Cloning of rabbit LCAT cDNA: Increase in LCAT mRNA abundance in the liver of cholesterol-fed rabbits

Journal of Lipid Research

Volumn 37, Issue 7, 1996, Pages 1616-1622

  Murata, Yukio ^a   Maeda, Eiichi ^a   Yoshino, Gen ^b   Kasuga, Masato ^a  

^a KOBE UNIVERSITY   (Japan)

^b TOHO UNIVERSITY   (Japan)

Author keywords

cholesterol; cholesterol feeding; LCAT; LCAT activity; LCAT cDNA; nucleotide sequence; reverse transport system

Indexed keywords

PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; CHOLESTEROL INTAKE; CHOLESTEROL TRANSPORT; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME REGULATION; GLYCOSYLATION; IMMUNOBLOTTING; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RABBIT; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; CHOLESTEROL, DIETARY; CLONING, MOLECULAR; DNA, COMPLEMENTARY; HUMANS; LIVER; MALE; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; RABBITS; RNA, MESSENGER;

EID: 0030016524     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Fielding, C. J., and P. E. Fielding. 1981. Evidence for a lipoprotein carrier in human plasma catalyzing sterol efflux from cultured fibroblasts and its relationship to lecithin:cholesterol acyltransferase. Proc. Natl. Acad. Sci. USA. 78: 3911-3914.
2. Fielding, C. J., and P. E. Fielding. 1982. Cholesterol transport between cells and body fluids: role of plasma lipoproteins and the plasma cholesterol esterification system. Med. Clin. North Am. 66: 363-373.
3. Rothblat, G. H., F. H. Mahlberg, W. J. Johnson, and M. C. Phillips. 1992. Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux. J. Lipid Res. 33: 1091-1097.
4. Vaisman, B. L., H-G. Klein, M. Rouis, A. M. Berald, M. R. Kindt, G. D. Tally, S. M. Meyn, R. F. Hoyt, Jr., S. M. Marcovina, J. J. Albers, J. M. Hoeg, H. B. Brewer, Jr., and S. Santamarina-Fojo. 1995. Overexpression of human lecithin:cholesterol acyltransferase leads to hyperalphalipoproteinemia in transgenic mice. J. Biol. Chem. 270: 12269-12275.
5. Mehlum, A., B. Staels, N. Duverger, A. Tailleux, G. Castro, C. Fievet, G. Luc, J-C. Fruchart, G. Olivecrona, G. Skretting, J. Auwerx, and H. Prydz. 1995. Tissue-specific expression of the human gene for lecithin:cholesterol acyltransferase in transgenic mice alters blood lipids, lipoproteins and lipases towards a less athrogenic profile. Eur. J. Biochem. 230: 567-575.
6. Francone, O. L., E. L. Gong, D. S. Ng, C. J. Fielding, and E. M. Rubin. 1995. Expression of human lecithin:cholesterol acyltransferase in transgenic mice. J. Clin. Invest. 96: 1440-1448.
7. Mclean, J., C. Fielding, D. Drayna, H. Dieplinger, B. Baer, W. Kohr, W. Henzel, and R. Lawn. 1986. Cloning and expression of human lecithin:cholesterol acyltransferase cDNA. Proc. Natl. Acad. Sci. USA. 83: 2335-2339.
8. Warden, C. H., C. A. Langer, J. I. Gorden, B. A. Taylor, J. W. Mclean, and A. J. Lusis. 1989. Tissue-specific expression, developmental regulation, and chromosomal mapping of the lecithin:cholesterol acyltransferase gene. J. Biol. Chem. 264: 21573-21581.
9. Meroni, G., N. Malgaretti, P. Magnaghi, and R. Taramelli. 1990. Nucleotide sequence of the cDNA for lecithin:cholesterol acyltransferase (LCAT) from the rat. Nucleic Acids Res. 18: 5308.
10. Hixon, J. E., D. M. Driscall, S. Birnbaum, and M. L. Britten. 1993. Baboon lecithin:cholesterol acyltransferase: cDNA sequences of two alleles, evolution, and gene expression. Gene. 128: 259-299.
11. Hengstschlager-Ottnad, E., K. Kuchler, and W. J. Schneider. 1995. Chicken lecithin:cholesterol acyltransferase; molecular characterization reveals unusual structure and expression pattern. J. Biol. Chem. 270: 26139-26145.
12. Hyunh, T. V., R. A. Young, and R. W. Davis. 1985. A practical approach. In DNA Cloning Techniques. D. M. Glover, editor. IRL Press, Oxford. Vol. I: 49-78.
13. Messing, J., R. Crea, and P. H. Seeburg. 1981. A system for shotgun DNA sequencing. Nucleic Acids Res. 9: 309-321.
14. Chirgwin, J. M., A. E. Przybyla, R. J. MacDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18: 5294-5299.
15. Scanu, A. M., C. T. Lim, and C. Edelstein. 1972. On the subunit structure of the protein of human serum high density lipoprotein. J. Biol. Chem. 247: 5850-5855.
16. Batzri, S., and E. D. Korn. 1973. Single bilayer liposomes prepared without sonication. Biochim. Biophys. Acta. 298: 1015-1019.
17. Yamazaki, S., T. Mitsunaga, Y. Fujiwara, and T. Nisida. 1983. Interaction of lecithin:cholesterol acyltransferase with human plasma lipoproteins and with lecithin-cholesterol vesicles. J. Biol. Chem. 258: 5847-5853.
18. Yang, C., D. Manoogian, Q. Pao, F-S. Lee, R. D. Knapp, A. M. Gotto, Jr., and H. J. Pownall. 1987. Lecithin:cholesterol acyltransferase. J. Biol. Chem. 262: 3086-3091.
19. Maeda, E., Y. Naka, T. Matozaki, M. Sakuma, Y. Akanuma, G. Yoshino, and M. Kasuga. 1991. Lecithin:cholesterol acyltransferase deficiency with a missense mutation in exon 6 of the LCAT gene. Biochem. Biophys. Res. Commun. 178: 460-466.
20. Chou, P. Y., and G. D. Fasman. 1978. Prediction of the secondary structure of proteins from their amino acid sequence. Adv. Enzymol. Relat. Areas Mol. Biol. 47: 45-148.
21. Kyte, J., and R. F. Doolittle. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157: 105-132.
22. Quintao, C. R. 1995. Is reverse cholesterol transport a misnomer for suggesting its role in the prevention of atheroma formation? Atherosclerosis. 116: 1-14.
23. von Eckardstein, A., Y. Huang, S. Wu, H. Funke, G. Noseda, and G. Assmann. 1995. Reverse cholesterol transport in plasma of patients with different forms of familial HDL deficiency. Arterioscler. Thromb. Vasc. Biol. 15: 691-703.
24. Weisweiler, P. 1987. Plasma lipoproteins and lipase and lecithin:cholesterol acyltransferase activities in obese subjects before and after weight reduction. J. Clin. Endocrinol. Metab. 65: 969-973.
25. Subbaiah, P. V., and R. A. Rodby. 1994. Abnormal acyltransferase activities and accelerated cholesteryl ester transfer in patients with nephrotic syndrome. Metabolism. 43: 1126-1133.
26. Bingle, C., S. Ghazi, J. S. Owen, and S. K. Srai. 1991. LCAT mRNA in liver disease. Lancet. 338: 1531.
27. Tsopanakis, C., D. Kotsarellis, I. Dontas, P. Karayannacos, and G. Skalkeas. 1988. Effects of cold stress on serum lipids, lipoproteins, and the activity of lecithin:cholesterol acyltransferase in rabbits. Biochem. Med. Metab. Biol. 39: 148-157.
28. Bielicki, J. K., M. R. McCall, J. J. M. van den Berg, F. A. Kuypers, and T. M. Forte. 1995. Copper and gas-phase cigarette smoke inhibit plasma lecithin:cholesterol acyltransferase activity by different mechanisms. J. Lipid Res. 36: 322-331.
29. Kodama, T., Y. Akanuma, M. Okazaki, H. Aburatani, H. Itakura, K. Takahashi, M. Sakuma, F. Takaku, and I. Hara. 1983. Abnormalities in plasma lipoprotein in familial partial lecithin:cholesterol acyltransferase deficiency. Biochim. Biophys. Acta. 752: 407-415.
30. Norum, K. R., and E. Gjone. 1967. Familial lecithin:cholesterol acyltransferase deficiency. Biochemical study of a newborn error of metabolism. Scand. J. Clin. Lab. Invest. 20: 231-243.
31. Francone, O. L., L. Evangelista, and C. J. Fielding. 1993. Lecithin:cholesterol acyltransferase: effects of mutagenesis at N-linked oligosaccharide attachment sites on acyl acceptor specificity. Biochim. Biophys. Acta. 1166: 301-304.
32. Qu, S-J., H-Z. Fan, F. Blanco Vaca, and H. J. Pownall. 1993. Effects of site-directed mutagenesis on the N-glycosylation sites of human lecithin:cholesterol acyltransferase. Biochemistry. 32: 8732-8736.
33. Mclean, J., K. Wion, D. Drayna, C. Fielding, and R. Lawn. 1986. Human lecithin:cholesterol acyltransferase gene: complete gene sequence and sites of expression. Nucleic Acids Res. 14: 9397-9406.
34. Warren, R. J., D. L. Ebert, P. J. Barter, and A. Mitchell. 1991. The regulation of hepatic lipase and cholesteryl ester transfer protein activity in the cholesterol-fed rabbit. Biochim. Biophys. Acta. 1086: 354-358.
35. Quinet, E. M., L. B. Agellon, P. A. Kroon, Y. L. Marcel, Y-C. Lee, M. E. Whitelock, and A. R. Tall. 1990. Atherogenic diet increases cholesteryl ester transfer protein messenger RNA levels in rabbit liver. J. Clin. Invest. 85: 357-363.