Clinical implications of nucleic acid amplification methods for the diagnosis of viral infections of the nervous system

Journal of NeuroVirology

Volumn 2, Issue 3, 1996, Pages 175-190

  Weber, Thomas ^a,c   Frye, Stephan ^a,b   Bodemer, Monika ^a   Otto, Markus ^a   Lüke, Wolfgang ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b GERMAN PRIMATE CENTER   (Germany)

^c Marienkrankenhaus Hamburg   (Germany)

Author keywords

Aptamer; Cerebrospinal fluid; Encephalitis; Meningitis; Polymerase chain reaction

Indexed keywords

MUMPS VACCINE; VIRUS DNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; ASEPTIC MENINGITIS; B CELL LYMPHOMA; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID; CYTOMEGALIC INCLUSION BODY DISEASE; CYTOMEGALOVIRUS; DIAGNOSTIC TEST; ENTEROVIRUS INFECTION; EPSTEIN BARR VIRUS; GENE AMPLIFICATION; GUILLAIN BARRE SYNDROME; HERPES SIMPLEX VIRUS; HUMAN; JC VIRUS; MENINGITIS; MENINGOENCEPHALITIS; MYELITIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VARICELLA ZOSTER VIRUS; VIRUS ENCEPHALITIS; VIRUS INFECTION;

CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; DNA VIRUSES; ENTEROVIRUS; HERPES; HERPESVIRIDAE; HUMAN HERPES VIRUS; HUMAN HERPESVIRUS 3; HUMAN HERPESVIRUS 4; HUMAN IMMUNODEFICIENCY VIRUS; JC VIRUS; MUMPS VIRUS; SIMPLEXVIRUS;

EID: 0030018202     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289609146880     Document Type: Article

References (168)

1. Aksamit AJ, Kost S (1994). PCR detection of JC virus in PML and control CSF. In: Neuroscience of HIV Infection; Basic and Clinical Frontiers. Vancouver.
2. Alain S, Mazeron MC, Pepin JM, Morinet F, Raskine L, Sanson-Le-Pors MJ (1993). Rapid detection of cytomegalovirus strains resistant to ganciclovir through mutations within the gene UL97. Mol Cell Probes 7: 487-495.
3. Amlie-Lefond C, Kleinschmidt-DeMasters BK, Mahalingam R, Davis LE, Gilden DH (1995). The vasculopathy of varicella-zoster virus encephalitis. Ann Neurol 37: 784-790.
4. Anderson NE, Powell KF, Croxson MC (1993). A polymerase chain reaction assay of cerebrospinal fluid in patients with suspected herpes simplex encephalitis. J Neurol Neurosurg Psychiatry 56: 520-525.
5. Ando Y, Kimura H, Miwata H, Kudo T, Shibata M, Morishima T (1993). Quantitative analysis of herpes simplex virus DNA in cerebrospinal fluid of children with herpes simplex encephalitis. J Med Virol 41: 170-173.
6. Antinori A, De Luca A, Ammassari A, Cingolani A, Murri R, Colosimo G, et al. (1994). Failure of cytarabine and increased JC virus-DNA burden in the cerebrospinal fluid of patients with AIDS-related progressive multifocal leucoencephalopathy. AIDS 8: 1022-1024.
7. Asano Y, Yoshikawa T, Kajita Y, Ogura R, Suga S, Yazakli T, et al. (1992). Fatal encephalitis/ encephalopathy in primary human herpesvirus-6 infection. Arch Dis Child 67: 1484-1485.
8. Åström K-E, Mancall EL, Richardson EP (1958). Progressive multifocal leuko-encephalopathy. A hitherto unrecognized complication of chronic lymphatic leukaemia and Hodgkin's disease. Brain 81: 93-111.
9. Aurelius E (1993). Herpes simplex encephalitis. Early diagnosis and immune activation in the acute stage and during long-term follow-up. Scand J Infect Dis Suppl 89: 3-62.
10. Aurelius E, Forsgren M, Skoldenberg B, Strannegard O (1993a). Persistent intrathecal immune activation in patients with herpes simplex encephalitis. J Infect Dis 168: 1248-1252.
11. Aurelius E, Johansson B, Sköldenberg B, Staland A, Forsgren M (1991). Rapid diagnosis of herpes simplex encephalitis by nested polymerase chain reaction assay of cerebrospinal fluid. Lancet 337: 189-192.
12. Aurelius E, Johansson B, Sköldenberg B, Forsgren M (1993b). Encephalitis in immunocompetent patients due to herpes simplex virus type 1 or 2 as determined by type-specific polymerase chain reaction and antibody assays of cerebrospinal fluid. J Med Virol 39: 179-186.
13. Bacellar H, Munoz A, Miller EN, Cohen BA, Besley D, Selnes OA, et al. (1994). Temporal trends in the incidence of HIV-1-related neurologic diseases: Multicenter AIDS Cohort Study, 1985-1992. Neurology 44: 1892-1900.
14. Bamborschke S, Wullen T, Huber M, Neveling M, Baldamus CA, Korn K, et al. (1992). Early diagnosis and successful treatment of acute cytomegalovirus encephalitis in renal transplant recipient. J Neurol 239: 205-208.
15. Baram TZ, Gonzalez Gomez I, Xie ZD, Yao D, Gilles FH, Nelson MD, Jr., et al. (1994). Subacute sclerosing panencephalitis in an infant: diagnostic role of viral genome analysis. Ann Neurol 36: 103-108.
16. Barany F (1991). The ligase chain reaction in a PCR world. Pcr Methods Appl 1: 5-16.
17. Baringer JR and Pisani P (1994). Herpes simplex virus genomes in human nervous system tissue analyzed by polymerase chain reaction. Ann Neurol 36: 823-829.
18. Berger JR and Concha M (1995). Progressive multifocal leukoencephalopathy: the evolution of a disease once considered rare. J NeuroVirol 1: 5-18.
19. Berger JR, Kaszovitz B, Post MJ, Dickinson G (1987). Progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection. A review of the literature with a report of sixteen cases. Ann Intern Med 107: 78-87.
20. Bock LC, Griffin LC, Latham JA, Vermaas EH, Toole JJ (1992). Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature 355: 564-566.
21. Boerman RH, Arnoldus EP, Raap AK, Bloem BR, Verhey M, van Gemert G, et al. (1989). Polymerase chain reaction and viral culture techniques to detect HSV in small volumes of cerebrospinal fluid; an experimental mouse encephalitis study. J Virol Methods 25: 189-197.
22. Bogdanovic G, Grandien M, Winblad B, Hammarin A-L, Nennesmo I, Dalians T (1994). Absences of JC virus DNA in CNS materials from patients with Alzheimer's disease and from elderly controls. In: Progress in Clinical Virology. Stockholm: pp 132.
23. Brown EG, Furesz J, Dimock K, Yarosh W, Contreras G (1991). Nucleotide sequence analysis of Urabe mumps vaccine strain that caused meningitis in vaccine recipients. Vaccine 9: 840-842.
24. Buckle GJ, Godec MS, Rubi JU, Tornatore C, Major EO, Gibbs CJJ, et al. (1992). Lack of JC viral genomic sequences in multiple sclerosis brain tissue by polymerase chain reaction. Ann Neurol 32: 829-831.
25. Cahill P, Foster K, Mahan DE (1991). Polymerase chain reaction and Q beta replicase amplification. Clin Chem 37: 1482-1485.
26. Caldas C, Bernicker E, Nogare AD, Luby JP (1994). Case report: transverse myelitis associated with Epstein-Barr virus infection. Am J Med Sci 307: 45-48.
27. Caserta MT, Hall CB, Schnabel K, McIntyre K, Long C, Costanzo M, et al. (1994). Neuroinvasion and persistence of human herpesvirus 6 in children. J Infect Dis 170: 1586-1589.
28. Cassinotti P, Schultze D, Schlageter P, Chevili S, Siegl G (1993). Persistent human parvovirus B19 infection following an acute infection with meningitis in an immunocompetent patient. Eur J Clin Microbiol Infect Dis 12: 701-704.
29. Chambers ST, Powell KF, Croxson MC, Krishnan S, Weir RP (1994). Demonstration of herpes simplex type 2 in the cerebrospinal fluid of two patients with recurrent lymphocytic meningitis. N Z Med J 107: 367-369.
30. Cinque P, Baldanti F, Vago L, Terreni MR, Lillo F, Furione M, et al. (1995). Ganciclovir therapy for cytomegalovirus (CMV) infection of the central nervous system in AIDS patients: monitoring by CMV DNA detection in cerebrospinal fluid. J Infect Dis 171: 1603-1606.
31. Cinque P, Brytting M, Vago L, Castagna A, Parravicini C, Zanchetta N, et al. (1993). Epstein-Barr virus DNA in cerebrospinal fluid from patients with AIDS-related primary lymphoma of the central nervous system. Lancet 342: 398-401.
32. Cinque P, Vago L, Bogdanovic G, Castagna A, D'Arminio Montforte A, Guarino M, et al. (1994). JC virus DNA in cerebrospinal fluid and central nervous system of AIDS subjects with progressive multifocal leukoencephalopathy (PML) and response to intrathecal ARA-C treatment. In: Progress in Clinical Virology. Stockholm: pp 55.
33. Cinque P, Vago L, Brytting M, Castagna A, Accordini A, Sundqvist VA, et al. (1992). Cytomegalovirus infection of the central nervous system in patients with AIDS: diagnosis by DNA amplification from cerebrospinal fluid. J Infect Dis 166: 1408-1411.
34. Clementi M, Bagnarelli P, Manzin A, Menzo S (1994). Competitive polymerase chain reaction and analysis of viral activity at the molecular level. Genet Anal Tech Appl 11: 1-6.
35. Clifford DB, Buller RS, Mohammed S, Robison L, Storch GA (1993). Use of polymerase chain reaction to demonstrate cytomegalovirus DNA in CSF of patients with human immunodeficiency virus infection. Neurology 43: 75-79.
36. Cohen BA, McArthur JC, Grohman S, Patterson B, Glass JD (1993). Neurologic prognosis of cytomegalovirus polyradiculomyelopathy in AIDS. Neurology 43: 493-499.
37. Cohen BA, Rowley AH, Long CM (1994). Herpes simplex type 2 in a patient with Mollaret's meningitis: demonstration by polymerase chain reaction. Ann Neurol 35: 112-116.
38. Cohrs R, Mahalingam R, Dueland AN, Wolf W, Wellish M, Gilden DH (1992). Restricted transcription of varicella-zoster virus in latently infected human trigeminal and thoracic ganglia. J Infect Dis 166 [Suppl 1]: S24-S29.
39. Compton J (1991). Nucleic acid sequence-based amplification. Nature 350: 91-92.
40. Darnell RB (1993). The polymerase chain reaction: application to nervous system disease. Ann Neurol 34: 513-523.
41. DeAnda A, Jr., Coutre SE, Moon MR, Vial CM, Griffin LC, Law VS, et al. (1994). Pilot study of the efficacy of a thrombin inhibitor for use during cardiopulmonary bypass. Ann Thorac Surg 58: 344-350.
42. Demaerel P, Wilms G, Robberecht W, Johannik K, Van Hecke P, Carton H, et al (1992). MRI of herpes simplex encephalitis. Neuroradiology 34: 490-493.
43. Dennett C, Klapper PE, Cleator GM, Lewis AG (1991). CSF pretreatment and the diagnosis of herpes encephalitis using the polymerase chain reaction. J Virol Methods 34: 101-104.
44. Dhib Jalbut S, McFarland HF, Mingioli ES, Sever JL, McFarlin DE (1988). Humoral and cellular immune responses to matrix protein of measles virus in subacute sclerosing panencephalitis. J Virol 62: 2483-2489.
45. Di Stefano M, Sabri F, Leitner T, Svennerholm B, Hagberg L, Norkrans G, et al. (1995). Reverse transcriptase sequence of paired isolates of cerebrospinal fluid and blood from patients infected with human immunodeficiency virus type 1 during zidovudine treatment. J Clin Microbiol 33: 352-355.
46. Dix RD, Bredesen DE, Erlich KS, Mills J (1985). Recovery of herpesviruses from cerebrospinal fluid of immunodeficient homosexual men. Ann Neurol 18: 611-614.
47. Dörries R, Liebert UG, ter Meulen V (1988). Comparative analysis of virus-specific antibodies and immunoglobulins in serum and cerebrospinal fluid of subacute measles virus-induced encephalomyelitis (SAME) in rats and subacute sclerosing panencephalitis (SSPE). J Neuroimmunol 19: 339-352.
48. Drummond CW, Eglin RP, Esiri MM (1994). Herpes simplex virus encephalitis in a mouse model: PCR evidence for CNS latency following acute infection. J Neurol Sci 127: 159-163.
49. Dwyer DE and Saksena N (1992). Failure of ultra-violet irradiation and autoclaving to eliminate PCR contamination. Mol Cell Probes 6: 87-88.
50. Echevarria JM, Casas I, Tenorio A, de Ory F, Martinez Martin P (1994). Detection of varicella-zoster virus-specific DNA sequences in cerebrospinal fluid from , patients with acute aseptic meningitis and no cutaneous lesions. J Med Virol 43: 331-335.
51. Editorial (1992). Brain biopsy for intracranial mass lesions in AIDS. Lancet 340: 1135.
52. Ellington AD and Szostak JW (1990). In vitro selection of RNA molecules that bind specific ligands. Nature 346: 818-822.
53. Elsner C and Dörries K (1992). Evidence of human polyomavirus BK and JC infection in normal brain tissue. Virology 191: 72-80.
54. Erlich HA, Gelfand D, Sninsky JJ (1991). Recent advances in the polymerase chain reaction. Science 252: 1643-1651.
55. Fillet AM, Katlama C, Visse B, Camilleri S, Rogeaux O, Huraux JM (1993). Human CMV infection of the CNS: concordance between PCR detection in CSF and pathological examination. Aids 7: 1016-1018.
56. Forsey T, Mawn JA, Yates PJ, Bentley ML, Minor PD (1990). Differentiation of vaccine and wild mumps viruses using the polymerase chain reaction and dideoxynucleotide sequencing. J Gen Virol 71: 987-990.
57. Fuller GN, Jacobs JM, Guiloff RJ (1993). Nature and incidence of peripheral nerve syndromes in HIV infection. J Neurol Neurosurg Psychiatry 56: 372-381.
58. Gibson PE, Knowles WA, Hand JF, Brown DW (1993). Detection of JC virus DNA in the cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy. J Med Virol 39: 278-281.
59. Gilden DH, Beinlich BR, Rubinstein EM, Stommel E, Swenson R, Rubinstein D, et al. (1994). Varicellazoster virus myelitis: an expanding spectrum. Neurology 44: 1818-1823.
60. Gilden DH, Dueland AN, Devlin ME, Mahalingam R, Cohrs R (1992). Varicella-zoster virus reactivation without rash. J Infect Dis 166 [Suppl 1]: S30-S34.
61. Glimaker M, Johansson B, Olcen P, Ehrnst A, Forsgren M (1993). Detection of enteroviral RNA by polymerase chain reaction in cerebrospinal fluid from patients with aseptic meningitis. Scand J Infect Dis 25: 547-557.
62. Godec MS, Asher DM, Murray RS, Shin ML, Greenham LW, Gibbs CJ, Jr., et al. (1992). Absence of measles, mumps and rubella viral genomic sequences from multiple sclerosis brain tissue by polymerase chain reaction. Ann Neurol 32: 401-404.
63. Goswami KK, Miller RF, Harrison MJ, Hamel DJ, Daniels RS, Tedder RS (1991). Expression of HIV-1 in the cerebrospinal fluid detected by the polymerase chain reaction and its correlation with central nervous system disease. Aids 5: 797-803.
64. Gozlan J, el Amrani M, Baudrimont M, Costagliola D, Salord JM, Duvivier C, et al. (1995). A prospective evaluation of clinical criteria and polymerase chain reaction assay of cerebrospinal fluid for the diagnosis of cytomegalovirus-related neurological diseases during AIDS. Aids 9: 253-260.
65. Gozlan J, Salord JM, Roullet E, Baudrimont M, Caburet F, Picard O, et al. (1992). Rapid detection of cytomegalovirus DNA in cerebrospinal fluid of AIDS patients with neurologic disorders. J Infect Dis 166: 1416-1421.
66. Grant AD, Fox JD, Brink NS, Miller RF (1993). Detection of varicella-zoster virus DNA using the polymerase chain reaction in an immunocompromised patient with transverse myelitis secondary to herpes zoster. Genitourin Med 69: 273-275.
67. Gray F, Gherardi R, Scaravilli F (1988). The neuropathology of the acquired immune deficiency syndrome (AIDS). A review. Brain, 111: 245-266.
68. Gressens P, Langston C, Martin JR (1994). In situ PCR localization of herpes simplex virus DNA sequences in disseminated neonatal herpes encephalitis. J Neuropathol Exp Neurol 53: 469-482.
69. Griffin DE, Wesselingh SL, McArthur JC (1994). Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia. Ann Neurol 35: 592-597.
70. Grimprel E, Sanchez PJ, Wendel GD, Burstain JM, McCracken GJ, Radolf JD, et al. (1991). Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera, and cerebrospinal fluid. J Clin Microbiol 29: 1711-1718.
71. Guffond T, Dewilde A, Lobert PE, Caparros Lefebvre D, Hober D, Wattre P (1994). Significance and clinical relevance of the detection of herpes simplex virus DNA by the polymerase chain reaction in cerebrospinal fluid from patients with presumed encephalitis. Clin Infect Dis 18: 744-749.
72. Halonen P, Rocha E, Hierholzer J, Holloway B, Hyypia T, Hurskainen P, et al. (1995). Detection of enteroviruses and rhinoviruses in clinical specimens by PCR and liquid-phase hybridization. J Clin Microbiol 33: 648-653.
73. Hara H, Morita M, Iwaki T, Hatae T, Itoyama Y, Kitamoto T, et al. (1994). Detection of human T lymphotrophic virus type I (HTLV-1) proviral DNA and analysis of T cell receptor V beta CDR3 sequences in spinal cord lesions of HTLV-1-associated myelopathy/tropical spastic paraparesis. J Exp Med 180: 831-839.
74. Heide W, Kömpf D, Reusche E, Bodemer M, Weber T (1995). Failure of cytarabine/interferon therapy in progressive multifocal leukoencephalopathy. Ann Neurol 37: 412-413.
75. Henson J, Rosenblum M, Armstrong D, Furneaux H (1991). Amplification of JC virus DNA from brain and cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy. Neurology 41: 1967-1971.
76. Herndon RM (1996). Herpesviruses in multiple sclerosis. Arch Neural 53: 123-124.
77. Hjelle B, Appenzeller O, Mills R, Alexander S, Torrez Martinez N, Jahnke R, et al. (1992). Chronic neurodegenerative disease associated with HTLV-II infection. Lancet 339: 645-646.
78. Holland NR, Power C, Mathews VP, Glass JD, Forman M, McArthur JC (1994). Cytomegalovirus encephalitis in acquired immunodeficiency syndrome (AIDS). Neurology 44: 507-514.
79. Holman RC, Janssen RS, Buehler JW, Zelasky MT, Hooper WC (1991). Epidemiology of progressive multifocal leukoencephalopathy in the United States: analysis of national mortality and AIDS surveillance data. Neurology 41: 1733-1736.
80. Howe DK, Vodkin MH, Novak RJ, Shope RE, McLaughlin GL (1992). Use of the polymerase chain reaction for the sensitive detection of St. Louis encephalitis viral RNA. J Virol Methods 36: 101-110.
81. Imai S, Usui N, Sugiura M, Osato T, Sato T, Tsutsumi H, et al. (1993). Epstein-Barr virus genomic sequences and specific antibodies in cerebrospinal fluid in children with neurologic complications of acute and reactivated EBV infections. J Med Viral 40: 278-284.
82. Janssen RS, Cornblath DR, Epstein LG, McArthur J, Price RW (1989). Human immunodeficiency virus (HIV) infection and the nervous system: report from the American Academy of Neurology AIDS Task Force. Neurology 39: 119-122.
83. Kammerer U, Kunkel B, Korn K (1994). Nested PCR for specific detection and rapid identification of human picornaviruses. J Clin Microbiol 32: 285-291.
84. Kemp DJ, Smith DB, Foote SJ, Samaras N, Peterson MG (1989). Colorimetric detection of specific DNA segments amplified by polymerase chain reactions. Proc Natl Acad Sci USA 86: 2423-2427.
85. Kimura H, Aso K, Kuzushima K, Hanada N, Shibata M, Morishima T (1992). Relapse of herpes simplex encephalitis in children. Pediatrics 89: 891-894.
86. Kindley AD, Harris F, Bush GH (1978). Herpes-simplex infection presenting as brainstem encephalitis. Lancet 1: 212-213.
87. Kinoshita T, Tsujimoto A, Shimotohno K (1991). Sequence variations in LTR and env regions of HTLV-I do not discriminate between the virus from patients with HTLV-I-associated myelopathy and adult T-cell leukemia. Int J Cancer 47: 491-495.
88. Kira J, Koyanagi Y, Yamada T, Itoyama Y, Tateishi J, Akizuki S, et al. (1994). Sequence heterogeneity of HTLV-I proviral DNA in the central nervous system of patients with HTLV-I-associated myelopathy. Ann Neurol 36: 149-156.
89. Klapper PE, Cleator GM, Dennett C, Lewis AG (1990). Diagnosis of herpes encephalitis via Southern blotting of cerebrospinal fluid DNA amplified by polymerase chain reaction. J Med Virol 32: 261-264.
90. Klapper PE, Cleator GM, Longson M (1984). Mild forms of herpes encephalitis. J Neurol Neurosurg Psychiatry 47: 1247-1250.
91. Kohyama J, Kajiwara M, Shimohira M, Iwakawa Y, Okawa H (1994). Human cytomegalovirus DNA in cerebrospinal fluid. Arch Dis Child 71: 414-418.
92. Kondo K, Nagafuji H, Hata A, Tomomori C, Yamanishi K (1993). Association of human herpesvirus 6 infection of the central nervous system with recurrence of febrile convulsions. J Infect Dis 167: 1197-1200.
93. Koskiniemi M, Rautonen J, Lehtokoski Lehtiniemi E, Vaheri A (1991). Epidemiology of encephalitis in children: a 20-year survey. Ann Neurol 29: 492-497.
94. Kuijper JL, Wiren KM, Mathies LD, Gray CL, Hagen FS (1992). Functional cloning vectors for use in directional cDNA cloning using cohesive ends produced with T4 DNA polymerase. Gene 112: 147-155.
95. Kure K, Llena JF, Lyman WD, Soeiro R, Weidenheim KM, Hirano A, et al. (1991). Human immunodeficiency virus-1 infection of the nervous system: an autopsy study of 268 adult, pediatric, and fetal brains. Hum Pathol 22: 700-710.
96. Kwok S and Higuchi R (1989). Avoiding false positives with PCR. Nature 339: 237-238.
97. Kyllerman MG, Herner S, Bergstrom TB, Ekholm SE (1993). PCR diagnosis of primary herpesvirus type I in poliomyelitis-like paralysis and respiratory tract disease. Pediatr Neurol 9: 227-229.
98. Lakeman FD and Whitley RJ (1995). Diagnosis of herpes simplex encephalitis: application of polymerase chain reaction to cerebrospinal fluid from brain-biopsied patients and correlation with disease. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. J Infect Dis 171: 857-863.
99. Landgren M, Kyllerman M, Bergstrom T, Dotevall L, Ljungstrom L, Ricksten A (1994). Diagnosis of Epstein-Barr virus-induced central nervous system infections by DNA amplification from cerebrospinal fluid. Ann Neurol 35: 631-635.
100. Lehky TJ, Fox CH, Koenig S, Levin MC, Flerlage N, Izumo S, et al. (1995). Detection of human T-lymphotropic virus type I (HTLV-I) tax RNA in the central nervous system of HTLV-I-associated myelopathy/tropical spastic paraparesis patients by in situ hybridization. Ann Neurol 37: 167-175.
101. Liedtke W, Opalka B, Zimmermann CW, Lignitz E (1993). Age distribution of latent herpes simplex virus 1 and varicella-zoster virus genome in human nervous tissue. J Neurol Sci 116: 6-11.
102. Lisitsyn N, Lisitsyn N, Wigler M (1993). Cloning the differences between two complex genomes. Science 259: 946-951.
103. Lizardi PM, Guerra CE, Lomeli H, Tussie-Luna I, Kramer FR (1988). Exponential amplification of recombinant-RNA hybridization probes. Biotechnology 6: 1197-1202.
104. Longo MC, Berninger MS, Hartley JL (1990). Use of uracil DNA glycosylase to control carry-over contamination in polymerase chain reactions. Gene 93: 125-128.
105. Major EO, Amemiya K, Tornatore CS, Houff SA, Berger JR (1992). Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clin Microbiol Rev 5: 49-73.
106. Matsuzono Y, Narita M, Ishiguro N, Togashi T (1994). Detection of measles virus from clinical samples using the polymerase chain reaction. Arch Pediatr Adolesc Med 148: 289-293.
107. McCutchan JA (1995). Cytomegalovirus infections of the nervous system in patients with AIDS. Clin Infect Dis 20: 747-754.
108. McGuire D, Barhite S, Hollander H, Miles M (1995). JC virus DNA in cerebrospinal fluid of human immunodeficiency virus-infected patients: predictive value for progressive multifocal leukoencephalopathy. Ann Neurol 37: 395-399.
109. Menzo S, Manzin A, Bagnarelli P, Varaldo PE, Grandi G, Giuliano G, et al. (1992). Lack of detectable human T-cell lymphotropic virus type I sequences in samples from multiple sclerosis patients. J Med Virol 36: 155-161.
110. Merelli E, Sola P, Marasca R, Salati R, Torelli G (1993). Failure to detect genomic material of HTLV-I or HTLV-II in mononuclear cells of Italian patients with multiple sclerosis and chronic progressive myelopathy. Eur Neurol 33: 23-26.
111. Mertens G, Leven M, Ursi D, Pattyn SR, Martin JJ, Parizel PM (1993). Detection of herpes simplex virus in the cerebrospinal fluid of patients with encephalitis using the polymerase chain reaction. J Neurol Sci 118: 213-216.
112. Miller E, Goldacre M, Pugh S, Colville A, Farrington P, Flower A, et al. (1993). Risk of aseptic meningitis after measles, mumps and rubella vaccine in UK children. Lancet 341: 979-982.
113. Moret H, Guichard M, Matherson S, Katlama C, Sazdovitch V, Huraux J-M, et al. (1993). Virological diagnosis of progressive multifocal leukoencephalopathy: detection of JC virus DNA in cerebrospinal fluid and brain tissue of AIDS patients. J Clin Microbiol 31: 3310-3313.
114. Morgello S, Petito CK, Mouradian JA (1990). Central nervous system lymphoma in the acquired immunodeficiency syndrome. Clin Neuropathol 9: 205-215.
115. Muir P, Nicholson F, Jhetam M, Neogi S, Banatvala JE (1993). Rapid diagnosis of enterovirus infection by magnetic bead extraction and polymerase chain reaction detection of enterovirus RNA in clinical specimens. J Clin Microbiol 31: 31-38.
116. Mullis KB and Faloona FA (1987). Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol 155: 335-350.
117. Mustafa MM, Weitman SD, Winick NJ, Bellini WJ, Timmons CF, Siegel JD (1993). Subacute measles encephalitis in the young immunocompromised host: report of two cases diagnosed by polymerase chain reaction and treated with ribavirin and review of the literature. Clin Infect Dis 16: 654-660.
118. Nicholson F, Meetoo G, Aiyar S, Banatvala JE, Muir P (1994). Detection of enterovirus RNA in clinical samples by nested polymerase chain reaction for rapid diagnosis of enterovirus infection. J Virol Methods 48: 155-166.
119. Okumura A and Ichikawa T (1993). Aseptic meningitis caused by human parvovirus B19. Arch Dis Child 68: 784-785.
120. Padgett BL, Walker DL, Zu Rhein GM, Eckroade RJ, Dessel BH (1971). Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet i: 1257-1260.
121. Pao CC, Hor JJ, Tsai PL, Horng MY (1993). Inhibition of in vitro enzymatic DNA amplification reaction by ultra-violet light irradiation. Mol Cell Probes 7: 217-219.
122. Pedersen C, Thomsen C, Arlien SP, Praestholm J, Kjaer L, Boesen F, et al. (1991). Central nervous system involvement in human immunodeficiency virus disease. A prospective study including neurological examination, computerized tomography, and magnetic resonance imaging. Dan Med Bull 38: 374-379.
123. Perrons CJ, Fox JD, Miller RF, Lucas SB, Tedder RS (1994). Molecular analysis of polyomaviruses associated with neurological disease in immunosuppressed patients. In: Neuroscience of HIV Infection; Basic and Clinical Frontiers. Vancouver.
124. Petito CK and Morgello S (1990). AIDS and the central nervous sytem. Monogr Pathol 1990: 130-138.
125. Puchhammer-Stoeckl E, Heinz FX, Kunz C (1993). Evaluation of 3 nonradioactive DNA detection systems for identification of herpes simplex DNA amplified from cerebrospinal fluid. J Virol Methods 43: 257-266.
126. Robb L and Butt W (1989). Brain stem encephalitis due to herpes simplex virus. Aust Paediatr J 25: 246-247.
127. Rodriguez C, Conticchio LM, Morgello S (1992). Is JC virus latent in brain? A study utilizing polymerase chain reaction. J Neuropathol Exp Neural 51: 372.
128. Rozenberg F and Lebon P (1991). Amplification and characterization of herpesvirus DNA in cerebrospinal fluid from patients with acute encephalitis. J Clin Microbiol 29: 2412-2417.
129. Ruzicka V, Marz W, Russ A, Gross W (1993). Immuno-PCR with a commercially available avidin system. Science 260: 698-699.
130. Saiki RK, Gelfand DH, Stoffel S, Scharf SJ, Higuchi R, Horn GT, et al. (1988). Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239: 487-491.
131. Sanna PP, Weiss F, Samson ME, Bloom FE, Pich EM (1995). Rapid induction of tumor necrosis factor alpha in the cerebrospinal fluid after intracerebroventricular injection of lipopolysaccharide revealed by a sensitive capture immuno-PCR assay. Proc Natl Acad Sci USA 92: 272-275.
132. Sano T, Smith CL, Cantor CR (1992). Immuno-PCR: very sensitive antigen detection by means of specific antibody-DNA conjugates. Science 258: 120-122.
133. Sawyer MH, Holland D, Aintablian N, Connor JD, Keyser EF, Waecker N, Jr. (1994). Diagnosis of enteroviral central nervous system infection by polymerase chain reaction during a large community outbreak. Pediatr Infect Dis J 13: 177-182.
134. Schlesinger Y, Buller RS, Brunstrom JE, Moran CJ, Storch GA (1995). Expanded spectrum of herpes simplex encephalitis in childhood. J Pediatr 126: 234-241.
135. Schutt M, Lakeman FD, Whitley RJ (1985). Psychosis and herpes simplex encephalitis. South Med J 78: 1347-1350.
136. Schmid P, Conrad A, Syndulko K, Singer EJ, Handley D, Li X, et al. (1994). Quantifying HIV-1 proviral DNA using the polymerase chain reaction on cerebrospinal fluid and blood of seropositive individuals with and without neurologic abnormalities. J Acquir Immune Defic Syndr 7: 777-788.
137. Schmidbauer M, Podreka I, Wimberger D, Oder W, Koch G, Wenger S, et al. (1991). SPECT and MR imaging in herpes simplex encephalitis. J Comput Assist Tomogr 15: 811-815.
138. Seno A, Tada J, Matsuura H, Arata J, Isomura H, Kitamura T, et al. (1994). Congenital rubella syndrome with rubella virus-associated generalized brownish macules, indurated erythemas, papules, and pigmentation. J Dermatol 21: 323-328.
139. Shaunak S, Albright RE, Klotman ME, Henry SC, Bartlett JA, Hamilton JO (1990). Amplification of HIV-1 provirus from cerebrospinal fluid and its correlation with neurologic disease. J Infect Dis 161: 1068-1072.
140. Shimizu C, Shimizu H, Mitsuda T, Tsukuda M, Ichikawa S, Yokota S (1994). One-step determination of herpes simplex virus types I and II by polymerase chain reaction. Mol Cell Probes 8: 193-198.
141. Shoji H, Honda Y, Murai I, Sato Y, Oizumi K, Hondo R (1992). Detection of varicella-zoster virus DNA by polymerase chain reaction in cerebrospinal fluid of patients with herpes zoster meningitis. J Neurol 239: 69-70.
142. Sonnerborg A, Saaf J, Alexius B, Strannegard O, Wahlund LO, Wetterberg L (1990). Quantitative detection of brain aberrations in human immunodeficiency virus type 1-infected individuals by magnetic resonance imaging. J Infect Dis 162: 1245-1251.
143. Spector SA, Hsia K, Pratt D, Lathey J, McCutchan JA, Alcaraz JE, et al. (1993). Virologic markers of human immunodeficiency virus type 1 in cerebrospinal fluid. The HW Neurobehavioral Research Center Group. J Infect Dis 168: 68-74.
144. Srikanth S, Ravi V, Poornima KS, Shetty KT, Gangadhar BN, Janakiramaiah N (1994). Viral antibodies in recent onset, nonorganic psychoses: correspondence with symptomatic severity. Biol Psychiatry 36: 517-521.
145. Steuler H, Storch-Hagenlocher B, Wildemann B (1992). Distinct populations of human immunodeficiency virus type 1 in blood and cerebrospinal fluid. Aids Res Hum Retroviruses 8: 53-59.
146. Svenningsson A, Lycke J, Svennerholm B, Gronowitz S, Andersen O (1992). No evidence for spumavirus or oncovirus infection in relapsing-remitting multiple sclerosis. Ann Neurol 32: 711-714.
147. Tedder DG, Ashley R, Tyler KL, Levin MJ (1994). Herpes simplex virus infection as a cause of benign recurrent lymphocytic meningitis. Ann Intern Med 121: 334-338.
148. Tornatore C, Berger JR, Houff SA, Curfman B, Meyers K, Winfield D, et al. (1992). Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy. Ann Neurol 31: 454-462.
149. Troendle-Atkins J, Demmler GJ, Buffone GJ (1993). Rapid diagnosis of herpes simplex virus encephalitis by using the polymerase chain reaction. J Pediatr 123: 376-380.
150. Troendle-Atkins J, Demmler GJ, Williamson WD, McDonald JM, Istas AS, Buffone GJ (1994). Polymerase chain reaction to detect cytomegalovirus DNA in the cerebrospinal fluid of neonates with congenital infection. J Infect Dis 169: 1334-1337.
151. Tsutsumi H, Kamazaki H, Nakata S, Nagao, Chiba S, Imai S, et al. (1994). Sequential development of acute meningoencephalitis and transverse myelitis caused by Epstein-Barr virus during infectious mononucleosis. Pediatr Infect Dis J 13: 665-667.
152. Walker DL (1985). Progressive multifocal leukoencephalopathy. In: Vinken P, Bruyn GW, Klawans HL (eds): 'Handbook of clinical neurology, Demyelinating Diseases', edn. vol 47 (3), Amsterdam: Elsevier Science Publishers, pp 503-524.
153. Walker DL and Frisque RJ (1986). The biology and Molecular Biology of JC Virus. In: Salzman NP (eds): "The Papovaviridae. The Polyomaviruses". Vol 1, New York: Plenum Press, pp 327-377.
154. Watanabe H, Nakamura T, Nagasato K, Shirabe S, Ohishi K, Ichinose K, et al. (1995). Exaggerated messenger RNA expression of inflammatory cytokines in human T-cell lymphotropic virus type 1-associated myelopathy. Arch Neurol 52: 276-280.
155. Weber HC, Schoeman JF, Nowitz A, Becker ML (1994a). Case report: psychosis associated with hepatitis B. J Med Virol 44: 5-8.
156. Weber T, Beck R, Stark E, Gerhards J, Korn K, Haas J, et al. (1994b). Comparative analysis of iantrathecal antibody synthesis and DNA amplification for the diagnosis of cytomegalovirus infection of the central nervous system in AIDS patients. J Neurol 241: 407-414.
157. Weber T, Turner RW, Frye S, Luke W, Kretzschmar HA, Lüer W, et al. (1994e). Progressive multifocal leukoencephalopathy diagnosed by amplification of JC virus-specific DNA from cerebrospinal fluid. AIDS 8: 49-57.
158. Weber T, Turner RW, Frye S, Ruf B, Haas J, Schielke E, et al. (1994d). Specific diagnosis of progressive multifocal leukoencephalopathy by polymerase chain reaction. J Infect Dis 169: 1138-1141.
159. Webster AD, Rotbart HA, Warner T, Rudge P, Hyman N (1993). Diagnosis of enterovirus brain disease in hypogammaglobulinemic patients by polymerase chain reaction. Clin Infect Dis 17: 657-661.
160. White FA, Ishaq M, Stoner GL, Frisque RJ (1992). JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy. J Virol 66: 5726-5734.
161. Whitley RJ, Soong S-J, Dolin R, Galasso GJ, Ch'ien LT, Alford CA, et al. (1977). Adenine arabinoside therapy of biopsy-proved herpes simplex encephalitis. National Institute of Allergy and Infectious Diseases collaborative antiviral study. N Engl J Med 297: 289-294.
162. Wildemann B, Haas J, Ehrhart K, Wagner H, Lynen N, Storch-Hagenlocher B (1993). In vivo comparison of zidovudine resistance mutations in blood and CSF of HIV-1-infected patients. Neurology 43: 2659-2663.
163. Wolcott MJ (1992). Advances in nucleic acid-based detection methods. Clin Microbiol Rev 5: 370-386.
164. Wolf DG and Spector SA (1992). Diagnosis of human cytomegalovirus central nervous system disease in AIDS patients by DNA amplification from cerebrospinal fluid. J Infect Dis 166: 1412-1415.
165. Yamamoto LJ, Tedder DG, Ashley R, Levin MJ (1991). Herpes simplex virus type 1 DNA in cerebrospinal fluid of a patient with Mollaret's meningitis. N Engl J Med 325: 1082-1085.
166. Yoshikawa T, Nakashima T, Suga S, Asano Y, Yazaki T, Kimura H, et al. (1992). Human herpesvirus-6 DNA in cerebrospinal fluid of a child with exanthem subitum and meningoencephalitis. Pediatrics 89: 888-890.
167. Zabernigg A, Maier H, Thaler J, Gattringer C (1994). Lateonset fatal
168. Zhou H, Fisher RJ, Papas TS (1993). Universal immunoPCR for ultra-sensitive target protein detection. Nucleic Acids Res 21: 6038-6039.