Differential effects of osteopontin on the cytotoxic activity of macrophages from young and old mice

Immunology

Volumn 88, Issue 4, 1996, Pages 642-647

  Rollo, E E ^a,b   Denhardt, D T ^a,c  

^a RUTGERS UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; LIPOPOLYSACCHARIDE; NITRIC OXIDE; OSTEOPONTIN; THIOGLYCOLIC ACID;

AGE; ANIMAL CELL; ARTICLE; CYTOTOXICITY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030016807     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.d01-691.x     Document Type: Article

References (30)

1. HOBBS M.V., WEIGLE W.O., NOONAN D.J. et al. (1993) Patterns of cytokine gene expression CD4+ by T cells from young and old mice. J Immunol 150, 3602.
2. FLURKEY K., STADECKER M. & MILLER R.A. (1992) Memory T lymphocyte hyporesponsiveness to non-cognate stimuli: a key factor in age related immunodeficiency. Eur J Immunol 22, 931.
3. HOBBS M.V., ERNST D.N., TORGETT B.E. et al. (1991) Cell proliferation and cytokine production by CD4+ cells from old mice. J Cell Biochem 46, 312.
4. WEKSLER M.E. (1993) Immune senescence and adrenal steroids: immune dysregulation and the action of dehydroepiandrosterone (DHEA) in old animals. Eur J Clin Pharmacol 45 (Suppl 1): S21; Discussion S43.
5. DING A., HWANG S. & SCHWAB R. (1994) Effect of aging on murine macrophages. Diminished response to IFN-γ for enhanced oxidative metabolism. J Immunol 153, 2146.
6. AMES B.N., SHIGENAGA M.K. & HAGEN T.M. (1993) Oxidants, antioxidants, and the degenerate diseases of aging. Proc Nail Acad Sci USA 90,7915.
7. SHIGENAGA M.K., HAGEN T.M. & AMES B.N. (1994) Oxidative damage and mitochondrial decay in aging. Proc Nail Acad Sci USA 91, 10771.
8. HWANG S.-M., WILSON P.D., LASKIN J.D. & DENHARDT DT. (1994) Age and development-related changes in osteopontin and nitric oxide synthase mRNA levels in human kidney proximal tubule epithelial cells: contrasting responses to hypoxia and reoxygenation. J Cell Physiol 160. 61.
9. GIACHELLI C.M., BAE N., LOMBARDI D., MAJESKY M. & SCHWARTZ S. (1991) Molecular cloning and characterization of 2B7, a rat mRNA which distinguishes smooth muscle cell phenotype in vitro and is identical to osteopontin (secreted phosphoprotein I, 2aR). Biochem Biophys Res Commun 177, 867.
10. LOPEZ C.A., HOYER J.R., WILSON P.D., WATERHOUSE P. & DENHARDT D.T. (1993) Heterogeneity of osteopontin expression among nephrons in mouse kidneys. Lab Invest 69, 355.
11. DENHARDT D.T. & Guo X. (1993) Osteopontin, a protein with diverse functions. FASEB J 7, 1475.
12. MIYAZAKI Y., SETOGUCHI M., YOSHIDA S., HIGUCHI Y., AKIZUKI S. & YAMAMOTO S. (1990) The mouse osteopontin gene. Expression in monocylic lineages and complete nucleotide sequence. J Biol Chem 265, 14432.
13. NEMIR M., DEVOLIGE M.W. & MUKHERJEE B.B. (1989) Normal rat kidney cells secrete both phosphorylated and nonphosphorylated forms of osteopontin showing different physiological properties. J Biol Chem 264. 18202.
14. PATARCA R., FREEMAN G.J., SINGH R.P. et al. (1989) Structural and functional studies of the early T-lymphocyte activation (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection. J Exp Med 170, 145.
15. SINGH R.P., PATARCA R., SCHWARTZ J., SINGH P. & CANTOR H. (1990) Definition of a specific interaction between the early T lymphocyte activation 1 (Eta-1) protein and murine macrophages in vitro and its effect upon macrophages in vivo. J Exp Med 171, 1931.
16. POLLACK S.B. LINNEMEYER P.A. & GILL S. (1994) Induction of osteopontin mRNA expression during activation of murine NK cells. J Leukoc Biol 55, 398.
17. SENGER D.R., PERRUZZI C.A., GRACEY C.F., PAPADOUPOULOS A. & TENEN D.G. (1988) Secreted phosphoproteins associated with neoplastic transformation: Close homology with plasma proteins cleaved during blood coagulation. Cancer Res 48. 5770.
18. SENGER D.R., PERRUZZI C.A. & PAPADOUPOULOS A. (1989) Elevated expression of secreted phosphoprotein 1 (osteopontin, 2ar) as a consequence of neoplastic transformation. Anticancer Res 9, 1291.
19. CRAIG A.M., BOWDEN G.T., CHAMBERS A.F. et al. (1990) Secreted phosphoprotein mRNA is induced during multistage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts. Int J Cancer 46, 133.
20. BEHREND E.I., CRAIG A.M., WILSON S.M., DENHARDT D.T. & CHAMBERS A.F. (1994) Reduced malignancy of ras-transformed NIH 3T3 cells expressing antisense osteopontin RNA. Cancer Res 54, 832.
21. HWANG S.-M., LOPEZ C.A., HECK D.E. et al. (1994) Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells. J Biol Chem 269, 711.
22. FENG B., ROLLO E.E. & DENHARDT D.T. (1995) Osteopontin (OPN) may facilitate metastasis by protecting cells from macrophage NO-mediated cytotxicity: evidence from cell lines down-regulated for OPN expression by a targeted ribozyme. Clin Exp Metastasis 13. 453.
23. CRAIG A.M., SMITH J.H. & Denhardt D.T. (1989) Osteopontin, a transformation-associated cell adhesion phosphoprotein. is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. J Biol Chem 264, 9682.
24. ADAMS D.O. (1979) Macrophages. In: Methods in Enzymology, Cell Culture (eds W.B. Jakoby & I.H. Pastan), Vol. 58, p. 494. Academic Press Inc.
25. LYONS C.R., ORLOFF G.J. & CUNNINGHAM J.M. (1992) Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage line. J Biol Chem 267. 6370.
26. IGNARRO L.J., FUKUTO J.M., GRISCAVAGE J.M., ROGERS N.E. & BYRNS R.E. (1993) Oxidation of NO in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed NO from L-arginine. Proc Natl Acad Sci USA 90, 8103.
27. LORSBACH R.B., MURPHY W.J., LOWENSTEIN C.J., SNYDER S.H. & RUSSELL S.W. (1993) Expression of the nitric oxide synthase gene in mouse macrophages activated for tumour cell killing. J Biol Chem 268, 1908.
28. DENHARDT D.T., LOPEZ C.A., ROLLO E.E., HWANG S.-M., AN X.-R. & WALTHER S.E. (1995) Osteopontin-induced modifications of cellular functions. In: Osteopontin, role in cell signalling and adhesion (eds D.T. Denhardt W.T. Butler A.F. Chambers & D.R. Senger), Vol. 760, p. 127. Annals NY Academy of Science.
29. WEBER G.F., ASHKAR S., GLIMCHER M.J. & CANTOR H. (1996) Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science 271, 509.
30. DENHARDT D.T. & CHAMBERS A.F. (1994) Overcoming obstacles of metastasis - defenses against those defenses: osteopontin (OPN) as a shield against attack by cytotoxic host cells. J Cell Biochem 56, 48.