The pathogenesis of gonococcal urethritis in men: Confocal and immunoelectron microscopic analysis of urethral exudates from men infected with Neisseria gonorrhoeae

Journal of Infectious Diseases

Volumn 173, Issue 3, 1996, Pages 636-646

  Apicella, Michael A ^a   Ketterer, Margaret ^b   Lee, Frank K N ^b   Zhou, Daoguo ^b   Rice, Peter A ^b   Blake, Milan S ^b  

^a UNIVERSITY OF IOWA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; EXUDATE; GONOCOCCAL URETHRITIS; HUMAN; IMMUNOELECTRON MICROSCOPY; IMMUNOFLUORESCENCE TEST; MALE; NEISSERIA GONORRHOEAE; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0030019778     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/173.3.636     Document Type: Article

References (28)

1. Stone JL, Vernon SK, Warren GH. Cultivation and survival studies of Neisseria gonorrhoeae in a human diploid cell strain. Yale J Biol Med 1974; 47:291-6.
2. Waitkins SA, Flynn J. Intracellular growth and type variations of Neisseria gonorrhoeae in tissue cell-culture. J Med Microbiol 1973;6:399-403.
3. McGee ZA, Johnson AP, Taylor-Robinson D. Pathogenic mechanisms of Neisseria gonorrhoeae: observations on damage to human fallopian tube culture by gonococci colony type 1 or type 4. J Infect Dis 1981;143:413-22.
4. Ward ME, Watt PJ, Robertson JN. The human fallopian tube: a laboratory model for gonococcal infection. J Infect Dis 1974; 129:650-9.
5. Ward ME, Watt PJ. Adherence of Neisseria gonorrhoeae to urethral mucosal cells: an electron microscopic study of human gonorrhea. J Infect Dis 1972; 126:601-5.
6. Ovcinnikov NM, Delektorskij VV, Dmitrev GA. Ultrastructure of gonococci in acute, chronic and asymptomatic gonorrhoeae. Br J Vener Dis 1976;52:230-45.
7. Novotny P, Short JA, Walker PD. An electron microscopic study of naturally occurring and cultured cells of Neisseria gonorrhoeae. J Med Microbiol 1975;8:413-27.
8. Farzadegan H, Roth IL. Scanning electron microscopy and freeze-etching of gonorrhoeal urethral exudates. Br J Vener Dis 1975;51:83-91.
9. Apicella MA, Shero M, Breen, et al. Modification by sialic acid of Neisseria gonorrhoeae lipooligosaccharide epitope expression in human ure-thral exudates: an immunoelectron microscopic analysis. J Infect Dis 1990; 162:506-12.
10. Shaw JH, Falkow S. Model for invasion of human tissue culture cells by Neisseria gonorrhoeae. Infect Immun 1988;56:1625-32.
11. van Putten JPM, Paul SM, Robertson BD, Schwann ET. Dynamics of the interaction between gonococci and epithelial cells. In: Proceedings of the IX International Pathogenic Neisseria Conference (Winchester, UK). Shoreham by the Sea, UK: SCC Publishers, 1994:230.
12. Weel JFL, van Putten JPM. Fate of the major outer membrane protein P.IA in early and late events of gonococcal infection of epithelial cells. Res Microbiol 1991; 142:985-93.
13. Chen JC, Bavoil P, Clark VL. Enhancement of the invasive ability of Neisseria gonorrhoeae by contact with HeclB, an adenocarcinoma endometrial cell line. Mol Microbiol 1991; 5:1531-8.
14. van Putten JP. Phase variation of lipopolysaccharide directs interconversion of invasive and immuno-resistant phenotypes of Neisseria gonorrhoeae. EMBO J 1993; 12:4043-51.
15. 2 chemotype LPS and do not enter epithelial host cells. Mol Microbiol 1995; 15:267-75.
16. Griffiss JM, Lammel CJ, Zhao S, Wang J, Dekker NP, Brooks GF. Pili and opa are required for HEC-l-b cell microvillus elongation and engulfment of Neisseria gonorrhoeae. In: Proceedings of the IX International Pathogenic Neisseria Conference (Winchester, UK). Shoreham by the Sea, UK: SCC Publishers, 1994:76-9.
17. Porat N, Apicella MA, Blake MS. Neisseria gonorrhoeae utilizes and enhances the biosynthesis of the asialoglycoprotein receptor expressed on the surface of the hepatic HepG2 cell line. Infect Immun 1995;63:1498-1506.
18. Porat N, Apicella MA, Blake MS. A lipoligosaccharide-binding site on HepG2 cells similar to the gonococcal opacity associated protein Opa. Infect Immun 1995;63:2164-72.
19. Matsumoto B. Cell applications of confocal microscopy. Methods Cell Biol 1993;38:379.
20. Horn W, Hansmann C, Federlin K. An improved fluorochrome microassay for the detection of living and non-living intracellular bacteria in human neutrophils. J Immunol Meth 1985;83:233-40.
21. Hoagland RP. Molecular probes. In: Handbook of fluorescent probes and research chemicals. Eugene, OR: Molecular Probes, 1992-1994:421.
22. Gardner V, Folberg R, Beck S, Knosp B, Moninger T, Moore K. Three-dimensional relationships between tumor cells and microcirculation with double cyanine immunolabeling, laser scanning confocal microscopy, and computer assisted reproduction: an alternative to cast corrosion preparations. J Histochem Cytochem 1994;42:681-6.
23. Damasio H, Frank R. Three dimensional in vivo mapping of brain lesions in humans. Arch Neurol 1992;49:137-43.
24. Westover L. Footprint evaluation for volume rendering. Comput Graph 1990;24:367-76.
25. Goldberg MB, Sansonetti PJ. Shigella subdivision of the cellular cytoskeleton: a strategy for epithelial colonization. Infect Immun 1993;61:4941-6.
26. Portnoy DA, Jones S. The cell biology of Listeria monocytogenes infection (escape from a vacuole). Ann NY Acad Sci 1994; 730:15-25.
27. Cohen MS, Isbey S, Chamiga L, et al. In vivo experiments with Neisseria gonorrhoeae. In: Proceedings of the IX International Pathogenic Neisseria Conference (Winchester, UK), Shoreham by the Sea, UK: SCC Publishers, 1994:223-4.
28. Schneider H, Cross AS, Kuschner RA, et al. Experimental human gonococcal urethritis: 250 Neisseria gonorrhoeae MS11mkC are infective. J Infect Dis 1995; 172:180-5.