Familial psychiatric presentation of Huntington's disease

Journal of Medical Genetics

Volumn 33, Issue 2, 1996, Pages 128-131

  Lovestone, S ^a   Hodgson, S ^b   Sham, P ^a   Differ, A M ^b   Levy, R ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

Author keywords

Huntington's disease; Psychosis; Schizophrenia

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; HUNTINGTON CHOREA; MALE; ONSET AGE; PRIORITY JOURNAL; PSYCHIATRIC TREATMENT; PSYCHOSIS; SCHIZOPHRENIA;

EID: 0030019674     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.33.2.128     Document Type: Article

References (15)

1. Huntington's Disease Collaborative Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993; 72:971-83.
2. Watt DC, Seller A. A clinico-genetic study of psychiatric disorder in Huntington's chorea. Psychol Med 1993;suppl 23:1-46.
3. Dewhurst K, Oliver J, Trick K, McKnight A. Neuropsychiatric aspects of Huntington's disease. Confin Neurol 1969;31:255-8.
4. Bolt JMW. Huntington's chorea in the west of Scotland. Br J Psychiatry 1970;116:259-70.
5. Holstein S, Franz M, Jansen B, Chase G, Holstein M. Conduct disorder and affective disorder among offspring of patients with Huntington's disease. Psychol Med 1983; 13:45-52.
6. Folstein S, Abbott M, Chase G, Jansen B, Holstein M. The association of affective disorder with Huntington's disease: in a case series and in families. Psychol Med 1983;13: 537-42.
7. Holstein S, Folstein M. Psychiatric features of Huntington's disease: recent approaches and findings. Psychiatr Dev 1983;2:193-206.
8. Dewhurst K, Oliver JE, McKnight AL. Socio-psychiatric consequences of Huntington's disease. Br J Psychiatry 1970;116:255-8.
9. Besson PS, Ebmeier KP, Simpson S. The clinical manifestation of mental disorder in Huntington's disease: a retrospective case record study of disease progression. Acta Psychiatr Scand 1991;83:53-60.
10. Jensen P, Sorensen SA, Fenger K, Bolwig TG. A study of psychiatric morbidity in patients with Huntington's disease, their relatives and controls. Admissions to psychiatric hospitals in Denmark from 1969 to 1991. Br J Psychiatry 1993;163:790-7.
11. Baxter LR, Mazziotta JC, Pahl JJ, et al. Psychiatric, genetic and positron emission tomographic evaluations of persons at risk for Huntington's disease. Arch Gen Psychiatry 1992; 49:148-54.
12. Koide R, Ikeuchi T, Onodera O, et al. Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA). Nature Genet 1994;6:9-13.
13. Nagafuchi S, Yanagisawa H, Sato K. Dentatorubral and pallidoluysian atrophy; expansion of an unstable CAG trinucleotide on chromosome 12p. Nature Genet 1994;6: 14-18.
14. Jones CT, Morris S, Yates CM, et al. Mutation in codon 713 of the β amyloid precursor protein gene presenting with schizophrenia. Nature Genet 1992;1:306-9.
15. St Clair D. Expanded CAG trinucleotide repeat of Huntington's disease gene in a patient with schizophrenia and normal striatal histology. J Med Genet 1994;31:658-9.