Microtubule-disrupting agents inhibit nitric oxide production in murine peritoneal macrophages stimulated with lipopolysaccharide or paclitaxel (taxol)

Infection and Immunity

Volumn 64, Issue 8, 1996, Pages 3379-3384

  Kirikae, Teruo ^a   Kirikae, Fumiko ^a   Oghiso, Yoichi ^b   Nakano, Masayasu ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; COLCHICINE; LUMICOLCHICINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NOCODAZOLE; PACLITAXEL; PODOPHYLLOTOXIN; VINBLASTINE;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; ENZYME ACTIVITY; MICROTUBULE; MITOSIS; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSCRIPTION;

EID: 0030016905     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.8.3379-3384.1996     Document Type: Article

References (30)

1. Bogdan, C., and A. Ding. 1992. Taxol, a microtubule-stabilizing antineoplastic agent, induces expression of tumor necrosis factor a and interleukin-1 in macrophages. J. Leukocyte Biol. 52:119-121.
2. Burns, R. G. 1992. Analysis of the colchicine-binding site of β-tubulin. FEBS Lett. 297:205-208.
3. Ding, A., E. Sanchez, M. Tancinco, and C. Nathan. 1992. Interactions of bacterial lipopolysaccharide with microtubule proteins. J. Immunol. 148: 2853-2858.
4. Ding, A. H., F. Porteu, E. Sanchez, and C. F. Nathan. 1990 Shared actions of endotoxin and taxol on TNF receptors and TNF release. Science 248:370-372.
5. Ding, A. H., F. Porteu, E. Sanchez, and C. F. Nathan. 1990. Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents. J. Exp. Med. 171:715-727.
6. 15N]nitrate in biological fluids. Anal. Biochem. 126:131-138.
7. Kirikae, F., T. Kirikae, N. Qureshi, K. Takayama, D. C. Morrison, and M. Nakano. 1995. CD14 is not involved in Rhodobacter sphaeroides diphosphoryl lipid A inhibition of tumor necrosis factor alpha and nitric oxide induction by taxol in murine macrophages. Infect. Immun. 63:486-497.
8. Kirikae, T., F. U. Schade, F. Kirikae, E. T. Rietchel, and D. C. Morrison. 1993. Isolation of a macrophage-like cell line defective in binding of lipopolysaccharide. Influence of serum and lipopolysaccharide chain length on macrophage activation. J. Immunol. 151:2742-2752.
9. Kumar, N. 1981. Taxol-induced polymerization of purified tubulin. J. Biol. Chem. 256:10435-10441.
10. Lyons, C. R., G. J. Orloff, and J. M. Cunningham. 1992. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267:6370-6374.
11. Manfredi, J. J., J. Parness, and S. B. Horwitz. 1982. Taxol binds to cellular microtubles. J. Cell Biol. 94:688-696.
12. Manthey, C. L., P. Y. Perera, N. Qureshi, P. L. Stütz, T. A. Hamilton, and S. N. Vogel. 1993. Modulation of lipopolysaccharide-induced macrophage gene expression by Rhodobacter sphaeroides lipid A and SDZ 880.431. Infect. Immun. 61:3518-3526.
13. Manthey, C. L., P. Y. Perera, C. A. Salkowski, and S. N. Vogel. 1994. Taxol provides a second signal for murine macrophage tumoricidal activity. J. Immunol. 152:825-831.
14. Manthey, C. L., N. Qureshi, P. L. Stutz, and S. N. Vogel. 1993. Lipopolysaccharide antagonists block taxol-induced signaling in murine macrophages. J. Exp. Med. 178:695-702.
15. Manthey, C. L., and S. N. Vogel. 1994. Taxol: a promising endotoxin research tool. J. Endotoxin Res. 1:189-198.
16. Monica, S., R. M. J. Palmer, and E. A. Higgs. 1991. Nitric oxide: physiology, pathophysiology, and parmacology. Pharmacol. Rev. 43:109-142.
17. Nathan, C., and Q.-W. Xie. 1994. Nitric oxide synthases: roles, tolls and controls. Cell 78:915-918.
18. Nogales, E., S. G. Wolf, l. A. Khan, R. F. Luduena, and K. H. Downing. 1995. Structure of tubulin at 6.5 A and location of the taxol-binding site. Nature (London) 375:424-427.
19. Obayashi, T., H. Tamura, S. Tanaka, M. Ohki, S. Takahashi, M. Arai, M. Masuda, and T. Kawai. 1985. A new chromogenic endotoxin-specific assay using rccombined limulus coagulation enzymes and its clinical applications. Clin. Chim. Acta 149:55-65.
20. Parness, J., and S. B. Horwit. 1981. Taxol binds to polymerized tubulin in vitro. J. Cell Biol. 91:479-487.
21. Pazdur, R., A. P. Kudelka, J. J. Kavanagh, P. R. Cohen, and M. N. Raber. 1993. The taxoids: paclitaxel (taxol) and docetaxel (taxotere). Cancer Treat. Rev. 19:351-386.
22. Ravindra, R., and R. S. Aronstam. 1991. Thyrotropin releasing hormone (TRH) receptor-G protein interactions in the rat anterior pituitary lobe are disrupted by colchicine and taxol. FASEB J. 5:A1498.
23. Ruff, M. R., and G. E. Gifford. 1980. Purification and physiochemical characterization of rabbit tumor necrosis factor. J. Immunol. 125:1671-1677.
24. Schiff, P. B., and S. B. Horwitz. 1980. Taxol stabilizes microtubules in mouse fibroblast cells. Proc. Natl. Acad. Sci. USA 77:1561-1565.
25. Schiff, P. B., J. Fant, and S. B. Horwit. 1979. Promotion of microtubule assembly in vitro by taxol. Nature (London) 277:665-667.
26. Schumann, R. R., S. R. Leong, G. W. Flaggs, P. W. Gray, S. D. Wright, J. C. Mathison, P. S. Tobias, and R. J. Ulevitch. 1990. Structure and function of lipopolysaccharide binding protein. Science 249:1429-1431.
27. Vale, R. D. 1987. Inracellular transport using microtubule-based motors. Annu. Rev. Cell Biol. 3:347-378.
28. Vodovotz, Y., D. Russell, Q.-W. Xie, C. Bogdan, and C. Nathan. 1995. Vesicle membrane association of nitric oxide synthase in primary mouse macrophages. J. Immunol. 154:2914-2925.
29. Wilson, L., J. R. Bamburg, S. B. Mizel, M. Grisham, and K. M. Creswell. 1974. Interaction of drugs with microtubule proteins. FASEB J. 33:158-166.
30. Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431-1433.