Expression of the nucleoside triphosphate pyrophosphohydrolase PC-1 is induced by basic fibroblast growth factor (bFGF) and modulated by activation of the protein kinase A and C pathways in osteoblast-like osteosarcoma cells

Journal of Bone and Mineral Research

Volumn 11, Issue 2, 1996, Pages 183-192

  Solan, Joell L ^a   Deftos, Leonard J ^a   Goding, James W ^b   Terkeltaub, Robert A ^a,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b MONASH UNIVERSITY MEDICAL SCHOOL   (Australia)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 8 BROMO CYCLIC AMP; ALKALINE PHOSPHATASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOKINE; INORGANIC PYROPHOSPHATASE; MESSENGER RNA; MONOCLONAL ANTIBODY; NUCLEOSIDE TRIPHOSPHATE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHODIESTERASE I; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RECOMBINANT ACIDIC FIBROBLAST GROWTH FACTOR; RECOMBINANT BASIC FIBROBLAST GROWTH FACTOR; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT SOMATOMEDIN C; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; STAUROSPORINE;

ARTICLE; BONE METABOLISM; BONE MINERALIZATION; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MULTIGENE FAMILY; OSTEOBLAST; OSTEOSARCOMA CELL; SIGNAL TRANSDUCTION;

CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; HUMANS; OSTEOBLASTS; OSTEOSARCOMA; PROTEIN KINASE C; PYROPHOSPHATASES; TUMOR CELLS, CULTURED;

EID: 0030020239     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.5650110207     Document Type: Article

References (57)

1. Zheng MH, Wood DJ, Papadimitriou JM 1992 What's new in the role of cytokines on osteoblast proliferation and differentiation? Path Res Pract 188:1104-1121.
2. Ali SY 1992 Matrix formation and mineralisation in bone. In: Whitehead CC (ed.) Bone Biology and Skeletal Disorders. Carfax, Abingdon, U.K., pp. 19-38.
3. Raisz LG 1993 Bone cell biology: new approaches and unanswered questions. J Bone Miner Res 8(Suppl 2)S457-S465.
4. Anderson HC 1988. Mechanisms of pathologic calcification. Rheum Dis Clin N Am 14:303-319.
5. Fedde KN 1992 Human osteosarcoma cells spontaneously release matrix-vesicle-like structures with the capacity to mineralize. Bone Miner 17:145-151.
6. 3 and transforming growth factor β(TGFβ). Bone Miner 17:139-144.
7. Ringbom-Anderson T, Jantti J, Akerman KEO 1994 Production and release of matrix vesicles in the cell processes of TPA-treated human osteoblast-like cells. J Bone Miner Res 9:661-670.
8. 3, parathyroid hormone, and dexamethasone. J Bone Miner Res 9:1259-1266.
9. de Jong ASH, Hak JJ, van Dujin P 1980 The dynamics of calcium phosphate precipitation studied with a new polyacrylamide steady state matrix model: Influence of pyrophosphate, collagen and chondroitin sulphate. Connect Tissue Res 7:73-79.
10. Siegel SA, Hummel CF, Carty RP 1983 The role of NTP pyrophosphohydrolase in in vitro NTP-dependent matrix vesicle calcification. J Biol Chem 258:8601-8607.
11. Meyer JL 1984 Can biological calcification occur in the presence of pyrophosphate? Arch Biochem Biophys 231:1-8.
12. Fleisch H 1994 The use of bisphosphonates in osteoporosis. Br J Clin Practice 48:323-326.
13. Rosenthal AK, Cheung HS, Ryan LM 1991 Transforming growth factor betal stimulates inorganic pyrophosphage elaboration by porcine cartilage. Arthritis Rheum 34:904-911.
14. Howell D, Martel-Pelletier J, Pelletier J-P, Morales S, Muniz O 1984 NTP Pyrophosphohydrolase in human chondrocalcinotic and osteoarthritic cartilage. II. Further studies on histologic and subcellular distribution. Arthritis Rheum 27:193-199.
15. Rachow J, Ryan L 1988 Inorganic pyrophosphate metabolism in arthritis. Rheum Dis Clin N Am 14:289-302.
16. Terkeltaub R, Rosenbach M, Fong F, Goding J 1994 A causal link between nucleotide pyrophosphohydrolase overactivity and increased intracellular PPi generation is demonstrated by transfection of cultured fibroblasts and osteoblasts with PC-1 (Plasma Cell Membrane Glycoprotein-1): Relevance to CPPD Deposition Disease. Arthritis Rheum 37:934-941.
17. Huang R, Rosenbach M, Vaughn R, Provvedini D, Rebbe N, Hickman S, Goding J, Terkeltaub R 1994 Expression of the murine plasma cell nucleotide pyrophosphohydrolase PC-1 is shared by human liver, bone and cartilage cells: Regulation of PC-1 expression in osteosarcoma cells by transforming growth factor-beta. J Clin Invest 94:560-567.
18. Jones A, Chuck A, Arie E, Green D, Doherty M 1992 Diseases associated with calcium pyrophosphate deposition disease. Sem Arthritis Rheum 22:188-202.
19. Murray E, Provvedini D, Curran D, Catherwood B, Sussman H, Manolagas S 1987 Characterization of a human osteoblastic cell line (SaOS-2) with high alkaline phosphatase activity J Bone Miner Res 2:231-238.
20. Rodan SB, Wesolowski G, Yoon K, Rodan GA 1989 Opposing effects of fibroblast growth factor and pertussis toxin on alkaline phosphatase, osteopontin, osteocalcin, and Type 1 collagen mRNA levels in ROS 17/2.8 cells. J Biol Chem 264:19934-19941.
21. Shen V, Kohler G, Huang J, Huang SS, Peck WA 1989 An acidic fibroblast growth factor stimulates DNA synthesis, inhibits collagen and alkaline phosphatase synthesis and induces resorption in bone. Bone Miner 7:205-219.
22. Fukayama S, Kearns AK, Skurat RM, Tashjian AH, Bringhurst FR 1991 Protein kinase A-dependent inhibition of alkaline phosphatase release by SaOS-2 human osteoblastic cells: studies in new mutant cell lines that express a cyclic AMP-resistant phenotype. Cell Regulation 2:889-896.
23. Uhler MD, Abou-Chebl A 1992 Cellular concentrations of protein kinase A modulate Prostaglandin and cAMP induction of alkaline phosphatase. J Biol Chem 267:8658-8665.
24. Rao LG, Wylie JN, Sutherland MSK, Murray TM 1994 17β-estradiol and parathyroid hormone potentiate each other's stimulatory effects on alkaline phosphatase activity in SaOS-2 cells in differentiation-dependent manner. Endocrinology 134: 614-619.
25. Oyajobi, BO, Caswell AS, Russell RG 1994. Transforming growth factor β increases ecto-nucleoside triphosphate pyrophosphatase activity of human bone-derived cells. J Bone Miner Res 9:99-109.
26. Narita M, Goji J, Nakamura H, Sano K 1994 Molecular cloning, expression, and localization of a brain-specific phosphodiesterase I/Nucleotide Pyrophosphatase (PD-1a) from rat brain. J Biol Chem 169:28235-28242.
27. Lotz M, Rosen F, McCabe G, Quach J, Blanco F, Dudler J, Solan J, Goding J, Seegmiller JE, Terkeltaub R 1995 IL-1β suppresses TGFβ-induced inorganic pyrophosphatase production and expression of the PPi-generating enzyme PC-1 in human chondrocytes. Proc Natl Acad Sci 92:10364-10368.
28. Manolagas SC, Jilka RL 1995 Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathogenesis of osteoporosis. New Engl J Med 332:305-311.
29. Globus RK, Patterson-Buckendahl P, Gospodarowicz D 1988 Regulation of bovine bone cell proliferation by fibroblast growth factor and transforming growth factor beta. Endocrinology 123:98-105.
30. Globus RK, Plouet J, Gospodarowicz D 1989 Cultured bovine bone cells synthesize basic fibroblast growth factor and store it in their extracellular matrix. Endocrinology 124:1539-1547.
31. 3. J Biol Chem 269:28374-23881.
32. Hurley MM, Abreu C, Harrison JR, Lichtler AC, Raisz LG, Kream BE 1993 Basic fibroblast growth factor inhibits Type 1 collagen gene expression in osteoblastic MC3T3-E1 cells. J Biol Chem 286:5588-5593.
33. Pitaru S, Kotev-Emeth S, Noff ED, Kaffuler S, Savion N 1993 Effects of basic fibroblast growth factor on the growth and differentiation of adult stromal bone marrow cells: enhanced development of mineralized bone-like tissue in culture. J Bone Miner Res 8:919-929.
34. Belli SI, Goding JW 1994 Biochemical characterization of human PC-1, an enzyme possessing alkaline phosphodiesterase I and nucleotide pyrophosphatase activities. Eur J Biochem 226:433-443.
35. Belli SI, Sali A, Goding JW 1994 Divalent cations stabilize the conformation of plasma cell membrane glycoprotein PC-1 (alkaline phosphodiesterase I). Biochem J 304:75-80.
36. Belli SI, van Driel IR, Goding JW 1993 Identification and characterization of a soluble form of the plasma cell membrane glycoprotein PC-1 (5′-nucleotide phosphodiesterase). Eur J Biochem 217:421-428.
37. Hurley MM, Abrew C, Hakeda Y 1995 Basic fibroblast growth factor regulates IGF-1 binding proteins in the clonal osteoblastic cell line MC3T3-E1. J Bone Miner Res 10:222-230.
38. Olmez U, Ryan L, Kurup I, Rosenthal A 1994 Insulin-like growth factor-1 suppresses pyrophosphate elaboration by transforming growth factor b1-stimulated chondrocytes and cartilage. Osteoarthritis Cartilage 2:149-154.
39. Hsu HY, Nicholson AC, Hajjar DP 1994 Basic fibroblast growth factor-induced low density lipoprotein receptor transcription and surface expression. Signal transduction pathways mediated by the bFGF receptor tyrosine kinase. J Biol Chem 269:9213-9320.
40. Savitha G, Salimath BP 1993 Cross-talk between protein kinase C and protein kinase A down-regulates the respiratory burst in polymorphonuclear leukocytes. Cell Sig 5:107-117.
41. Barnes SJ; Conn PM 1993 Cholera toxin and dibutyryl cyclic adenosine 3′,5′-monophosphate sensitize gonadotropin-releasing hormone-stimulated inositol phosphate production to inhibition in protein kinase-C (PKC)-depleted cells: evidence for cross-talk between a cholera toxin-sensitive G-protein and PKC. Endocrinology 133:2756-2760.
42. Balboa MA, Firestein BL, Godson C, Bell KS, Insel PA 1994 Protein kinase C alpha mediates phospholipase D activation by nucleotides and phorbol ester in Madin-Darby canine kidney cells. Stimulation of phospholipase D is independent of activation of polyphosphoinositide-specific phospholipase C and phospholipase A2. J Biol Chem 269:10511-10516.
43. Budworth J; Gescher A 1995 Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors. FEBS Lett 362:139-142.
44. Ringbom-Anderson T, Akerman KE 1992 A phorbol ester induces secretion of alkaline phosphatase activity in human osteosarcoma cells. Calcif Tissue Int 50:533-540.
45. Rebbe N, Tong B. Finley EM, Hickman S 1991 Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1. Proc Natl Acad Sci 88:5192-5196.
46. Bissonnette M, Wali RK, Hartmann SC, Niedziela SM, Roy HK, Tien XY, Sitrin MD, Brasitus TA 1995 1.25-Dihydroxyvitamin D3 and 12-O-tetradecanoyl phorbol 13-acetate cause differential activation of Ca(2+)-dependent and Ca(2+)-independent isoforms of protein kinase C in rat colonocytes. J Clin Invest 95:2215-2221.
47. Taylor CW, Blakeley DM, Corps AN, Berridge MJ, Brown KD 1988 Effects of pertussis toxin on growth factor-stimulated inositol phosphate formation and DNA synthesis in Swiss 3T3 cells. Biochem J 249:917-920.
48. Taussig R, Tang W-J, Hepler JR, Gilman AG 1994 Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases. J Biol Chem 269:6093-6100.
49. Jingushi S, Heydesmann A, Kana SK, Macey LR, Bolander ME 1990 Acidic fibroblast growth factor (a FGF) injection stimulates cartilage enlargement and inhibits cartilage gene expression in rat fracture healing. J Orthoped Res 8:364-371.
50. Aspenberg P, Lohmander LS 1989 Fibroblast growth factor stimulates bone formation. Acta Orthoped Scand 60:473-476.
51. Simmons HA, Raisz LG 1991 Effects of acid and basic fibroblast growth factor and heparin on resoprtion of cultured fetal rat long bones. J Bone Miner Res 6:1301-1305.
52. Derfus BA, Rachow JW, Mandel NS, Boskey AL, Buday M, Kushnaryov VM, Ryan LM 1992 Articular cartilage vesicles generate calcium pyrophosphate dihydrate-like crystals in vitro. Arthritis Rheum 35:231-240.
53. Hickman S, Wong-Yip YP, Rebbe N, Greco JM 1985 Formation of lipid-linked oligosaccharides by MOPC 315 plasmacytoma cells. Decreased synthesis by a nonsecretory variant. J Biol Chem 260:6096-6106.
54. Fukui S, Yoshida H, Yamashina I 1981 Sulfohydrolytic Degradation of 3′-phosphoadenosine 5′-phosphosulfate (PAPS) and adenosine 5′-phosphosulfate (APS) by enzymes of a nucleotide pyrophosphatase nature. J Biochem 90:1537-1540.
55. Maddux B, Sbraccia P, Kumakura S, Sasson S, Youngren J, Fisher A, Spencer S, Grupe A, Henzel W, Stewart T, Reaven G, Goldfine I 1995 Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus. Nature 373:448-451.
56. Kuo M-D, Huang SS, Huang JS 1990 Acidic fibroblast growth factor receptor purified from bovine liver is a novel protein tyrosine kinase. J Biol Chem 265:16455-16463.
57. Oda Y, Kuo M-D, Huang SS, Huang JS 1991 The plasma cell membrane glycoprotein kinase stimulated by acidic fibrobiast growth factor. J Biol Chem 266:16791-16795.