No-Carrier-Added (4-Fluoro-3-[131I]iodobenzyl)guanidine and (3-[211At]Astato-4-fluorobenzyl)guanidine

Bioconjugate Chemistry

Volumn 7, Issue 1, 1996, Pages 102-107

  Vaidyanathan, Ganesan ^a   Affleck, Donna J ^a   Zalutsky, Michael R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HALOGENATION; OXIDATION;

4-FLUOROTOLUENE; AQUEOUS MEDIA; BY-PRODUCT FORMATION; CONDITION; N-CHLOROSUCCINIMIDE; RADIOCHEMICAL YIELD; RADIOIODINATION; RETENTION TIME; SILICON PRECURSORS; TRIMETHYLSILYL;

HYDROGEN PEROXIDE;

EID: 0030019363     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc950078i     Document Type: Article

References (24)

1. 125I]iodobenzylguanidine in the human neuroblastoma cell line SK-N-SH. Cancer Res. 45, 6366-6370.
2. 18F)fluorobenzylguanidine. Nucl. Med. Biol. 21, 97-103.
3. Glowniak, J. V., Turner, F. E., Grav, L. L. Palac, R. T., LagunasSolar, M. C ., and Woodward, W. R. (1969) Iodine-123 metaiodobenzylguanidine imaging of the heart in idiopathic comgestive cardiomyopathy and cardiac transplants. J. Nucl. Med. 30, 1182-1191.
4. Hoffmann, R. W. (1967) Dehydrobenzenes and Cycloalkynes, Organic Chemistry, VoL 11, p 182, Academic Press, New York.
5. Hudrlik, P. F ., and Agwaramgbo, E. L. O. (1988) Elimination reactions of β-funaional organosilicon compounds. In Silicon Chemistry (J. Y. Corey, E. R. Corey. and P. P. Gaspar, Eds.) pp 95-104. Ellis Horwood Limited, Chichester, England.
6. Kemshead, J. T., Pizer, P. L ., and Patel, K. (1990) Neuroblastoma: Perspectives for future research. In Neuroblastoma: Tumor Biology and Therapy (C. Pochedly, Ed.) pp 381 -395, CRC Press, Boca Raton, FL.
7. 76]MBBG). Nucl. Med. Biol. 21, 49-55.
8. Mairn, R., Angerson, W. J., Babich, J. W ., and Murray, T. (1991) Differential penetration of targetting agents into multicellular spheroids derived from human neuroblastoma. In Advances in Neuroblastoma Research 3 (Progress in Clinical and Biological Research, Vol. 366) (A. E. Evans, G. J. D'Angio, A. G. Knudson, Jr ., and R. C. Seeger, Eds.) pp 495-501, WileyLiss, Inc., New York.
9. McEwan, A. J., Wyeth, P ., and Ackery, D. (1986) Radioiodinated iodobenzylguanidines for diagnosis and therapy. Appl. Radiat. Isot. 37, 765-775.
10. 131l-radiolabelled meta-iodobenzylguanidine (MIBG) for the targeted radiotherapy of neuroblastoma. Br. J. Radiol. 64, 428-434.
11. 134I-mIBG positron emission. Br. J. Radiol. 65, 787-791.
12. 123I-MIBG. Med, Pediatr. Oncol. 15, 170-177.
13. Shulkin, B. L., Shapiro, B., Francis, I., Door, R., Shew, S.-W ., and Sisson, J. C. (1986) Primary extra-adrenal pheochromocytoma positive 1-123 MIBG imaging with negative 1-131 MIBG imaging. Clin. Nucl. Med. 11, 851-854.
14. Sisson, J. C., Hutchinson, R. J., Shapiro, B., Zasadny, K. R., Normolle, D., Wieland, D. M., Wahl, R. L., Singer, D. A., Mallete, S. A ., and Mudgett, E. E. (1990) Iodine- 125-MIBG to treat neuroblastoma: Preliminary report. J. Nucl. Med. 31, 1479-1485.
15. Smets, L. A., Loesberg, C., Janssen, M., Metwally, E. A ., and Huiskamp, R. (1989) Active uptake and extravesicular storage of m-iodobenzylguanidine in human neuroblastoma SK-N-SH cells. Cancer Res. 49, 2941-2944.
16. 211At]astatobenzylguanidine on neuroblastoma cell. Cancer Res. 54, 5414-5419.
17. 211At]Astatobenzyl) guanidine: Synthesis via Astato Demetalation and Preliminary in Vitro and in Vivo Evaluation. Bioconjugate Chem. 3, 499-503.
18. 131I]iodobenzylguanidine. Appl. Radiat. Isot. 44, 621-628.
19. 18]F]Fluoro-3-iodobenzl)guanidine, a Potential MIBG Analogue for Positron Emission Tomography. J. Med. Chem. 37, 3655-3662.
20. 18F]FIBG): Potential MIBG analogs for PET imaging and therapy of neuroendocrine tumors. XV1th International Cancer Congress, October 30-November 5, New Delhi, India.
21. 18]fluoro-3-iodobenzylguanidine as a positronemitting analog of MIBG. J. Nucl. Med. 36, 644-650.
22. Valette, H., Loc'h, C., Mardon, K., Bendriem, B., Merlet, P., Fuseau, C., Sabry, S., Raffel, D., Maziére, B ., and Syrola, A. (1993) Bromine-76-metabromobenzylguanidine: A PET radiotracer for mapping mapping sympathetic nenes of the heart. J. Nucl. Med. 34, 1739-1744.
23. Wieland, D. M. (1986) Radiopharmaceutical Design: The Adrenal Medulla and Its Diseases. In Radiopharmaceutical: Progress and Clinical Perspectives (A. R. Fritzberg, Ed.) Vol. 1, pp 117-153, CRC Press, Inc., Boca Raton, FL.
24. 2 fragments with the alpha particle emitting nuclide astatine-211: preservation of immunoreactivity and in vivo localizing capacity. Proc. Natl. Acad. Sci. U.S.A. 86, 7149-7153.