No significant changes in the expression of the fas, fasl, bcl-2 and bax genes in apoptosis of an erythroleukemic cell line by p53

International Journal of Oncology

Volumn 9, Issue 2, 1996, Pages 269-277

  Kato, Mitsuo V ^a   Sato, Hiromi ^a   Ishizaki, Kanji ^b   Anzai, Hiroko ^a   Nagayoshi, Mariko ^a   Ikawa, Yoji ^a,c  

^a RIKEN TSUKUBA INSTITUTE   (Japan)

^b AICHI CANCER CENTER HOSPITAL   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Erythroleukemia; p53

Indexed keywords

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ERYTHROLEUKEMIA CELL; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSACTIVATION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

EID: 0030018618     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.9.2.269     Document Type: Article

References (58)

1. Greenblatt MS, Bennett WP, Hollstein M and Harris CC: Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res 54: 4855-4878, 1994.
2. Malkin D, Li FP, Strong LC, Fraumeni JJ, Nelson CE, Kim DH, Kassel J, Gryka MA, Bischoff FZ, Tainsky MA and Friend SH: Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250: 1233-1238, 1990.
3. Srivastava S, Zou ZQ, Pirollo K, Blattner W and Chang EH: Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 348: 747-749, 1990.
4. Eliyahu D, Goldfinger N, Panhasi-Kimhi O, Shaulshy G, Skurnik Y, Arai N, Rotter V and Oren M: Meth A fibrosarcoma cells express two transforming mutant p53 species. Oncogene 3: 313-321, 1988.
5. Finlay CA, Hinds PW, Tan T-H, Eliyahu D, Oren M and Levine AJ: Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol 8: 531-539, 1988.
6. Chen PL, Chen YM, Bookstein R and Lee WH: Genetic mechanisms of tumor suppression by the human p53 gene. Science 250: 1576-1580, 1990.
7. Eliyahu D, Michalovitz D, Eliyahu S, Panhasi-Kimhi O and Oren M: Wild-type p53 can inhibit oncogene-mediated focus formation. Proc Natl Acad Sci USA 86: 8763-8767, 1989.
8. Finlay CA, Hinds PW and Levine AJ: The p53 proto-oncogene can act as a suppressor of transformation. Cell 57: 1083-1093, 1989.
9. Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montogomery CA Jr, Butel JS and Bradley A: Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356: 215-221, 1992.
10. Livingstone LR, While A, Sprouse J, Livanos E, Jacks T and Tlsty TD: Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70: 923-935, 1992.
11. Harvey M, Sands AT, Weiss RS, Hegi ME, Wisemann RW, Pantazis P, Giovanella BC, Tainsky MA, Bradley A and Donehower LA: In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice. Oncogene 8: 2457-2467, 1993.
12. Tsukada T, Tomooka Y, Takai S, Ueda Y, Nishikawa S-i, Yagi T, Tokunaga T, Takeda N, Suda Y, Abe S, Matsuo I, Ikawa Y and Aizawa S: Enhanced proliferative potential in culture of cells from p53-deficient mice. Oncogene 8: 3313-3322, 1993.
13. Yin Y, Tainsky MA, Bischoff FZ, Strong LC and Wahl GM: Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70: 937-948, 1992.
14. Kern SE, Kinzler KW, Bruskin A, Jarosz D, Friedman P, Prives C and Vogelstein B: Identification of p53 as a sequence-specific DNA-binding protein. Science 252: 1708-1711, 1991.
15. Kern SE, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW and Vogelstein B: Oncogenic forms of p53 inhibit p53-regulated gene expression. Science 256: 827-830, 1992.
16. El-Dairy WS, Tokino T, Veculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW and Vogelstein B: WAF1, a potential mediator of p53 tumor suppression. Cell 75: 817-825, 1993.
17. Wu X, Bayle JH, Olson D and Levine AJ: The p53-mdm-2 autoregulatory feedback loop. Gene Develop 7: 1126-1132, 1993.
18. Weintraub H, Haushka S and Tapscott S: The MCK enhancer contains a p53 responsive element. Proc Natl Acad Sci USA 88: 4570-4571, 1991.
19. Zambetti GP, Bargonetti J, Walker K, Prives C and Levine AJ: Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element. Gene Develop 6: 1143-1152, 1992.
20. Kastan MB, Zhan Q, El-Dairy ES, Carrier F, Jacks T, Walsh WV, Plunkett BS, Vogelstein B and Fornace AJ Jr: A mammalian cell cycle checkpoint pathway utilizing p53 and gadd45 is defective in ataxia-telangiectasia. Cell 71: 587-597, 1992.
21. Okamoto K and Beach D: Cyclin G is a transcriptional target of the p53 tumor suppressor protein. EMBO J 13: 4816-4822, 1994.
22. Miyashita T and Reed JC: Tumor suppressor p53 is a direct transcriptional activator of the human box gene. Cell 80: 293-299, 1995.
23. 1 cyclin-dependent kinases. Cell 75: 805-816, 1993.
24. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R and Beach D: p21 is a universal inhibitor of cyclin kinases. Nature 366: 701-704, 1993.
25. Gu Y, Turck CW and Morgan DO: Inhibition of CDK2 activity in vivo by an associated 20 K regulatory subunit. Nature 366: 707-710, 1993.
26. Waga S, Hannon GJ, Beach D and Stillman B: The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369: 574-578, 1994.
27. Noda A, Ning Y, Venable SF, Pereira-Smith OM and Smith JR: Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 211: 90-98, 1994.
28. Oltvai ZN, Milliman CL and Korsmeiyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619, 1993.
29. Miyashita T, Krajewski S, Krajewska M, Wang HG, Lin HK, Liebermann DA, Hoffman B and Reed JC: Tumor suppressor p53 is a regulator of bcl-2 and box gene expression in vitro and in vivo. Onogene 9: 1799-1805, 1994.
30. Owen-Schaub LB, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, Deisseroth AB, Zhang WW, Kruzel E and Radinsky R: Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 15: 3032-3040, 1995.
31. Lane DP: p53, guardian of the genome. Nature 358: 15-16, 1992.
32. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B and Craig RW: Participation of p53 protein in the cellular response to DNA damage. Cancer Res 51: 6304-6311, 1991.
33. Kuerbitz SJ, Plunkett BS, Walsh WV and Kastan MB: Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci USA 89: 7491-7495, 1992.
34. Savitsky K, Bar-Shira A, Gilad S, Rotman G, Ziv Y, Vanagaite L, Tagle DA, Smith S, Uziel T, Sfez S, Ashkenazi M, Pecker I, Frydman M, Hamik R, Patanjali SR, Simmons A, Clines GA, Sartiel A, Gatti RA, Chessa L, Sanal O, Lavin MF, Jaspers NGJ, Malcolm A, Taylor R, Arlett CF, Miki T, Weissman SM, Lovett M, Collins FS and Shiloh Y: A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268: 1749-1753, 1995.
35. Smith ML, Chen IT, Zhan Q, Bae I, Chen CY, Gilmer TM, Kastan MB, O'Connor PM and Fornace AJ Jr: Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Science 266: 1376-1380, 1994.
36. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A and Oren M: Nature 352: 345-347, 1991.
37. Lowe SW, Schmitt EM, Smith SW, Osborne BA and Jacks T: p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849, 1993.
38. Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML and Wyllie AH: Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362: 849-852, 1993.
39. Pan H and Griep AE: Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Gene Develop 8: 1285-1299, 1994.
40. Morgenbesser SD, Williams BO, Jacks T and DePinho RA: p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371: 72-74, 1994.
41. Howes KA, Ransom N, Papermaster DS, Lasudry JGH, Albert DM and Windle JJ: Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Gene Develop 8: 1300-1310, 1994.
42. Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S and Dyke TV: p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 78: 703-711, 1994.
43. White E: p53, guardian of Rb. Nature 371: 21-22, 1994.
44. Michalovitz D, Halevy O and Oren M: Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 62: 671-680, 1990.
45. Martinez J, Georgoff I, Martinez J and Levine AJ: Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Gene Develop 5: 151-159, 1991.
46. Gannon JV and Lane DP: Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport. Nature 349: 802-806, 1991.
47. Amanuma H, Katori A, Obata M, Sagata N and Ikawa Y: Complete nucleotide sequence of the gene for the specific glycoprotein (gp55) of Friend spleen focus-forming virus. Proc Natl Acad Sci USA 80: 3913-3917, 1983.
48. Kawa Y, Yoshida M and Yoshikura H: Identification of protein specific to Friend strain of spleen focus-forming virus (SFFV). Proc Jpn Acad B 54: 651-655, 1978.
49. Li J-P, D'Andrea AD, Lodish HF and Baltimore D: Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor. Nature 343: 762-764, 1990.
50. Aizawa S, Suda Y, Furuta Y, Yagi T, Takeda N, Watanabe N, Nagayoshi M and Ikawa Y: Env-derived gp55 gene of Friend spleen focus-forming virus specifically induces neoplastic proliferation of erythroid progenitor cells. EMBO J 9: 2107-2116, 1990.
51. Xu X, Yamamur Y, Tsukada T, Yoshida MA, Senda H, Nagayoshi M, Ikeuchi T and Ikawa Y: A mouse erythro-leukemia cell line possessing friend spleen focus-forming virus gp55 transgene and temperature-sensitive mutant p53 gene. Jpn J Cancer Res 86: 284-291, 1995.
52. Sambrook J, Fritsch EF and Maniatis T: Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989.
53. Chomczynski P and Sacchi N: Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
54. Innis MA, Gelfand GH, Sninsky JJ and White TJ: PCR protocols: a guide to methods and applications. Academic Press Inc, San Diego, CA, 1990.
55. Funk WD, Pak DT, Karas RH, Wright WE and Shay JW: A transcriptionally active DNA-binding site for human p53 protein complexes. Mol Cell Biol 12: 2866-2871, 1992.
56. Johnson P, Chung S and Benchimol S: Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin. Mol Cell Biol 13: 1456-1463, 1993.
57. Camman CE, Gilmer TM, Coutts SB and Kastan MB: Growth factor modulation of p53-mediated growth arrest versus apoptosis. Gene Develop 9: 600-611, 1995.
58. Fornace AJ Jr, Nebert DW, Hollander MC, Luethy JD, Papathanasiou M, Fargnori J and Holbrook NJ: Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents. Mol Cell Biol 9: 4196-4203, 1989.