Quantification of the extent of attenuation of the rate of turnover chemistry of the TEM-1 β-lactamase by the α-1R-hydroxyethyl group in substrates

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 3, 1996, Pages 319-322

  Miyashita, Kazuyuki ^a   Massova, Irina ^a   Mobashery, Shahriar ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6ALPHA (1 HYDROXYETHYL)PENICILLANIC ACID; 6BETA (1 HYDROXYETHYL)PENICILLANIC ACID; BETA LACTAMASE; CARBAPENEM DERIVATIVE; IMIPENEM; PENICILLIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STABILITY; DRUG SYNTHESIS; ENZYME BINDING; MOLECULAR DYNAMICS; STRUCTURE ACTIVITY RELATION;

EID: 0030020367     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00022-4     Document Type: Article

References (7)

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5. Miyashita, K.; Massova, I.; Taibi, P.; Mobashery, S. J. Am. Chem. Soc. 1995, 117, 11055.
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7. Imtiaz, U.; Billings, E. M.; Knox, J. R.; Mobashery, S. Biochemistry 1994, 33, 5728.