Differential effect of the activation of protein kinase A on the protein synthesis and secretion in the T-helper 2 cell line D10.G4.1

Scandinavian Journal of Immunology

Volumn 44, Issue 2, 1996, Pages 150-156

  Teschendorf, C ^a,b   Trenn, G ^a   Hoffkes H G ^a   Brittinger, G ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; INTERLEUKIN 10; INTERLEUKIN 4; MESSENGER RNA; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C;

ANIMAL CELL; ARTICLE; CELL LINE; ENZYME LINKED IMMUNOSORBENT ASSAY; HELPER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; T LYMPHOCYTE;

EID: 0030018065     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1996.d01-295.x     Document Type: Article

References (29)

1. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986;136:2348-57.
2. Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-73.
3. Fishman MA, Perelson AS. Th1/Th2 cross regulation. J Theor Biol 1994;170:25-56.
4. Fiorentino DF, Bond MW, Mosmann TR. Two types of T helper cell IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989;170:2081-95.
5. Sher A, Jazzinelli RT, Oswald IP et al. Role of T cell derived cytokines in the down regulation of immune responses in parasitic and retroviral infection. Immunol Rev 1992;127:181-204.
6. Chakkalath HR, Titus RG. Leishmania major-parasitized macrophages augment Th2-type T cell activation. J Immunol 1994;153:4378-87.
7. Finkelmann FD, Madden KB, Cheever AW et al. Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites [see comments]. J Exp Med 1994;179:1563-72.
8. Betz M, Fox BS. Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. J Immunol 1991;146:108-13.
9. Kroenke MW, Leonard WJ, Depper JM et al. Cyclosporin A inhibits T cell growth factor gene expression at the level of mRNA transcription. Proc Natl Acad Sci 1984;81:5214-18.
10. Gajewski TF, Schell SR, Fitch FW. Evidence implicating utilisation of different T cell receptor-associated signalling pathways by TH1 and TH2 clones. J Immunol 1990;144:4110-20.
11. Staerz UD, Kanagawa O, Bevan MJ. Hybrid antibodies can target sites for attack by T cells. Nature 1985;314:628-31.
12. Kaye J, Porcelli S, Tite J, Jones B, Janeway CA. Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells. J Exp Med 1983;158:836-56.
13. Staerz UD, Rammensee HG, Benedetto JD, Bevan MJ. Characterisation of a murine monoclonal antibody specific for an allotypic determination on T cell antigen receptor. J Immunol 1985;134:3994-4000.
14. Leo O, Foo M, Sachs DM, Samelson LE, Bluestone JA. Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc Natl Acad Sci USA 1987;84:1374-8.
15. Ohara J, Paul WE. Production of a monoclonal antibody to and molecular characterisation of B cell stimulatory factor-1. Nature 1985;315:333-6.
16. Trenn G, Sykora J, Teschendorf Ch, Taffs R, Brittinger G, Sitkovsky MV. Detection of distinct sets of newly synthesized polypeptides in supernatants of TCR-triggered T cell clones. J Immunol Meth 1993;161:41-57.
17. Schägger H, von Jagow G. Tricine-sodium dodecyl sulphate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 1987;166:368-79.
18. Trenn G, Sykora J, Michel MC, Brittinger G. Functional and biochemical characterisation of a calcium-ionophore-induced state of unresponsiveness in a cytolytic T cell clone. J Immunol 1992;148:1338-46.
19. Takayama H, Trenn G, Sitkovsky MV. Locus of inhibitory action of cAMP-dependent protein kinase in the antigen receptor-triggered cytotoxic T lymphocyte activation pathway. J Biol Chem 1988;263:2330-6.
20. Uppenkamp M, Gana Dresen I, Becher R, Raffeld M, Meusers P. Molecular analysis of an ataxia telangiectasia T cell clone with a chromosomal translocation t(14;18)-Evidence for a breakpoint in the T cell receptor δ-chain gene. Leukaemia Res 1992;16:681-91.
21. Hsu D-H, de Waal Malefyt R, Fiorentino DF et al. Expression of interleukin 10 activity by Epstein Barr virus protein BCRF1. Science 1990;250:830-2.
22. O'Shea JJ, Urdahl KB, Luong HT, Chused TM, Samelson LE, Klausner RD. Aluminium fluoride induces phosphotidylinositol turnover, elevation of cytoplasmatic free calcium, and phosphorylation of the T cell antigen receptor in murine T cells. J Immunol 1987;139:3463-9.
23. Nowak TJ, Rothenberg EV. cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells. Proc Natl Acad Sci USA 1990;87:9353-7.
24. Li T-K, Fox BS. Effect of prostaglandin E2 (PGE2) on IL-3/ granulocyte-macrophage colony-stimulating factor by T helper cells. J Immunol 1993;150:1680-90.
25. Pouw-Kraan van der T, Kooten van C, Rensink I, Aarden L. Interleukin (IL)-4 production by human T cells: differential regulation of IL-4 vs. IL-2 production. Eur J Immunol 1992; 22:1237-41.
26. Snijdewint FGM, Pawel K, Wierenga EA, Bos JD, Kapsenberg ML. Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J Immunol 1993; 150:5321-9.
27. Naora H, Altin JG, Young IG. TCR-dependent and -independent signalling mechanisms differentially regulate lymphokine gene expression in the murine T helper clone D10.G4.1. J Immunol 1994;152:5691-702.
28. Lee HJ, Koyano-Nakagawa N, Naito Y et al. cAMP activates the IL-5 promoter synergistically with phorbol ester through the signalling pathway involving protein kinase A in mouse thymoma line EL-4. J Immunol 1993;151:6135-42.
29. Seder RA, Paul WE. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu Rev Immunol 1994;12: 635-73.