Localization of merosin in the normal human brain: Implications for congenital muscular dystrophy with merosin deficiency

Journal of Submicroscopic Cytology and Pathology

Volumn 28, Issue 1, 1996, Pages 1-4

  Villanova, M ^a,d   Malandrini, A ^a   Toti, P ^a   Salvestroni, R ^a   Six, J ^b   Martin, J J ^c   Guazzi, G G ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d Laboratorio di Neuropatogia   (Italy)

Author keywords

Blood brain barrier (BBB); Congenital muscular dystrophy; Merosin; Muscle biopsy

Indexed keywords

LAMININ;

ADULT; ANTIBODY SPECIFICITY; ARTERIOLE; ARTICLE; BASEMENT MEMBRANE; BRAIN; BRAIN ARTERY; BRAIN LEVEL; CAPILLARY; CHEMISTRY; COMPARATIVE STUDY; HUMAN; METABOLISM; MIDDLE AGED; MUSCULAR DYSTROPHY; NEWBORN; ULTRASTRUCTURE; VASCULARIZATION;

ADULT; ARTERIOLES; BASEMENT MEMBRANE; BRAIN; BRAIN CHEMISTRY; CAPILLARIES; CEREBRAL ARTERIES; HUMANS; INFANT, NEWBORN; LAMININ; MIDDLE AGED; MUSCULAR DYSTROPHIES; ORGAN SPECIFICITY;

EID: 0030019062     PISSN: 11229497     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. DUBOWITZ V., MERCURI E., MUNTONI F., PHILIPOT J., SEWRY C.A. and SHORER Z., 1995. Peripheral and central nervous system involvement in merosin-deficient congenital muscular dystrophy. Neurology, 45 (suppl. 4), A407.
2. ECHENNE B., PAGES M. and MARTY-DOUBLE C., 1984. Congenital muscular dystrophy with cerebral white matter spongiosis. Brain Dev., 6, 491-495.
3. EHRIG K., LEIVO I., ARGRAVES K.S., RUOSLAHTI E. and ENGVALL E., 1990. Merosin, a tissue-specific basement membrane protein, is a laminin-like protein. Proc. Natl. Acad. Sci., 87, 3264-3268.
4. ENGVALL E., 1993. Laminin variants: why, where and when? Kidney Int., 43, 2-6.
5. HILLAIRE D., LECLERC A., FAURE S., TOPALOGLU H., CHIANNILKULCHAÏ N., GUICHENEY P., GRINAS L., LEGOS P., PHILIPOT J., EVANGELISTA T., ROUTON M.C., MAYER M., PELLISSIER J.E, ESTOURNET B., BAROIS A., HENTATI F., FEINGOLD N., BECKMANN J.S., DUBOVITZ V., TOME F.M.S. and FARDEAU M., 1994. Localization of merosin-negative congenital muscular dystrophy to chromosome 6q by homozygosity mapping. Hum. Mol. Genet., 3, 1657-1661.
6. JONES W.M. and COWAN E.G., 1977. Brain Tissue. In: 'Histology'. Weiss L. and Creep R. eds., Mc Graw Hill.
7. LEIVO I. and ENGVALL E., 1988. Merosin, a protein specific for basement membrane of Schwann cells, striated muscle, and trophoblast, is expressed late in nerve and muscle development. Proc. Natl. Acad. Sci., 85, 1544-1548.
8. NOAKES P.G., MINER J.H., GAUTAM M., CUNNINGHAM J.M., SANES J.R. and MERLIE J.P., 1995. The renal glomerulus of mice lacking s-lamimn/laminin B2: nephrosis despite molecular compensation by laminin B1. Nature Genet., 10, 400-405.
9. SASAKI M., KLEINMAN H.K., HUBER H., DEUTZMANN R. and YAMADA Y., 1988. Laminin, a multidomain protein. J. Biol. Chem., 263, 16536-16544.
10. TOME F.M.S., EVANGELISTA T., LECLERC A., SUNADA Y., MANOLE E., ESTOURNET B., BAROIS A., CAMPBELL K.P. and FARDEAU M., 1994. Congenital muscular dystrophy with merosin deficiency. C.R. Acad. Sci. Paris, 317, 351-357.
11. TREVISAN C.P., MARTINELLO F., FERRUZZA E. and ANGELINI C., 1995. Divergence of central nervous system involvement in 2 Italian sisters with congenital muscular dystrophy, a clinical and neuroradiological follow-up. Eur. Neurol., 35, 230-235.
12. VIRTANEN I., LAITINEN L. and KORHONEN M., 1995. Differential expression of laminin polypeptides in developing and adult human kidney. J. Histochem. Cytochem., 43, 621-628.