Forced over-expression of the myeloid zinc finger gene MZF-1 inhibits apoptosis and promotes oncogenesis in interleukin-3-dependent FDCP.1 cells

Leukemia

Volumn 10, Issue 6, 1996, Pages 1049-1050

  Hromas, R ^a   Boswell, S ^a   Shen, R N ^b   Burgess, G ^a   Davidson, A ^a   Cornetta, K ^a   Sutton, J ^a   Robertson, K ^b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Apoptosis; Oncogenesis; Retroviral gene transfer; Transcription factors

Indexed keywords

INTERLEUKIN 3; ZINC FINGER PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW CELL; CARCINOGENESIS; CONTROLLED STUDY; GENETIC TRANSDUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS;

EID: 0030018316     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Hromas R et al. A retinoic acid-responsive zinc finger gene, MZF-1, preferentially expressed in myeloid cells. J Biol Chem 1991; 266: 14183-14187.
2. Bavisotto L et al. Anti-sense oligonucleotides from the stage-specific zinc finger gene MZF-1 inhibit granulopoiesis in vitro. J Exp Med 1991; 174: 1097-1101.
3. Morris J, Hromas R, Rauscher III, F. Characterization of the DNA binding properties of the myeloid zinc finger gene MZF-1: two independent DNA-binding domains recognize two DNA consensus sequences with a common G-rich core. Mol Cell Biol 1994; 14: 1786-1795.
4. Hromas R et al. Aberrant expression of the myeloid zinc finger gene, MZF-1, is oncogenic. Cancer Res 1995; 55: 3610-3614.
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