa, Jun ^b  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTANE DERIVATIVE; DOXORUBICIN; ETOPOSIDE; GLYCOSIDE; METHOTREXATE; VINCRISTINE;

ARTICLE; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; INFRARED SPECTROPHOTOMETRY; LEUKEMIA CELL; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; PHYTOCHEMISTRY; PLANT;

EID: 0030020374     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(95)02407-7     Document Type: Article

References (7)

1. The monosaccharides were identified by converting them to the 1-[(S)-N-acetyl-α-methylbenzylamino]-1-deoxyalditol acetate derivatives followed by HPLC analysis. Oshima, R.; Yamauchi, Y.; Kumanotani, J. Carbohydr. Res. 1982, 107, 169-176.
2. Fäcke, T.; Berger, S. J. Magn. Reson. Ser. A 1995, 113, 257-259.
3. Agrawal, P. K.; Jain, D. C.; Gupta, R. K.; Thakur, R. S. Phytochemistry 1985, 24, 2479-2496; Agrawal, P. K. Phytochemistry 1992, 31, 3307-3330.
4. Agrawal, P. K.; Jain, D. C.; Gupta, R. K.; Thakur, R. S. Phytochemistry 1985, 24, 2479-2496; Agrawal, P. K. Phytochemistry 1992, 31, 3307-3330.
5. Haasnoot, C. A. G.; Leeuw, F. A. A. M. De; Altona C. Tetrahedron 1980, 36, 2783-2792.
6. DNA fragmentation has been known as a characteristic feature of apoptosis. Wyllie, A. H.; Kerr, J. F.; Currie, A. R. Int. Rev. Cytol., 1980, 68, 251-306.
7. 2+ inhibits the enzyme activities which results in blocks of apoptosis. Duke, R. C.; Chervenak, R.; Cohen, J. J. Proc. Natl. Acad. Sci. 1983, 80, 6361-6365.