Effects of phosphate-modified analogs of adenosine 5'-diphosphate and adenosine 5'-triphosphate at P(2T)-purinoceptors mediating human platelet activation by ADP

Drug Development Research

Volumn 37, Issue 4, 1996, Pages 212-222

  Cusack, Noel J ^a   Pettey, Caroline J ^b  

^a ADERIS Pharmaceuticals Inc   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Adenylate cyclase; ADP analogs; ATP analogs; Cyclic AMP; Human blood platelets; P(2T) purinoceptor agonists; P(2T) purinoceptor antagonists; P(2T) purinoceptors

Indexed keywords

2 METHYLTHIO BETA,GAMMA METHYLENEADENOSINE TRIPHOSPHATE; ADENYLATE CYCLASE; ADENYLYLIMIDODIPHOSPHATE; ANTITHROMBOCYTIC AGENT; BETA,GAMMA METHYLENEADENOSINE TRIPHOSPHATE; PROSTAGLANDIN E1; PURINE P2 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; DRUG EFFECT; DRUG POTENCY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

EID: 0030017078     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199604)37:4<212::AID-DDR3>3.0.CO;2-O     Document Type: Article

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